IPLab:Lab 1:Lung Abscess

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Contents

Clinical Summary

This 67-year-old male with advanced colon cancer developed obstruction of the bowel and underwent palliative surgeryPalliative surgery provides alleviation but is not curative. to remove an 8-cm portion of colon containing the obstruction. During the surgery the patient had several episodes of hypotension. After surgery he did not regain consciousness and required ventilator support. Four days after surgery, the patient developed a fever and his white blood cell count was found to be 15,256 cells/mm³A normal white blood cell count is 4000-11,000 cells/mm³.. Thus, he was started on broad-spectrum antibiotics. A chest x-ray demonstrated infiltratesAn infiltrate is an accumulation of cells in the lung parenchyma--this is a sign of pneumonia. in both lungs, which worsened over the next several days. His overall condition continued to deteriorate and he died 12 days after surgery.

Autopsy Findings

At autopsy, metastatic colon cancer was found throughout the abdominal cavity and invading into the liver. The lungs were markedly consolidatedConsolidation is the filling of lung air spaces with exudate--this is a sign of pneumonia. and had several focal abscessesAn abscess is a collection of pus (white blood cells) within a cavity formed by disintegrated tissue. that were 2 to 4 cm in diameter. Liquefied material poured out from inside these abscessesAn abscess is a collection of pus (white blood cells) within a cavity formed by disintegrated tissue. when the lungs were sliced.

Images

Virtual Microscopy

Lung Abscess

Normal Lung

Study Questions


Additional Resources

Reference

Journal Articles

Images

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