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→Clinical Summary
This 63-year-old white male had recurrent thickening and scaling of the lower lip for two years. In recent months, it had undergone ulceration and progressive enlargement. The lesion was excised by a wedge resection.
== Images ==
File:IPLab7LipSCC8.jpg|This is a section of muscle tissue from this biopsy of the lip. Note that the squamous cell carcinoma has infiltrated into the muscle tissue. There are also inflammatory cells within this area of tumor infiltration.
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== Virtual Microscopy ==
<peir-vm>IPLab7LipSCC</peir-vm>
== Study Questions ==
=== Journal Articles ===
* Guenthner ST, Hurwitz RM, Buckel LJ, Gray HR. [http://www.ncbi.nlm.nih.gov/pubmed/10459120 Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation]. ''J Am Acad Dermatol'' 1999 Sep;41(3 Pt 1):443-8.
* Ling S, Hu Z, Yang Z, Yang F, Li Y, Lin P, Chen K, Dong L, Cao L, Tao Y, Hao L, Chen Q, Gong Q, Wu D, Li W, Zhao W, Tian X, Hao C,Hungate EA, Catenacci DV, Hudson RR, Li WH, Lu X, Wu CI. [http://www.pnas.org/content/112/47/E6496.full.pdf Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution.]. ''Proc Natl Acad Sci U S A'' 2015 Nov 24;112(47):E6496-505.
=== Images ===
* [http://peir.path.uab.edu{{SERVER}}/library/index.php?/tags/254-squamous_cell_carcinoma PEIR Digital Library: Squamous Cell Carcinoma Images]
* [http://library.med.utah.edu/WebPath/NEOHTML/NEOPLIDX.html WebPath: Neoplasia]
== Related IPLab Cases ==
* [[IPLab:Lab 7:Esophagus SCC|Lab 7: Esophagus: Squamous Cell Carcinoma]]* [[IPLab:Lab 7:IDC|Lab 7: Breast: Infiltrating Ductal Carcinoma]]* [[IPLab:Lab 7:Bronchogenic Carcinoma|Lab 7: Lung: Bronchogenic Carcinoma]]* [[IPLab:Lab 7:Adenocarcinoma|Lab 7: Colon: Adenocarcinoma]]* [[IPLab:Lab 7:Metastatic Adenocarcinoma|Lab 7: Lung & Liver: Metastatic Adenocarcinoma]]
{{IPLab 7}}
[[Category: IPLab:Lab 7]]
