IPLab:Lab 12:Radiation Changes

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Clinical Summary

This 46-year-old white female was diagnosed with invasive squamous cell carcinoma of the cervix and subsequently received radiation therapy. Three years later the patient developed several episodes of small bowel obstruction which necessitated resection of a segment of ileum. She did well following surgery.

The surgical specimen consisted of a 13-cm segment of ileum having a luminal circumference of 5 cm. There was a full-thickness tear measuring 2.5 cm in the center of the specimen. On opening the bowel, the mucosa was ulcerated and showed a perforation.

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