Difference between revisions of "IPLab:Lab 9:Diphtheria"

From Pathology Education Instructional Resource
Jump to: navigation, search
(Images)
(Clinical Summary)
 
(6 intermediate revisions by 2 users not shown)
Line 2: Line 2:
 
This 4-year-old black female had an upper respiratory infection and a sore throat with increasing difficulty in breathing. Membranous exudate over one tonsil led to a working diagnosis of diphtheria, and the child was admitted. On the day of her admission, the child developed signs of respiratory tract obstruction and a tracheotomy was performed. However, the procedure was unable to establish a patent airway and the child died.
 
This 4-year-old black female had an upper respiratory infection and a sore throat with increasing difficulty in breathing. Membranous exudate over one tonsil led to a working diagnosis of diphtheria, and the child was admitted. On the day of her admission, the child developed signs of respiratory tract obstruction and a tracheotomy was performed. However, the procedure was unable to establish a patent airway and the child died.
  
== Autopsy Findings ==
+
At autopsy, a dense grayish pink membrane extended from both tonsils to the mid-trachea. The lungs were edematous and showed signs of pneumonia.
At autopsy, a dense grayish pink membrane extended from both tonsils to the mid-trachea. The lungs were edematous and showed signs of pneumonia.  
 
  
 
== Images ==
 
== Images ==
Line 12: Line 11:
 
File:IPLab9Diphtheria4.jpg|In this higher-power photomicrograph of the tissue from the previous image, the ulcerated tracheal mucosa and the diphtheritic membrane are more clearly seen. Although difficult to make out at this magnification, most of the cells in this inflammatory exudate are neutrophils.
 
File:IPLab9Diphtheria4.jpg|In this higher-power photomicrograph of the tissue from the previous image, the ulcerated tracheal mucosa and the diphtheritic membrane are more clearly seen. Although difficult to make out at this magnification, most of the cells in this inflammatory exudate are neutrophils.
 
</gallery>
 
</gallery>
 +
 +
== Virtual Microscopy ==
 +
<peir-vm>IPLab9Diphtheria</peir-vm>
  
 
== Study Questions ==
 
== Study Questions ==
Line 20: Line 22:
 
== Additional Resources ==
 
== Additional Resources ==
 
=== Reference ===
 
=== Reference ===
 
+
* [http://emedicine.medscape.com/article/782051-overview eMedicine Medical Library: Diphtheria]
 +
* [http://emedicine.medscape.com/article/963334-overview eMedicine Medical Library: Pediatric Pneumonia]
 +
* [http://emedicine.medscape.com/article/215100-overview eMedicine Medical Library: Corynebacterium Infections]
 +
* [http://www.merckmanuals.com/professional/infectious_diseases/gram-positive_bacilli/diphtheria.html Merck Manual: Diphtheria]
  
 
=== Journal Articles ===
 
=== Journal Articles ===
 
+
* Zakikhany K, Efstratiou A.  [http://www.ncbi.nlm.nih.gov/pubmed/22568715 Diphtheria in Europe: current problems and new challenges].  ''Future Microbiol'' 2012 May;7(5):595-607.
  
 
=== Images ===
 
=== Images ===
* [http://peir.path.uab.edu/library/index.php?/tags/2152-diphtheria PEIR Digital Library: Diphtheria Images]
+
* [{{SERVER}}/library/index.php?/tags/2152-diphtheria PEIR Digital Library: Diphtheria Images]
 
* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]
 
* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]
 
== Related IPLab Cases ==
 
 
  
 
{{IPLab 9}}
 
{{IPLab 9}}
  
 
[[Category: IPLab:Lab 9]]
 
[[Category: IPLab:Lab 9]]

Latest revision as of 21:43, 9 July 2020

Clinical Summary[edit]

This 4-year-old black female had an upper respiratory infection and a sore throat with increasing difficulty in breathing. Membranous exudate over one tonsil led to a working diagnosis of diphtheria, and the child was admitted. On the day of her admission, the child developed signs of respiratory tract obstruction and a tracheotomy was performed. However, the procedure was unable to establish a patent airway and the child died.

At autopsy, a dense grayish pink membrane extended from both tonsils to the mid-trachea. The lungs were edematous and showed signs of pneumonia.

Images[edit]

Virtual Microscopy[edit]

Study Questions[edit]


Additional Resources[edit]

Reference[edit]

Journal Articles[edit]

Images[edit]

In alcoholics, aspiration pneumonia is common--bacteria enter the lung via aspiration of gastric contents.