IPLab:Lab 1:Lung Abscess

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Clinical Summary[edit]

This 67-year-old male with advanced colon cancer developed obstruction of the bowel and underwent palliative surgery to remove an 8-cm portion of colon containing the obstruction. During the surgery the patient had several episodes of hypotension. After surgery he did not regain consciousness and required ventilator support. Four days after surgery, the patient developed a fever and his white blood cell count was found to be 15,256 cells/mm³. Thus, he was started on broad-spectrum antibiotics. A chest x-ray demonstrated infiltrates in both lungs, which worsened over the next several days. His overall condition continued to deteriorate and he died 12 days after surgery.

Autopsy Findings[edit]

At autopsy, metastatic colon cancer was found throughout the abdominal cavity and invading into the liver. The lungs were markedly consolidated and had several focal abscesses that were 2 to 4 cm in diameter. Liquefied material poured out from inside these abscesses when the lungs were sliced.

Images[edit]

Virtual Microscopy[edit]

Lung Abscess[edit]

Normal Lung[edit]

Study Questions[edit]


Additional Resources[edit]

Reference[edit]

Journal Articles[edit]

Images[edit]

Related IPLab Cases[edit]

Palliative surgery provides alleviation but is not curative.

A normal white blood cell count is 4000-11,000 cells/mm³.

An infiltrate is an accumulation of cells in the lung parenchyma--this is a sign of pneumonia.

Consolidation is the filling of lung air spaces with exudate--this is a sign of pneumonia.

An abscess is a collection of pus (white blood cells) within a cavity formed by disintegrated tissue.

An abscess is a collection of pus (white blood cells) within a cavity formed by disintegrated tissue.

In alcoholics, aspiration pneumonia is common--bacteria enter the lung via aspiration of gastric contents.