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CytologicallyYoursCoW20131216Cytology3.jpg|40x magnification of pleural fluid (ThinPrep). Chromatin is irregular and clumped with salt and pepper appearance; although, occasional nucleoli are also seen.
CytologicallyYoursCoW20131216Cytology4.jpg|40x magnification of pleural fluid (ThinPrep). Some nuclear molding can be appreciated and a mitotic figure is present.
CytologicallyYoursCoW20131216Cytology5.jpg|Cell block of pleural fluid. Group of malignant cells showing nuclear molding, scant cytoplasm, and salt and pepper chromatin. Nucleoli are also seen.
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====Other immunostainsperformed====* BerEp4*Moc31* Calretinin* TTF1* Chromogranin* Synaptophysin* CD56* Napsin A
====Resident Questions====
==Final Diagnosis==
===Cytology===
* Rapid diagnosis: Non-small Small cell carcinoma.* Final diagnosis: Renal cell carcinoma.
==Case Discussion==
This is a classic case of metastatic renal small cell carcinomain pleural fluid.
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