This 70-year-old man was admitted to the hospital with a three week history of upper abdominal pain, anorexia, nausea, and general malaise, all of approximately three weeks' duration. His hospital stay was characterized by fever and severe respiratory distress. There were multiple densities in the patient's chest x-ray consistent with pneumonia and examination of a stained sputum specimen showed acid fast bacilli. Despite intensive appropriate therapy, the patient progressively deteriorated and died 14 days after admission.

== Autopsy Findings ==It was determined at autopsy that the patient suffered from findings demonstrated pulmonary tuberculosis with widespread dissemination throughout the body. The left lung weighed 620 grams and the right lung 1230 grams. These were characterized by marked pulmonary congestion and pulmonary edema. In addition, multiple Multiple gray-white nodules ranging from pinpoint size up to 1 cm were diffusely distributed throughout the lung parenchyma.

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File:IPLab1Tuberculosis4IPLab1Tuberculosis4b.jpg|This is a low-power photomicrograph of a histology section from the lung of this patient with a chronic history of respiratory disease. Note the multiple eosinophilic nodules (arrows) seen at low power in this section. Other areas of the lung are relatively normal and several bronchi and large vessels can be seen at this low power. The pleural surface of the lung is at the left right and the remaining edges are cut edges of the tissue block.File:IPLab1Tuberculosis5IPLab1Tuberculosis5b.jpg|This higher-power photomicrograph of the eosinophilic nodules (arrows) illustrates their discreet nature and the surrounding inflammatory response in the remaining normal lung tissue.File:IPLab1Tuberculosis6IPLab1Tuberculosis6b.jpg|This photomicrograph shows a single nodule with an amorphous eosinophilic center and accumulations of cells around the outer edge. This is typical of a granuloma associated with tuberculosis in which there is a necrotic center (1*) and a rim of lymphocytes, macrophages, and occasional a multinucleated giant cells cell (arrow) around the periphery.File:IPLab1Tuberculosis7IPLab1Tuberculosis7b.jpg|This is a higher-power view of the a granuloma with the amorphous eosinophilic material representing caseation necrosis (1*), a giant cells near the center cell (2arrow), and inflammatory cells around the periphery.File:IPLab1Tuberculosis8.jpg|This is a high-power photomicrograph of the Langhans-type multinucleated giant cell which is characteristic of tuberculous granulomas (arrow). Note the horseshoe shape of the nuclei in this giant cell. The majority of the cells in the upper left portion of this section are macrophages which provide the major cellular component in a granuloma. Note the smaller number of small blue-staining cells in the peripheral portions of this granuloma to the left of which are lymphocytes.

* [http://peir.path.uab.edu{{SERVER}}/library/index.php?/tags/259-tuberculosis PEIR Digital Library: Tuberculosis Images]