This 55-year-old white male had a long history of emphysema and a 60-70 pack-year smoking history. He was in his usual state of health until about one month before admission, at which time he developed increasing dyspnea on exertion. At the same time, his sputum increased from two tablespoons to half a cup of yellow blood-streaked sputum a day. Chest x-ray showed a right hilar mass. Sputum cytology revealed abnormal cells that were "positive for malignancy." He later developed pneumonia and fever. The patient expired soon thereafter.
== Images ==
File:IPLab7Bronchogenic3.jpg|This is a photomicrograph of bronchus with ulcerated mucosal surface on the right (1). The submucosa is completely filled with tumor down to the cartilage (2).
File:IPLab7Bronchogenic4.jpg|This is a higher-power photomicrograph of bronchus with the ulcerated mucosal surface on the right and tumor underneath.
IPLab7Bronchogenic5.jpg|This is a higher -power photomicrograph of the mucosal surface (right) with an area of hemorrhage (arrow) and underlying tumor (left). File:IPLab7Bronchogenic6.jpg|This is a photomicrograph of tumor from an area of invasion with compression of fibrous stroma and focal necrosis. File:IPLab7Bronchogenic7.jpg|This is a high-power photomicrograph showing cytologic detail of the tumor with an area of necrosis (1) and a more differentiated area with keratin pearl formation ( 2). File: IPLab7Bronchogenic8.jpg|This is a high power photomicrograph of tumor with an area of central necrosis (arrow). File: IPLab7Bronchogenic9.jpg|This high-power photomicrograph of tumor shows the cytologic detail of a less-differentiated area of neoplasm with cellular anaplasia.
== Study Questions ==
=== Images ===
http://peir.path.uab.edu/library/index.php?/tags/27-lung/112-carcinoma PEIR Digital Library: Lung Carcinoma Images]
* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html WebPath: Pulmonary Pathology]