IPLab:Lab 3:Acute Appendicitis

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Clinical Summary[edit]

This 11-year-old male was admitted to the hospital with a complaint of 8 hours of severe pain in the right lower quadrant of the abdomen accompanied by nausea, vomiting, and diarrhea. Additional features on admission included a temperature of 101° F and a leukocytosis of 21,200 cells/mm³ with a shift to the left. An exploratory laparotomy revealed an inflamed appendix, retrocecal in location, which was adherent to the wall of the colon.

Autopsy Findings[edit]

The serosal surface of the appendix was covered with friable granular material. The lumen was dilated and contained a purulent exudate as well as a fecalith. The wall measured up to 0.4 cm in thickness.


Virtual Microscopy[edit]

Appendicitis (left) and Normal Appendix (right)[edit]

Study Questions[edit]

Additional Resources[edit]


Journal Articles[edit]


A normal white blood cell count is 4,000 to 11,000 cells per cubic mm.

A shift to the left indicates an increased ratio of immature PMNs (bands) to mature PMNs (segs).

Friable material is easily crumbled.

A fecalith is a hardened collection of fecal matter formed within the intestine.

An infiltrate is an accumulation of cells in the lung parenchyma--this is a sign of pneumonia.