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04:12, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto9.jpg (This higher-power photomicrograph of a cryptococcal organism shows more clearly the nucleus surrounded by the large extracellular capsule (arrows).)
04:12, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto8.jpg (Cryptococcal organisms can also be seen in this high-power photomicrograph of the cryptococcal lesion. Some of the organisms have a well-defined halo (arrows) due to the mucopolysaccharide coat which surrounds them.)
04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto7.jpg (This is another high-power photomicrograph of the cryptococcal lesion. In this section, numerous cryptococcal organisms (5-10 mm in diameter) can be seen (arrows). Note that there is very little inflammatory reaction.)
04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto6.jpg (This is a high-power photomicrograph of the cryptococcal lesion. Some of the organisms have been expelled during processing, but some cryptococcal organisms can be seen (arrows).)
04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto5.jpg (This is a higher-power photomicrograph of the cryptococcal lesion. The air spaces are filled with organisms (arrows).)
04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto4.jpg (This is a low-power photomicrograph of the lung from the lesion seen on x-ray. Note that there is little, if any, inflammatory reaction.)
04:10, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto3.jpg (This is another section of this lung showing consolidation (arrows).)
04:10, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto2.jpg (This is a gross photomicrograph of this lung taken at autopsy. Note the areas of emphysema (1) and consolidation (2).)
04:10, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto1.jpg (This is the chest x-ray showing the mass (arrow) in the right lower lobe.)
04:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo7.jpg (This photomicrograph was taken under oil immersion to show the silver-stained Histoplasma organisms. Some of the organisms appear to be budding (arrows).)
04:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo6.jpg (This is a high-power photomicrograph of the same section of tissue as the previous slide. This section, however, has been stained with methenamine silver which causes the Histoplasma organisms to stain black (arrows).)
04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo5.jpg (This high-power photomicrograph shows small (2-5 mm) dark-staining organisms in the cytoplasm of many of these cells (arrows).)
04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo4.jpg (This high-power photomicrograph was taken at the edge of the area of necrosis. There is a mild inflammatory infiltrate along the edge of the necrosis.)
04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo3.jpg (This is an even higher-power photomicrograph of an area of necrosis (arrows). There is loss of cellular detail within this area. There are inflammatory cells present; however, it is difficult to differentiate the inflammatory cells from the native lymp...)
04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo2.jpg (This higher-power photomicrograph of the previous adrenal gland shows more clearly the irregularly-shaped area of necrosis (arrows).)
04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo1.jpg (This low-power photomicrograph shows a section of adrenal gland with several irregularly-outlined areas of necrosis.)
04:04, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis8.jpg (This is a higher-power photomicrograph of a Candida colony in the kidney. Note the pseudohyphae of the Candida organisms.)
04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis7.jpg (This is a low-power photomicrograph of the kidney from this same case. Note the Candida colonies (arrows). The pseudohyphae are evident around the periphery of these colonies even at this low magnification.)
04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis6.jpg (This high-power photomicrograph shows the yeasts (1) and pseudohyphae (2).)
04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis5.jpg (This higher-power photomicrograph shows the yeasts and pseudohyphae in this focus of Candida organisms.)
04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis4.jpg (This is a low-power photomicrograph of one of the Candida colonies from this lymph node. The chains of yeast which are termed "pseudohyphae" are apparent at this magnification.)
04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis3.jpg (This is a low-power photomicrograph of lymph node with three prominent areas of Candida colonies (arrows). Even at this low magnification, the purple-staining yeast and pseudohyphae can be easily seen. This section was stained with Periodic Acid-Schiff...)
04:02, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis2.jpg (This photograph of the cut surface of these kidneys shows that these multifocal punctate lesions are primarily in the cortex (arrows).)
04:02, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis1.jpg (This autopsy photograph of the kidneys demonstrates the multifocal punctate lesions visible on the serosal surface (arrows). Don't confuse these small yellow punctate lesions with the fat that is adherent to the renal capsule.)
03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis5.jpg (This is a high-power photomicrograph of an actinomycotic colony. The filamentous nature (arrows) of the actinomyces organisms is more easily appreciated at this power.)
03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis4.jpg (This is an even higher-power photomicrograph of actinomycotic colonies in the abscess. The filamentous nature (arrows) of the actinomyces organisms in these colonies can be appreciated.)
03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis3.jpg (This is a higher-power photomicrograph of actinomycotic colonies in the abscess.)
03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis2.jpg (This is a higher-power photomicrograph of an abscess demonstrating a pocket of purulent exudate that contains numerous actinomycotic colonies (arrows).)
03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis1.jpg (This is a low-power photomicrograph of the retroperitoneal abscess. At this magnification, multiple dark-staining foci can be appreciated. These foci are Actinomyces colonies (arrows). These colonies are known as "sulfur granules" because in gross spec...)
03:57, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium7.jpg (This is a high-power photomicrograph of a tissue section stained with a tissue Gram's stain (Brown & Brenn). The Gram-positive bacilli can be seen throughout this tissue section.)
03:57, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium6.jpg (This higher-power photomicrograph of the previous image provides a clearer view of gas bubbles in the tissue, the necrotic hypereosinophilic muscle cell (1), and the mild inflammatory reaction (2). At this magnification, the bacteria located throughout...)
03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium5.jpg (This high-power photomicrograph shows the gas accumulation present in the tissue, a necrotic muscle cell (1), and a mild inflammatory response (2). There is also a thrombosed blood vessel (3). The blue-staining rods (bacterial organisms) can barely be ...)
03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium4.jpg (This is a high-power photomicrograph of skeletal muscle. The muscle cells are hypereosinophilic and most do not contain nuclei, indicating that these cells are dead or dying. The round clear spaces (1) in this tissue correspond to gas accumulations pri...)
03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium3.jpg (This is a low-power photomicrograph of muscle fascicles containing large gas bubbles (arrows). Note that there is no inflammatory reaction in this section.)
03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium2.jpg (This gross photograph shows a close-up view of hemorrhagic blebs (arrows) on the skin. The blebs on the skin are accumulations of gas being discharged into the tissues from the Clostridium perfringens. This gas produces crepitance.)
03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium1.jpg (This gross photograph of the lower extremity was taken at autopsy. Notice the swelling and the area of the primary infection (arrow).)
03:53, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF6.jpg (This high-power photomicrograph of myocardium shows the cellular detail of another Aschoff body. In this case there appears to be a multinucleated Aschoff giant cell (arrow).)
03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF5.jpg (This high-power photomicrograph of myocardium shows the cellular detail of an Aschoff body. Aschoff bodies are foci of fibrinoid necrosis surrounded by lymphocytes, macrophages, an occasional plasma cell, and plump “activated” histiocytes called An...)
03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF4.jpg (This is a higher-power photomicrograph of myocardium containing Aschoff bodies (arrows) within the interstitium.)
03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF3.jpg (This is a higher-power photomicrograph of myocardium showing cellular accumulations--Aschoff bodies (arrows)--within the interstitium of the myocardium. These are found especially around blood vessels.)
03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF2.jpg (This is a low-power photomicrograph of heart tissue. Little can be seen at this magnification, except that the tissue looks relatively normal.)
03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF1.jpg (This is a gross photograph of mitral valve demonstrating marked thickening and fibrosis of the valve leaflet. There are also numerous foci of fibrinoid necrosis within the cusps and friable vegetations (verrucae) along the lines of closure (arrows). Th...)
03:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria4.jpg (In this higher-power photomicrograph of the tissue from the previous image, the ulcerated tracheal mucosa and the diphtheritic membrane are more clearly seen. Although difficult to make out at this magnification, most of the cells in this inflammatory ...)
03:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria3.jpg (This is an even higher-power photomicrograph of the tracheal mucosa and the diphtheritic membrane. The mucosal surface of the trachea is ulcerated (total loss of epithelial cells) and the only remaining epithelial cells are found in the glands (arrows)...)
03:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria2.jpg (This is a higher-power photomicrograph of trachea with the diphtheritic membrane (1). Even though, the main part of the membrane has pulled away from the tracheal lining during histological processing, in this section part of the membrane is still loos...)
03:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria1.jpg (This is a low-power photomicrograph of the trachea with the diphtheritic membrane (1), which has pulled away from the tracheal lining during histological processing. Note the tracheal cartilage (2) present in this section.)
03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis8.jpg (This photomicrograph of brain tissue demonstrates diffuse edema.)
03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis7.jpg (This is a high-power photomicrograph of exudate from the leptomeninges which has been Gram-stained. Note the Gram-negative bacteria (arrows) throughout this section.)
03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis6.jpg (This is a high-power photomicrograph of a blood vessel from the previous image. The vessel is surrounded by neutrophils (arrows).)
03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis5.jpg (This is a higher-power photomicrograph of inflammatory exudate in a sulcus. The majority of cells in this exudate are neutrophils. There is also abundant fibrin (arrows) and red blood cells are present in the congested vessels.)
03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis4.jpg (This higher-power photomicrograph of a sulcus shows the congested vessels and the inflammatory exudate in the leptomeninges.)
03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis3.jpg (This is a higher-power view of a congested blood vessel. Inflammatory exudate is present within the vessel and throughout the leptomeninges.)
03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis2.jpg (This is a low-power photomicrograph of brain section. Note the exudate (1) in the meninges and congestion of the vessels (2) in the leptomeninges.)
03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis1.jpg (This gross photograph of the autopsy specimen from this case demonstrates the purulent exudate (arrows) in the leptomeninges.)
03:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF8.jpg (This is a high-power photomicrograph of a thrombosed vessel in the dermis. Note that the endothelial cells are missing along part of the circumference of the vessel (arrows)--this is where the main part of the thrombus has attached. Also note the infla...)
03:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF7.jpg (This is a high-power photomicrograph of a dermal vessel (arrow) which is exhibiting vasculitis and thrombosis.)
03:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF6.jpg (This is a high-power photomicrograph of severe vasculitis in the dermis.)
03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF5.jpg (This is a photomicrograph of dermis with an area of more severe vasculitis (arrow).)
03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF4.jpg (This is a higher-power photomicrograph of a dermal vessel with mild vasculitis.)
03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF3.jpg (This is a photomicrograph of a small vessel in the dermis which is demonstrating mild vasculitis.)
03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF2.jpg (This is a higher-power photomicrograph demonstrating areas of hemorrhage immediately underneath the epidermis. Also note the cellularity and thrombosis of the small vessels in the dermis (arrow).)
03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF1.jpg (This is a low-power photomicrograph of the skin biopsy. Note areas of hemorrhage (arrow) in the dermis.)
02:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV10.jpg (This high-power photomicrograph of the previous section shows the HBcAg positive nuclei (arrows).)
02:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV9.jpg (This is a low-power photomicrograph of the same liver reacted with antibody specific for hepatitis B core antigen (HBcAg). The hepatocytes that contain HBcAg stain brown. Note that even at this low magnification, many brown-staining nuclei can be seen.)
02:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV8.jpg (This higher-power photomicrograph of the previous section shows more clearly the HBsAg positive cells (arrows). Upon staining with H&E, these same cells exhibit a "ground glass" appearance, which is due to the accumulation of HBsAg in the hepatocyte cy...)
02:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV7.jpg (This is a low-power photomicrograph of liver from the previous image which has been reacted with antibody specific for HBsAg. The hepatocytes that contain HBsAg stain brown.)
02:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV6.jpg (This is a photomicrograph of a liver section from another case of hepatitis B. In this H&E-stained section, the typical "ground glass" appearance of the hepatocytes can be appreciated (arrows).)
02:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV5.jpg (This high-power photomicrograph showing hepatocytes, the cytoplasm of which contain intracytoplasmic accumulations (arrows) of hepatitis B surface antigen.)
02:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV4.jpg (This is a high-power photomicrograph of liver with numerous hepatocytes containing accumulations of magenta-staining material in the cytoplasm (arrows).)
02:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV3.jpg (This is a higher-power photomicrograph of the periportal region exhibiting some inflammation and bile duct hyperplasia. There is also congestion and some loss of hepatocytes with disruption of the hepatic cords.)
02:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV2.jpg (This is a higher-power photomicrograph of liver from this case. Note the severe congestion (RBCs in sinusoids) and the presence of occasional hepatocytes with dark red/magenta-stained cytoplasm (arrows).)
02:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV1.jpg (This is a low-power photomicrograph of liver from this case. This section was stained with a modified aldehyde fuchsin and counterstained with hematoxylin and eosin. Modified aldehyde fuchsin colors cystine-rich proteins--such as HBsAg and elastic fibe...)
02:44, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio5.jpg (This is another high-power photomicrograph of the anterior horn with inflammatory cell infiltrate and total loss of neurons.)
02:44, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio4.jpg (This is a higher-power photomicrograph taken at the junction of the white and gray matter. Note the inflammatory cellular infiltrate and tissue breakdown. There is significant loss of neurons and myelin in this area.)
02:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio3.jpg (This is a high-power photomicrograph of the anterior horn of the spinal cord from this case. Note the absence of motor neurons and the diffuse gliosis.)
02:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio2.jpg (This is a higher-power photomicrograph of spinal cord from this case. Note the absence of motor neurons in the anterior horns and the gliosis (arrows).)
02:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio1.jpg (This is a low-power photomicrograph of a section of spinal cord from this case. Note that the anterior horns (arrows) are almost completely devoid of neurons.)
02:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies5.jpg (This is a high-power photomicrograph of a neuron surrounded by inflammatory cells (lymphocytes and microglia). This neuron has two intracytoplasmic eosinophilic inclusion bodies (arrows).)
02:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies4.jpg (This is a high-power photomicrograph of neurons containing variably-sized intracytoplasmic eosinophilic inclusion bodies (arrows).)
02:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies3.jpg (This is a higher-power photomicrograph of the shrunken neurons. One neuron appears to have an eosinophilic intracytoplasmic inclusion body (arrow).)
02:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies2.jpg (This is a medium-power photomicrograph of brain tissue exhibiting edema and evidence of shrunken, necrotic neurons (arrows).)
02:39, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies1.jpg (This is a low-power photomicrograph of the hippocampus (arrow) from this case.)
02:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis12.jpg (This is a photomicrograph of a brain section stained with an antibody against herpes simplex. Even at this magnification, it is easy to pick out cells that are positive for the virus (arrows).)
02:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis11.jpg (This is another high-power photomicrograph of a cell containing an intranuclear inclusion body (arrow).)
02:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis10.jpg (This is another high-power photomicrograph of a cell containing an intranuclear inclusion body (arrow). Note that the nuclear chromatin has been pushed to the outer edges of the nucleus.)
02:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis9.jpg (This is a high-power photomicrograph demonstrating cells containing intranuclear inclusion bodies (arrows).)
02:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis8.jpg (This is a high-power photomicrograph showing several necrotic cells (arrows).)
02:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis7.jpg (This is a high-power photomicrograph demonstrating clear areas, which indicate edema, and numerous shrunken red necrotic cells (1). At this power, it can be seen that eosinophilic intranuclear inclusion bodies have displaced chromatin to the periphery ...)
02:35, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis6.jpg (This is another high-power photomicrograph showing a blood vessel with perivascular hemorrhage and mild perivascular lymphocytic cuffing (arrow). In addition, there are numerous red shrunken neurons and glia with pyknotic nuclei throughout this section.)
02:35, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis5.jpg (This is a high-power photomicrograph of the previous section. At this power it is easier to see the blood vessel with the perivascular hemorrhage and mild perivascular lymphocytic cuffing (1). In addition, the areas of edema and loss of neurophil (2) c...)
02:35, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis4.jpg (This is a medium-power photomicrograph showing a blood vessel with perivascular hemorrhage (1), areas with loss of brain parenchyma, and edema (2). Even at this power, it can be seen that many of the cells are shrunken and dark red, suggesting that the...)
02:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis3.jpg (This is a low-power photomicrograph showing a section of brain with numerous perivascular hemorrhages (arrows) and some areas that appear hypercellular.)
02:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis2.jpg (This is a closer view of the previous section of brain showing multiple small, punctate hemorrhages throughout the brain parenchyma (arrows).)
02:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis1.jpg (This is a gross photograph of a section of brain showing multiple small, punctate hemorrhages throughout the brain parenchyma (arrows).)
02:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis5.jpg (This is a high-power photomicrograph of epithelium near the edge of the ulcer. The cells that have been invaded by the herpes virus contain intranuclear accumulations of amphophilic viral inclusions (arrows).)
02:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis4.jpg (This is a higher-power photomicrograph of epithelium at the edge of the ulcer. Amphophilic intranuclear inclusion bodies can be seen in almost all of the epithelial cells in this section.)
02:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis3.jpg (This is a medium-power photomicrograph of epithelium at the edge of the ulcer. Even at this power, amphophilic (dark, blue-purple-staining) intranuclear inclusion bodies can be seen in the epithelial cells. Note the inflammatory infiltrate in the subep...)
02:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis2.jpg (This higher-power photomicrograph shows the epithelium (1), the edge of the ulcer (2), and the ulcerated epithelium (3). There is an inflammatory exudate at the base of the ulcer and some necrotic cells where the epithelium once was present.)
02:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis1.jpg (This is a low-power photomicrograph showing a cross section of the tongue. There is an area along the surface of the tongue where the normal epithelium has been lost and there are areas of ulceration (arrows).)
02:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma15.jpg (This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology and multiple mitotic figures (arrows).)
02:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma14.jpg (This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology.)
02:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma13.jpg (This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology.)
02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma12.jpg (This high-power photomicrograph of the tumor demonstrates the fusiform morphology of the cells. Note the marked variability in size and staining intensity of the nuclei.)
02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma11.jpg (This is a high-power photomicrograph of the tumor cell morphology and the periosteum (arrow).)
02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma10.jpg (This high-power photomicrograph demonstrates the growth pattern and the cell morphology.)
02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma9.jpg (This high-power photomicrograph demonstrates the cellular growth pattern. Note that the cells are fusiform and they grow in sheets.)
02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma8.jpg (This is a high-power photomicrograph of decalcified histologic section showing the cellularity of the tumor.)
02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma7.jpg (This is a higher-power photomicrograph of decalcified histologic section from this tumor. There are areas of osteoid (1) and cellular areas (2).)
02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma6.jpg (This is a low-power photomicrograph of decalcified histologic section from this tumor. Note the blue color (cell nuclei stain blue) of much of this section indicating the increased cellularity of the tumor.)
02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma5.jpg (These are cut sections of the distal femur containing the tumor. The periosteal involvement is evident from this picture (arrows).)
02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma4.jpg (This is a gross photograph of the surgical specimen with tissue dissected away to demonstrate the tumor mass.)
02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma3.jpg (This is another view of the tumor in the distal femur.)
02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma2.jpg (This is a radiograph showing the tumor in the distal femur.)
02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma1.jpg (This is a photograph of the patient prior to surgery. Note the marked swelling of the knee.)
02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid11.jpg (This is a high-power view of the same section stained with a silver stain to delineate carcinoid tumor cells (brown).)
02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid10.jpg (This is a higher-power view of the previous section stained with a silver stain to delineate carcinoid tumor cells (brown) and a mucin stain (blue) to stain the glands.)
02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid9.jpg (This is a low-power photomicrograph of a section of cecum containing tumor stained to demonstrate the secretory granules in these tumor cells (brown-colored stain). The blue color is the mucin in the glands just under the mucosal surface.)
02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid8.jpg (This is a higher-power photomicrograph of the previous section showing intact mucosa (1), a gland (2), and the submucosal carcinoid tumor cells (3).)
02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid7.jpg (This is a low-power photomicrograph of another one of the subcutaneous masses in the cecum. The mucosa is normal and the tumor cells are in the submucosa.)
02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid6.jpg (This is a higher-power photomicrograph of the previous section showing the intact mucosa (right) and the submucosal carcinoid tumor.)
02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid5.jpg (This is a low-power photomicrograph of one of the subcutaneous masses in the cecum. Note that the mucosa (1) is virtually normal and the tumor cells are in the submucosa (2).)
02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid4.jpg (This is a high-power photomicrograph of the surgical specimen showing the cellular morphology. The tumor cells are monotonously similar with scant, pink, granular cytoplasm and a round-to-oval stippled nucleus. As in most carcinoid tumors, there is min...)
02:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid3.jpg (This is a high-power photomicrograph of the surgical specimen showing the tumor's growth pattern--cells form discrete islands, trabeculae, and glands.)
02:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid2.jpg (This is a higher-power photomicrograph of the surgical specimen showing nests of tumor cells (arrows).)
02:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid1.jpg (This is a low-power photomicrograph of the surgical specimen showing basophilic and eosinophilic areas delimiting areas of tumor infiltration.)
02:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic9.jpg (This high-power photomicrograph of tumor shows the cytologic detail of a less-differentiated area of neoplasm with cellular anaplasia.)
02:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic8.jpg (This is a high power photomicrograph of tumor with an area of central necrosis (arrow).)
02:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic7.jpg (This is a high-power photomicrograph showing cytologic detail of the tumor with an area of necrosis (1) and a more differentiated area with keratin pearl formation (2).)
02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic6.jpg (This is a photomicrograph of tumor from an area of invasion with compression of fibrous stroma and focal necrosis.)
02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic5.jpg (This is a higher-power photomicrograph of the mucosal surface (right) with an area of hemorrhage (arrow) and underlying tumor (left).)
02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic4.jpg (This is a higher-power photomicrograph of bronchus with the ulcerated mucosal surface on the right and tumor underneath.)
02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic3.jpg (This is a photomicrograph of bronchus with ulcerated mucosal surface on the right (1). The submucosa is completely filled with tumor down to the cartilage (2).)
02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic2.jpg (This is a low-power photomicrograph of bronchus showing normal mucosa (1) with transition to carcinoma (2). Note the bronchial cartilage (3) and the invasion of tumor through the entire wall of the bronchus with tumor extending to the serosal surface (4).)
01:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic1.jpg (This is a gross photograph of bronchogenic carcinoma. The large tumor mass can be seen adjacent to the bronchus (1). Note that the epithelial surface of the bronchus is rough and irregular (2). The first branch off the right main stem bronchus is parti...)
01:57, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma8.jpg (This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eo...)
01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma7.jpg (This is a high-power photomicrograph of the main tumor mass with the cells growing as poorly formed nests and sheets of cells. There is little if any pigment in this section.)
01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma6.jpg (This is a higher magnification showing the abundant extracellular melanin surrounding the tumor cells (brown pigment).)
01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma5.jpg (This is a higher-magnification showing the abundant extracellular melanin (arrows) surrounding the tumor cells. This section of neoplasm shows the numerous cells with abundant cytoplasm and brown pigment within the cytoplasm of some of these cells.)
01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma4.jpg (This higher-power photomicrograph shows the remaining portion of lymph node (arrow). The rest of the lymph node is invaded by a neoplasm composed of cells with lighter eosinophilic cytoplasm and pigment.)
01:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma3.jpg (This is a low-power photomicrograph of lymph node that is almost completely replaced/filled with tumor. This lymph node has a capsule (1) and some remaining lymphocytes (2) but the remainder of the node is replaced by tumor cells.)
01:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma2.jpg (This is a gross photograph of lymph nodes almost entirely replaced by black pigment (melanin).)
01:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma1.jpg (This is a gross photograph of skin with melanoma. Note the black pigment, multiple satellite nodules, and focal ulceration. Some of the satellite nodules affect the nipple.)
01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC8.jpg (This is a high-power photomicrograph demonstrating the growth pattern of the tumor. The tumor consists of malignant duct-lining cells growing in cords, solid cell nests, tubules, and glands. The cytologic detail of tumor cells varies from small cells w...)
01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC7.jpg (This is a section taken at the periphery of the tumor showing bands of tumor cells infiltrating into the fat tissue.)
01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC6.jpg (This is a section of breast tumor with abundant fibrous tissue throughout the tumor (desmoplasia, scirrhous carcinoma).)
01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC5.jpg (This is a high-power photomicrograph showing the cellular and nuclear features of the tumor cells. The large epithelial cells form glands and are medium-sized with a moderate amount of cytoplasm, vesicular nuclei, and nucleoli.)
01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC4.jpg (This is a higher-magnification showing abundant groups of tumor cells dissecting through the breast parenchyma - tumor infiltration (infiltrating duct cell carcinoma).)
01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC3.jpg (This is a section of breast with small groups of carcinoma cells throughout the breast tissue and invading through the dermis.)
01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC2.jpg (These are sections of normal breast (lower) and breast tissue with infiltrating duct carcinoma (upper). Note the increased cellularity (increased blue staining due to the increased number of nuclei) in the tumor tissue.)
01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC1.jpg (This is a gross photograph of the surgical specimen of breast with infiltrating duct carcinoma. Note the tumor tissue under the area of the nipple. The tumor infiltrates in an irregular fashion into the breast parenchyma. Note the nipple retraction cau...)
01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic9.jpg (This is a high-power photomicrograph of the edge of the tumor nodule in the lung. The tumor cells area growing in a glandular pattern. The area of necrosis is evident at the right side of the image.)
01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic8.jpg (This is a high-power photomicrograph of the edge of the tumor nodule in the lung. The tumor cells are infiltrating into the lung parenchyma (1). Even at this power you can see the glandular formation of this adenocarcinoma. There is a large area of nec...)
01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic7.jpg (This is a photomicrograph of a tumor nodule in the lung. The tumor cells are infiltrating into the lung parenchyma (1). There is a large area of necrosis in the center of the tumor (2).)
01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic6.jpg (This is a high-power photomicrograph of tumor cells that are forming glands (arrows).)
01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic5.jpg (This is a higher-power photomicrograph showing how the tumor cells (arrows) have infiltrated into the liver parenchyma.)
01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic4.jpg (This is a photomicrograph taken at the interface between the tumor (top) and the normal liver parenchyma (bottom).)
01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic3.jpg (These are low-power photomicrographs of a section of liver (left) and lung (right) containing tumor nodules (arrows).)
01:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic2.jpg (This gross photograph of the lung from this case also demonstrates multiple, variably sized pale/white-tan nodules scattered throughout the lung.)
01:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic1.jpg (This gross photograph of the liver from this case demonstrates multiple, variably-sized pale/white-tan nodules scattered throughout the liver.)
01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA9.jpg (This is a segment of distal colon from another case. Note the annular tumor that severely compromises the lumen of the colon. There is dilation of the colon proximal to the tumor.)
01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA8.jpg (This gross photograph from another case demonstrates an ulcerated adenocarcinoma (arrows) at the rectosigmoid junction.)
01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA7.jpg (This is a high-power photomicrograph of tumor cells forming glands.)
01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA6.jpg (This is a high-power photomicrograph of tumor cells forming glands.)
01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA5.jpg (This is a high-power photomicrograph of tumor cells invading the underlying muscularis.)
01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA4.jpg (This is a higher-power photomicrograph of the area of transition between the normal (1) and the neoplastic (2) epithelium.)
01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA3.jpg (This photomicrograph of the surgical specimen shows the transition between normal mucosa on the left and carcinoma which is invading the wall of the bowel (arrow).)
01:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA2.jpg (This is a closer view of the previous image demonstrating the raised, annular carcinoma (arrows).)
01:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA1.jpg (This is a gross photograph of the adenoma from the surgical specimen in this case. Note the large, ulcerated, fungating annular (encircling) carcinoma (1) with areas of hemorrhage (2). Also note the adenomatous polyps (3).)
01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC7.jpg (This is a high-power photomicrograph of the tumor cells that have invaded the adjacent muscle tissue.)
01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC6.jpg (This is a higher-power photomicrograph of bands of tumor cells (arrows) extending between the muscle bundles.)
01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC5.jpg (This is a photomicrograph of bands of tumor cells invading into the adjacent tissues (arrows).)
01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC4.jpg (This is a higher-power photomicrograph showing invasive squamous cell carcinoma. Tongues and islands of tumor cells exhibit areas of central necrosis (arrow).)
01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC3.jpg (This is a high-power photomicrograph demonstrating the normal epithelium undergoing transition to carcinoma (arrows).)
01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC2.jpg (This low-power photomicrograph of a cross-section through the esophagus at the area of constriction shows extensive infiltration of the esophageal wall with squamous cell carcinoma (arrows).)
01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC1.jpg (This is a gross photograph of the luminal surface of the esophagus with the area of constriction (1). The area protrudes into the lumen. There is also a central area of ulceration (2).)
01:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC8.jpg (This is a section of muscle tissue from this biopsy of the lip. Note that the squamous cell carcinoma has infiltrated into the muscle tissue. There are also inflammatory cells within this area of tumor infiltration.)
01:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC7.jpg (This is a high power photomicrograph of a poorly-differentiated area of tumor. Note the spindle-shaped cells and the irregular pattern of growth.)
01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC6.jpg (This is a high power photomicrograph of the well-differentiated squamous cell carcinoma. Note the intracytoplasmic keratinization which gives the cells a glassy appearance. The focal accumulations of keratinized cells are called keratin pearls (arrows).)
01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC5.jpg (This is a higher-power photomicrograph of infiltrating squamous cell carcinoma and inflammatory cells.)
01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC4.jpg (This is a higher-power photomicrograph of the well-differentiated squamous cell carcinoma and the inflammatory cell infiltration.)
01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC3.jpg (This photomicrograph shows a large area of ulceration (arrow) with underlying congestion and hemorrhage. The area of ulceration is adjacent to an area of tumor infiltration.)
01:31, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC2.jpg (This is a low-power photomicrograph of squamous cell carcinoma of the lip. Note focal ulceration (1) and tumor infiltration at the vermilion border (2).)
01:31, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC1.jpg (This is a pre-op photograph of this patient with an ulcerated lesion on his lip (arrow). Also note that the lip is somewhat thickened. The area for surgical excision is delineated by black marker.)
01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma7.jpg (This is a higher magnification of fibroadenoma showing irregularly shaped ducts lined by two layers of cells as previously described.)
01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma6.jpg (This is a high magnification of the fibroadenoma showing the dense stroma of the tumor surrounding the irregularly shaped duct. The ducts are lined by two cell layers, one of cuboidal, two columnar cells (inner layer) and an outer layer of flattened ce...)
01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma5.jpg (This is a higher-power photomicrograph of fibroadenoma showing ducts embedded in connective tissue.)
01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma4.jpg (This photomicrograph shows the compressed connective tissue (arrow) between two nodules of dense fibrous tissue and ducts.)
01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma3.jpg (This is a higher magnification of the fibroadenoma showing the dense stroma of the tumor surrounding the irregularly shaped ducts. The adjacent fibrofatty tissue containing breast ducts and lobules has been compressed by the tumor.)
01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma2.jpg (This is a higher magnification of one of the three nodules. At this power, the nodule seems to be composed of a solid parenchyma with small glandular spaces. The adjacent breast parenchyma consists mostly of fat.)
01:26, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma1.jpg (This low-power photomicrograph of the surgical specimen demonstrates three ovoid, well-circumscribed nodules surrounded by fibroadipose tissue.)
01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma6.jpg (This high-power photomicrograph demonstrates the relatively normal cellular morphology of this follicular adenoma.)
01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma5.jpg (This is a photomicrograph of an adenoma. Note that the follicular architecture is well developed and more or less uniform throughout this section.)
01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma4.jpg (This photomicrograph demonstrates the densely packed follicular pattern in the adenoma (left) and the larger colloid-filled follicles of the normal thyroid (right). An area of compressed thyroid is present adjacent to the adenoma (arrows).)
01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma3.jpg (This is another higher-power photomicrograph of the adenoma (left) and the adjacent thyroid tissue (right). Note the compression of the adjacent normal thyroid and the difference in morphology between the adenoma and the thyroid.)
01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma2.jpg (This is a higher-power view of the border between the tumor mass and the adjacent thyroid tissue. Note that the mass has compressed the adjacent normal thyroid tissue (arrow). Also note the different morphology between the adenoma (very cellular, dense...)
01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma1.jpg (This is a low-power photomicrograph of a nodule found in the thyroid of this case. Note that the mass is well-circumscribed and there is a sharp line of demarcation between the mass and the adjacent thyroid tissue (arrows).)
21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection10.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and cells within the renal tubules.)
21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection9.jpg (This is a high-power photomicrograph of cells infiltrating the wall of the blood vessel.)
21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection8.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium (1) and in the wall of the blood vessel (2).)
21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection7.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and in the wall of the blood vessel on the left.)
21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection6.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrate within the interstitium. There is some degeneration (coagulative necrosis) of tubules and glomeruli.)
21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection5.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrate within the interstitium and around the small blood vessel in the center of the image.)
21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection4.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrates within this kidney section. Note that in addition to the diffuse cellularity, the focal accumulations of cells appear to be focused around blood vessels.)
21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection3.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrates within this kidney section.)
21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection2.jpg (This is a low-power photomicrograph of the kidney that was removed from this patient. Even at this low power you can appreciate the focal accumulations of cells within this section and the diffuse cellular infiltrate (blue dots) throughout the kidney p...)
21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection1.jpg (This is a gross photograph of a kidney with acute rejection from an autopsy case. Note that the kidney is swollen (edema and inflammation) and there are areas of hemorrhage throughout the kidney.)
21:51, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection12.jpg (Photomicrograph from another region of previous image. Note the cellular infiltrate around a small blood vessel (right) and neutrophils within renal tubules (arrow).)
21:51, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection11.jpg (This is a higher-power photomicrograph of kidney from the previous image demonstrating the cellular infiltrate which is comprised of lymphocytes, macrophages, plasma cells and a few neutrophils.)
21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection10.jpg (This is a high-power photomicrograph of a kidney from another case of chronic transplant rejection. In this case there is extensive damage to the kidney due to the chronic rejection (loss of tubules and glomerular lesions). In addition, this kidney was...)
21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection9.jpg (This is a high-power photomicrograph of a damaged glomerulus. Note the loss of normal capillary structure, the mesangial expansion and the infiltration of large mononuclear cells.)
21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection8.jpg (This is a high-power photomicrograph of renal cortex with cellular infiltrate and few remaining renal tubules. The cellular infiltrate comprises macrophages, activated (large) lymphocytes and a few neutrophils and plasma cells.)
21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection7.jpg (This is a photomicrograph of a glomerulus with a mild cellular infiltrate (left) and a small damaged glomerulus (right). There is extensive interstitial fibrosis (1), loss of renal tubules, and the remaining tubules contain protein (2) indicating sever...)
21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection6.jpg (This is a photomicrograph of rejected kidney with a focus of cellular infiltrate (left) and a small artery with neointimal proliferation and stenosis (arrow).)
21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection5.jpg (This high-power photomicrograph of glomeruli from this kidney demonstrates congestion (1), increased cellularity of glomeruli with mesangial expansion, and a glomerulus that is almost completely obliterated or sclerosed (2).)
21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection4.jpg (This is another area of renal cortex similar to the previous image. Note the fibrosis (1) and loss of renal tubules throughout this section. Also note the focus of inflammatory cells (2) indicating that despite the chromic nature of this lesion, there ...)
21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection3.jpg (This is a photomicrograph of kidney with a focal area of hemorrhage around a small blood vessel (left) and congestion of the glomeruli. Note that there is a marked loss of renal tubules throughout this section with replacement by fibrous connective tis...)
21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection2.jpg (This is a higher-power photomicrograph of kidney containing a section of blood vessel that demonstrates a marked neointimal proliferative response (1). In this case the lumen of the artery is obliterated. Also note the cellular infiltrate in the inters...)
21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection1.jpg (This is a low-power photomicrograph of the kidney from this case of chronic transplant rejection. Note the focal areas of hemorrhage and inflammatory cell infiltrate in this section.)
21:43, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM4.jpg (This is a photograph of the vertebral column from this patient at autopsy. Notice the collapsed vertebra (1). There are multiple variably-sized white nodules (2) within the bone marrow. These are accumulations of malignant plasma cells in this case of ...)
21:43, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM3.jpg (This high-power photomicrograph demonstrates the cells that make up this tissue. These cells resemble plasma cells and are the malignant cell of multiple myeloma.)
21:42, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM2.jpg (This higher-power photomicrograph shows the junction between an amorphous hyaline-appearing area (amyloid) on the right and cellular areas (plasmacytoid cells) on the left.)
21:42, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM1.jpg (This is a low-power photomicrograph of the mediastinal mass. The mass is encapsulated and contains cellular areas (blue) and areas of pale red material.)
21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid11.jpg (This photomicrograph of the tongue demonstrates extensive amyloid deposits (1) separating the skeletal muscle fibers of the tongue. In many cases the amyloid encircles the muscle fibers (2) and these muscle fibers are atrophied.)
21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid10.jpg (This photomicrograph of kidney demonstrates the amyloid deposits (arrows) within glomeruli.)
21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid9.jpg (This is a gross photograph of kidney from this case. Note the pale yellow material within the cortex (arrows). This is indicative of amyloid within the cortex and the glomeruli. Also note that there are multiple red spots in the cortex. These represent...)
21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid8.jpg (This is a photomicrograph of Congo-red-stained liver tissue viewed with partially polarized light. Although not well demonstrated in this image, Congo-red-stained amyloid viewed through polarized light should give off a classic “apple green” birefr...)
21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid7.jpg (This is a high-power view of liver tissue stained with Congo red. The orange amyloid material (arrows) is seen clearly between liver parenchymal cells.)
21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid6.jpg (This is a low-power photomicrograph of liver tissue stained with Congo red (orange color in slide). Congo red reacts with amyloid and gives it an orange color (arrows).)
21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid5.jpg (This is a higher-power photomicrograph showing the amyloid deposits (1) between hepatocytes (2).)
21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid4.jpg (This is a low-power photomicrograph of liver tissue from this case. Note the eosinophilic hyaline material (1) present within and between the hepatic tissue (2). There is marked distortion of lobular architecture by the amyloid.)
21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid3.jpg (This is a closer view of the cut surface of this liver. The pale waxy material can be seen within the hepatic tissue (arrows).)
21:33, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid2.jpg (This is a gross picture of the cut surface of the liver from this case. The liver tissue is firm and has a waxy appearance--although this is difficult to appreciate in an image.)
21:33, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid1.jpg (This is a gross picture of liver from this case. Note the pale, swollen appearance of this liver.)
20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis5.jpg (This is a special stain for amyloid (Luxol PAS) demonstrating the amyloid (1) and fibrosis (2) in the myocardium. The amyloid is darker purple/magenta and tends to be more amorphous. The fibrosis is pink and more fibrillar.)
20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis4.jpg (This is a higher-power photomicrograph of extracellular amyloid (1) and deposition of amyloid in the vessel wall (2).)
20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis3.jpg (This is a higher-power photomicrograph of the heart tissue from this case. Note the amyloid deposition throughout the myocardium (1) as well as deposition in the wall of the blood vessel (2).)
20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis2.jpg (This is a low power photomicrograph of the heart tissue from this case. At this magnification the structure looks relatively normal.)
20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis1.jpg (This is a gross photograph of section of heart tissue from this case. The tissue was firm and had a waxy texture. If you use your imagination you can see pale yellow areas within this tissue which represent the amyloid deposits.)
18:29, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs6.jpg (This is a karyotype of a patient with Turner syndrome (45, X).)
18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs5.jpg (This is a karyotype of a patient with Klinefelter syndrome (47, XXY).)
18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs4.jpg (FISH is also useful in the diagnosis of other genetic disorders. This is an example of FISH staining on another patient using a probe specific for DiGeorge's disease. The arrow shows that there is a deletion on chromosome 22, which is diagnostic for Di...)
18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs3.jpg (Chromosomes from the chromosome spread are lined up to demonstrate the karyotype. In this case there are three copies of chromosome 21, just as noted in the FISH.)
18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs2.jpg (These cells, obtained by amniocentesis, were cultured and then arrested in metaphase. Nuclei from these cells were isolated and stained to demonstrate the banding pattern of each chromosome. This photograph shows a "chromosome spread." Each chromosome ...)
18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs1.jpg (This is a photomicrograph of cells obtained by amniocentesis that were stained using FISH. The cell in panel 1 was stained with markers specific for the X and Y-chromosomes. The cell in panel 2 was stained with a marker specific for chromosome 18. The ...)
18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease7.jpg (Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.)
18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease6.jpg (This is a gross photograph of a thyroid from a case of nodular goiter.)
18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease5.jpg (This is a high-power photomicrograph of thyroid. Note the papillary projections and the moth-eaten appearance of the colloid. This appearance indicates active absorption of the colloid to form thyroglobulin.)
18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease4.jpg (This is a high-power photomicrograph of thyroid. Note the cellularity of the tissue with marked infolding of the epithelial tissue.)
18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease3.jpg (This is a higher-power photomicrograph of thyroid. The tissue is very cellular and there is little colloid.)
18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease2.jpg (This is a low-power photomicrograph of thyroid tissue from this case. The tissue is very cellular with very little colloid.)

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