Difference between revisions of "IPLab:Lab 8:Poliomyelitis"

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== Clinical Summary ==
 
== Clinical Summary ==
  
Six days before his death, this 31-year-old white male became acutely ill with fever followed by an ascending paralysis which began in his feet. Three days later he was hospitalized because of difficulty in breathing. A lumbar puncture was performed and the patient's spinal fluid contained increased protein and polymorphonuclear leukocytes (4.30 PMNs/cmm). He died on the third hospital day.  
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Six days before his death, this 31-year-old white male became acutely ill with fever followed by an ascending paralysis which began in his feet. Three days later he was hospitalized because of difficulty in breathing. A lumbar puncture was performed and the patient's spinal fluid contained increased protein and polymorphonuclear leukocytes (4.30 PMNs/mm³). He died on the third hospital day.
  
 
== Autopsy Findings ==  
 
== Autopsy Findings ==  
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File:IPLab8Polio5.jpg|This is another high-power photomicrograph of the anterior horn with inflammatory cell infiltrate and total loss of neurons.  
 
File:IPLab8Polio5.jpg|This is another high-power photomicrograph of the anterior horn with inflammatory cell infiltrate and total loss of neurons.  
 
</gallery>
 
</gallery>
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== Virtual Microscopy ==
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=== Poliomyelitis ===
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<peir-vm>IPLab8Polio</peir-vm>
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=== Normal Spinal Cord ===
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<peir-vm>IPLab8Polio-Normal_cord</peir-vm>
  
 
== Study Questions ==
 
== Study Questions ==
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=== Images ===
 
=== Images ===
 
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* [{{SERVER}}/library/index.php?/tags/2149-polio PEIR Digital Library: Polio Images]
 
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* [http://library.med.utah.edu/WebPath/CNSHTML/CNSIDX.html#7 WebPath: CNS Pathology: Acquired and Congenital Degenerative Diseases]
== Related IPLab Cases ==
 
 
 
  
 
{{IPLab 8}}
 
{{IPLab 8}}
  
 
[[Category: IPLab:Lab 8]]
 
[[Category: IPLab:Lab 8]]

Latest revision as of 16:30, 3 January 2014

Clinical Summary[edit]

Six days before his death, this 31-year-old white male became acutely ill with fever followed by an ascending paralysis which began in his feet. Three days later he was hospitalized because of difficulty in breathing. A lumbar puncture was performed and the patient's spinal fluid contained increased protein and polymorphonuclear leukocytes (4.30 PMNs/mm³). He died on the third hospital day.

Autopsy Findings[edit]

At autopsy, the thoracic and lumbar portions of the spinal cord were softer than normal and focally hemorrhagic.

Images[edit]

Virtual Microscopy[edit]

Poliomyelitis[edit]

Normal Spinal Cord[edit]

Study Questions[edit]


Additional Resources[edit]

Reference[edit]

Journal Articles[edit]

Images[edit]

Normally, there should be no PMNs in a patient's spinal fluid.

An infiltrate is an accumulation of cells in the lung parenchyma--this is a sign of pneumonia.