IPLab:Lab 6:Objectives

• Review in general terms the organization and effector cells of the immune system.
• Describe the Arthus reaction and serum sickness and relate them to hypersensitivity reactions.
• Define and describe the clinical, pathologic, and clinical laboratory features of rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis/polymyositis, Sjögren's syndrome, polyarteritis nodosa, and mixed connective tissue disease.
• Classify the histocompatibility antigens and how they relate to the major histocompatibility complex and to transplantation.
• Know prototypic organ rejection processes, giving the chronologic, immunologic, and morphologic features of each.
• Know the physical characteristics of amyloid which make it unique.
• Understand the different disease processes that can lead to amyloidosis and be able to characterize the different clinical sequelae of amyloidosis.