IPLab:Lab 12:Radiation Changes

Images

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  This is a low-power photomicrograph of the surgical specimen of the ileum. The normal ileum is to the left (1). The area of stricture consists of dense fibrous connective tissue (2) and there is loss or marked atrophy of the epithelium (3).

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  This is a higher-power photomicrograph of the surgical specimen of the ileum showing the transition from the normal epithelium (1) to the atrophied epithelium (2) in the area of radiation injury.

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  This is a higher-power photomicrograph showing the atrophied epithelium in the area of radiation injury. There are some epithelial cells deep within the mucosa (1). Note the dense fibrous connective tissue (2) within the wall of the ileum.

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  This is a high-power photomicrograph showing the atrophied epithelium in the area of radiation injury (1). Note the dense fibrous connective tissue within the wall of the ileum and the congested blood vessels (2).

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  This is a high-power photomicrograph of the wall of the ileum showing a blood vessel that has suffered radiation-induced damage and is completely occluded (arrows).

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  This high-power photomicrograph of the wall of the ileum shows areas of fibrosis (1), inflammatory cells (2), and abnormal pleomorphic cells (3) in the area of radiation injury. The abnormal morphology of these cells is radiation-induced. These cells are often difficult to distinguish from recurrent tumor cells.

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  This high-power photomicrograph of the wall of the ileum shows more examples of pleomorphic cells (arrows) due to radiation injury.

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  This high-power photomicrograph of the wall of the ileum shows more examples of pleomorphic cells caused by radiation injury (arrows).