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Created page with "== Clinical Summary == The patient is a 74 year old female with a history of sarcoma of the right thigh and a new lung mass. === Past Medical History === * Sarcoma of thigh..."
== Clinical Summary ==
The patient is a 74 year old female with a history of sarcoma of the right thigh and a new lung mass.
=== Past Medical History ===
* Sarcoma of thigh (3 years prior)
* Osteoarthritis
=== Past Surgical History ===
* Previous excision of thigh sarcoma.
* Hysterectomy
==Radiology==
* CT showed a right upper lobe low density nodule measuring 3.0 x 2.6 cm which is abutting the pleural surface.
===Clinical Plan===
The patient was scheduled for an endobronchial ultrasound guided fine needle aspiration biopsy.
==Pathology==
===Cytology===
<gallery heights="250px" widths="250px">
CytologicallyYoursCoW20140227Cytology1.jpg|20x magnification showing adipose tissue, atypical cells and bubbly appearing nuclei.
CytologicallyYoursCoW20140227Cytology2.jpg|20x magnification showing adipose tissue
CytologicallyYoursCoW20140227Cytology3.jpg|60x magnification showing bizarre appearing malignant cells with unusual bubbly nuclei and adjacent adipose tissue.
CytologicallyYoursCoW20140227Cytology4.jpg|40x magnification showing bizarre appearing malignant cells with unusual bubbly nuclei and adjacent adipose tissue.
CytologicallyYoursCoW20140227Cytology5.jpg|40x magnification showing bizarre appearing malignant cells with unusual bubbly nuclei and adjacent adipose tissue.
</gallery>
<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer">Click here to toggle the diagnosis and discussion.</div>
<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
<div class="mw-collapsible-content">
==Final Diagnosis==
===Cytology===
* '''Positive for malignancy, favor liposarcoma'''.
===Biopsy===
<gallery heights="250px" widths="250px">
CytologicallyYoursCoW20140206Biopsy1.jpg|20x magnification of pleomorphic nuclei and lipoblasts.
CytologicallyYoursCoW20140206Biopsy1.jpg|40x magnification of pleomorphic nuclei and lipoblasts.
</gallery>
===Previous Soft Tissue Biopsy Diagnosis===
* '''High grade pleomorphic liposarcoma'''.
===Discussion===
The diagnosis of pleomorphic liposarcoma on cytology rests on the presence of highly atypical, sometimes multinucleated lipoblasts. The scalloped nucleus is an important diagnostic feature.
</div></div>
{{Cytologically Yours}}
[[Category:Case Reports]]
The patient is a 74 year old female with a history of sarcoma of the right thigh and a new lung mass.
=== Past Medical History ===
* Sarcoma of thigh (3 years prior)
* Osteoarthritis
=== Past Surgical History ===
* Previous excision of thigh sarcoma.
* Hysterectomy
==Radiology==
* CT showed a right upper lobe low density nodule measuring 3.0 x 2.6 cm which is abutting the pleural surface.
===Clinical Plan===
The patient was scheduled for an endobronchial ultrasound guided fine needle aspiration biopsy.
==Pathology==
===Cytology===
<gallery heights="250px" widths="250px">
CytologicallyYoursCoW20140227Cytology1.jpg|20x magnification showing adipose tissue, atypical cells and bubbly appearing nuclei.
CytologicallyYoursCoW20140227Cytology2.jpg|20x magnification showing adipose tissue
CytologicallyYoursCoW20140227Cytology3.jpg|60x magnification showing bizarre appearing malignant cells with unusual bubbly nuclei and adjacent adipose tissue.
CytologicallyYoursCoW20140227Cytology4.jpg|40x magnification showing bizarre appearing malignant cells with unusual bubbly nuclei and adjacent adipose tissue.
CytologicallyYoursCoW20140227Cytology5.jpg|40x magnification showing bizarre appearing malignant cells with unusual bubbly nuclei and adjacent adipose tissue.
</gallery>
<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer">Click here to toggle the diagnosis and discussion.</div>
<div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
<div class="mw-collapsible-content">
==Final Diagnosis==
===Cytology===
* '''Positive for malignancy, favor liposarcoma'''.
===Biopsy===
<gallery heights="250px" widths="250px">
CytologicallyYoursCoW20140206Biopsy1.jpg|20x magnification of pleomorphic nuclei and lipoblasts.
CytologicallyYoursCoW20140206Biopsy1.jpg|40x magnification of pleomorphic nuclei and lipoblasts.
</gallery>
===Previous Soft Tissue Biopsy Diagnosis===
* '''High grade pleomorphic liposarcoma'''.
===Discussion===
The diagnosis of pleomorphic liposarcoma on cytology rests on the presence of highly atypical, sometimes multinucleated lipoblasts. The scalloped nucleus is an important diagnostic feature.
</div></div>
{{Cytologically Yours}}
[[Category:Case Reports]]
