Difference between revisions of "Cytologically Yours: CoW: 20140213"

From Pathology Education Instructional Resource
Jump to: navigation, search
(Created page with "== Clinical Summary == The patient is a 66yo old male presenting with jaundice. === Past Medical History === * History of prostate cancer 5 years ago. * Hyperlipidemia * Chr...")
 
Line 31: Line 31:
  
 
====Resident Questions====
 
====Resident Questions====
* <spoiler text="The radiologic differential diagnosis was between osteosarcoma and Ewing sarcma. What would be a possible diagnostic pitfall?"> The confusion between osteosarcoma and Ewing may occur with the small cell variant of osteosarcoma.   </spoiler>
+
* <spoiler text="What is your initial diagnosis?"> This was initially called adenocarcinoma on rapid diagnosis during the endoscopic ultrasound guided procedure. </spoiler>
  
 +
===Cell Block===
 +
<gallery heights="250px" widths="250px">
 +
CytologicallyYoursCoW20140213Biopsy1.jpg|40x magnification of cell block of pancreatic mass showing small glands with macronucleoli.
 +
 +
* <spoiler text="What special stains do you order?">  </spoiler>
  
 
<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer">Click here to toggle the diagnosis and discussion.</div>
 
<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer">Click here to toggle the diagnosis and discussion.</div>
Line 40: Line 45:
 
==Final Diagnosis==
 
==Final Diagnosis==
 
===Cytology===
 
===Cytology===
* '''High grade sarcoma, favor osteosarcoma'''.
+
* '''Metastatic prostate carcinoma'''.
 +
 
  
  
===Biopsy===
 
<gallery heights="250px" widths="250px">
 
CytologicallyYoursCoW20140206Biopsy1.jpg|20x magnification of bone biopsy showing sclerotic bone.
 
  
 
</gallery>
 
</gallery>

Revision as of 22:11, 4 March 2014

Clinical Summary

The patient is a 66yo old male presenting with jaundice.

Past Medical History

  • History of prostate cancer 5 years ago.
  • Hyperlipidemia
  • Chronic back pain

Past Surgical History

  • Prostatectomy (2009)
  • Thyroidectomy (2004)

Ultrasound

  • Ultrasound of head of pancreas shows a 43mm x 23mm ill defined mass.

Clinical Plan

The differential diagnosis included pancreatic adenocarcinoma and metastatic prostate cancer.

Pathology

Cytology


Resident Questions


Cell Block

Biopsy Diagnosis

  • Conventional high grade sarcoma, sclerotic type.


Discussion

The experience of FNA of osteosarcoma is mainly with conventional high-grade intramedullary sarcoma and to the rare high-grade surface osteosarcoma. Smears usually contain dissociated neoplastic cells and cell clusters.