Difference between revisions of "IPLab:Lab 6:Acute Rejection"

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File:IPLab6AcuteRejection10.jpg|This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and cells within the renal tubules.  
 
File:IPLab6AcuteRejection10.jpg|This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and cells within the renal tubules.  
 
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== Virtual Microscopy ==
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<peir-vm>IPLab6AcuteRejection</peir-vm>
  
 
== Study Questions ==
 
== Study Questions ==

Revision as of 16:19, 3 January 2014

Clinical Summary[edit]

This 34-year-old white male with end-stage chronic glomerulonephritis had been receiving hemodialysis three times per week for 4 months when he was admitted to the hospital for a living related-donor transplantation from his mother. Other than the kidney disease, the patient was in good health. The transplant was performed successfully with no complications. However, eight days later, transplant rejection necessitated returning the patient to the operating room for a nephrectomy of the transplanted kidney. After the nephrectomy, the patient did quite well, was returned to hemodialysis, and was discharged home in good condition.

Autopsy Findings[edit]

The kidney weighed 240 grams and was edematous. The capsule stripped with ease to reveal a pale tan-brown cortex which was irregularly red-mottled. Upon sectioning, the cortical band was ill-defined, and the corticomedullary junction was not well-demarcated. The renal papillae were edematous and the renal pelvis displayed generalized petechial hemorrhages which extended through the 7-cm segment of ureter to a diffusely hemorrhagic terminal portion.

Images[edit]

Virtual Microscopy[edit]

Study Questions[edit]


Additional Resources[edit]

Reference[edit]

Journal Articles[edit]

Images[edit]

Related IPLab Cases[edit]

A normal kidney weighs 157 grams (range: 115 to 220 grams).

An infiltrate is an accumulation of cells in the lung parenchyma--this is a sign of pneumonia.

An infiltrate is an accumulation of cells in the lung parenchyma--this is a sign of pneumonia.