Changes

File:IPLab7Osteosarcoma7IPLab7Osteosarcoma7b.jpg|This is a photomicrograph of a decalcified histologic section from normal bone. Compare this normal morphology to the subsequent images of bone in this case of osteosarcoma.File:IPLab7Osteosarcoma8b.jpg|This is a higher-power photomicrograph of decalcified histologic section from this tumor. There are areas of osteoid (1) and cellular areas (2).File:IPLab7Osteosarcoma8IPLab7Osteosarcoma9b.jpg|This is a highhigher-power photomicrograph of decalcified histologic section showing the cellularity of the tumor. File:IPLab7Osteosarcoma9IPLab7Osteosarcoma10b.jpg|This highhigher-power photomicrograph demonstrates the cellular growth pattern. Note that the cells are fusiform pleomorphic and they grow in sheetsanaplastic. File:IPLab7Osteosarcoma10IPLab7Osteosarcoma11b.jpg|This high-power photomicrograph demonstrates the growth pattern and the cell morphology. File:IPLab7Osteosarcoma11.jpg|This is a high-power photomicrograph of the tumor cell morphology and the periosteum (arrow). File:IPLab7Osteosarcoma12.jpg|This high-power photomicrograph of the tumor demonstrates the fusiform morphology of the cells. Note the marked variability in size and staining intensity of the nuclei. File:IPLab7Osteosarcoma13.jpg|This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology. File:IPLab7Osteosarcoma14.jpg|This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology. File:IPLab7Osteosarcoma15IPLab7Osteosarcoma12b.jpg|This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology and multiple mitotic figures (arrows).