Cytologically Yours: Unknowns: 201311: Case 4

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Clinical History[edit]

57 year old female with hypoechoic nodule on ultrasound.


Resident Questions[edit]

Cytologic Features[edit]

  • Variable cytology/histology
  • Polygonal, spindled, plasmacytoid
  • Intranuclear pseudoinclusions
  • Usually uniform, but can have some pleomorphism
  • There may be red cytoplasmic granules on DiffQuik and the chromatin is often salt and pepper

The normal fibrinogen level is 184 to 412 mg/dL.