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IPLab:Lab 3:Lobar Pneumonia

127 bytes added, 23:01, 19 June 2020
Autopsy Findings
On admission, the pertinent findings included a temperature of 104°, a white cell count of 22,700 cells/mm³, nuchal rigidity, elevated spinal fluid pressure, and the presence of Gram-positive diplococci on a smear of spinal fluid (cultures of blood and spinal fluid were subsequently reported positive for Streptococcus pneumoniae). The patient expired 12 hours after admission in spite of intensive antibiotic therapy.
== Autopsy Findings ==The At autopsy the right lung weighed 800 grams. The most striking finding was a marked uniform consolidation of the entire middle lobe which was reddish-gray in color. There was also marked thickening of the pleura overlying the middle lobe.
== Images ==
File:IPLab3LobarPneumonia8.jpg|This is a photomicrograph of alveoli filled with exudate. The alveolar wall outlines (arrows) are barely visible in this section. The alveoli are filled with PMNs, fibrin, and edema fluid. This is a severe acute inflammatory response but the structure of the alveoli remains intact. This tissue is able, with proper treatment, to completely resolve this inflammatory response. Since there has not been necrosis of the lung tissue itself (loss of tissue), this lung could completely recover normal function (resolution).
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== Virtual Microscopy ==
=== Lung: Lobar Pneumonia ===
<peir-vm>IPLab3LobarPneumonia</peir-vm>
 
=== Normal Lung ===
<peir-vm>UAB-Histology-00107</peir-vm>
== Study Questions ==
=== Images ===
* [http://peir.path.uab.edu{{SERVER}}/library/index.php?/tags/573-lobar_pneumonia PEIR Digital Library: Lobar Pneumonia Images]
* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#1 WebPath: Pneumonias]
=== Related IPLab Cases ===
* [[IPLab:Lab 3:Bronchopneumonia|Lab 3: Lung: Bronchopneumonia]]
* [[IPLab:Lab 4:Septic Emboli|Lab 4: Lung and Heart: Septic Emboli]]