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Cytologically Yours: CoW: 20140213

51 bytes added, 22:22, 4 March 2014
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====Resident Questions====
* <spoiler text="The radiologic differential What was the initial diagnosis was between osteosarcoma and Ewing sarcma. What would be a possible diagnostic pitfallon rapid interpretation?"> The confusion between osteosarcoma and Ewing may occur with the small cell variant of osteosarcomaAdenocarcinoma. </spoiler>
====Cell Block====
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CytologicallyYoursCoW20140213Biopsy1.jpg|40x magnification of cell block of pancreatic mass showing small glands with macronucleoli.
 
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* <spoiler text="What stains do you order?"> We ordered PSA, CK7, and CA19.9. </spoiler>
<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer">Click here to toggle the diagnosis and discussion.</div>
==Final Diagnosis==
===Cytology===
* '''High grade sarcoma, favor osteosarcomaMetastatic prostate carcinoma'''. 
===Biopsy===
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CytologicallyYoursCoW20140206Biopsy1CytologicallyYoursCoW20140213Biopsy2.jpg|20x magnification of bone biopsy showing sclerotic bone.PSA shows positive staining
</gallery>
===Biopsy Diagnosis===* CK7 Negative* '''Conventional high grade sarcoma, sclerotic type'''CA19.9 Negative* PSA Positive
===Discussion===
The experience of FNA of osteosarcoma is mainly with conventional high-grade intramedullary sarcoma and Metastatic prostate carcinoma to the pancreas is rare high-grade surface osteosarcoma; however, long term survival of prostate cancer may increase the incidence. Smears usually contain dissociated neoplastic cells and Renal cell clusterscarcinoma is the most metastatic pancreatic tumor.
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Retrieved from "https://peir.path.uab.edu/wiki/Special:MobileDiff/2770...2783"

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