IPLab:Lab 1:Myocardial Infarction

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Clinical Summary

This was a 57-year-old male whose hospital course following abdominal surgery was characterized by progressive deterioration and hypotension. Four days post-operatively, the patient sustained an anterior myocardial infarctionMyocardial infarction is necrosis of myocardial tissue which occurs as a result of a deprivation of blood supply, and thus oxygen, to the heart tissue. Blockage of blood supply to the myocardium is caused by occlusion of a coronary artery. and died the next day.

Autopsy Findings

The patient's heart weighed 410 gramsA normal heart weighs 300 grams (range: 270 to 360 grams).. Examination of the coronary arteries revealed marked atherosclerotic narrowingAtherosclerosis is the deposition of lipid into the intima of arteries, resulting in narrowing of the vessel lumen. of all three vessels with focal occlusionAn occlusion is a blockage. by a thrombusA thrombus is a solid mass resulting from the aggregation of blood constituents within the vascular system. of the left anterior descending artery. Fresh necrosis of the anterior wall of the left ventricle and anterior portion of the septum was present, extending from the endocardium to the inner half of the ventricular wall.


Virtual Microscopy

Myocardial Infarction

Normal Heart

Study Questions

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