Difference between revisions of "IPLab:Lab 4:Thromboembolus"

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(Autopsy Findings)
 
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== Clinical Summary ==
 
== Clinical Summary ==
 
 
This 67-year-old male was hospitalized because of extensive atherosclerotic cardiovascular disease. Following surgery, during which diseased portions of the femoral arteries were bypassed, he developed massive pulmonary embolization and expired.  
 
This 67-year-old male was hospitalized because of extensive atherosclerotic cardiovascular disease. Following surgery, during which diseased portions of the femoral arteries were bypassed, he developed massive pulmonary embolization and expired.  
  
== Autopsy Findings ==
+
At autopsy, thrombi were found in the femoral and iliac veins, as well as in the larger pulmonary arteries.
 
 
At autopsy, thrombi were found in the femoral and iliac veins, as well as in the larger pulmonary arteries.  
 
  
 
== Images ==
 
== Images ==
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File:IPLab4Thromboembolus10.jpg|This is a gross photograph of the fibrous band between the uterus and adjacent tissues. This fibrous scar tissue is probably left over from a previous surgery or an infection. A loop of bowel herniated through the opening produced by this fibrous band and became incarcerated leading to the ischemic necrosis seen in the previous image.  
 
File:IPLab4Thromboembolus10.jpg|This is a gross photograph of the fibrous band between the uterus and adjacent tissues. This fibrous scar tissue is probably left over from a previous surgery or an infection. A loop of bowel herniated through the opening produced by this fibrous band and became incarcerated leading to the ischemic necrosis seen in the previous image.  
 
</gallery>
 
</gallery>
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== Virtual Microscopy ==
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=== Lung: Thromboembolus ===
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<peir-vm>IPLab4Thromboembolus</peir-vm>
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=== Normal Lung ===
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<peir-vm>UAB-Histology-00107</peir-vm>
  
 
== Study Questions ==
 
== Study Questions ==
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* <spoiler text="What are the clinical sequelae of pulmonary thromboemboli?">Most (60-80%) pulmonary thromboemboli are clinically silent. In the remainder of the cases, pulmonary thromboemboli can cause sudden death, acute or chronic cor pulmonale, infarction, or hemorrhage.</spoiler>
 
* <spoiler text="What are the clinical sequelae of pulmonary thromboemboli?">Most (60-80%) pulmonary thromboemboli are clinically silent. In the remainder of the cases, pulmonary thromboemboli can cause sudden death, acute or chronic cor pulmonale, infarction, or hemorrhage.</spoiler>
 
* <spoiler text="What is a paradoxical embolism?">When a venous embolus passes through an interatrial or interventricular septal defect and enters the systemic circulation.</spoiler>
 
* <spoiler text="What is a paradoxical embolism?">When a venous embolus passes through an interatrial or interventricular septal defect and enters the systemic circulation.</spoiler>
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== Additional Resources ==
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=== Reference ===
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* [http://emedicine.medscape.com/article/300901-overview eMedicine Medical Library: Pulmonary Embolism]
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* [http://emedicine.medscape.com/article/1911303-overview eMedicine Medical Library: Deep Venous Thrombosis]
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* [http://emedicine.medscape.com/article/1950759-overview eMedicine Medical Library: Noncoronary Atherosclerosis]
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* [http://www.merckmanuals.com/professional/hematology_and_oncology/thrombotic_disorders/overview_of_thrombotic_disorders.html Merck Manual: Thrombotic Disorders]
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* [http://www.merckmanuals.com/professional/pulmonary_disorders/pulmonary_embolism/pulmonary_embolism.html Merck Manual: Pulmonary Embolism]
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* [http://www.merckmanuals.com/professional/cardiovascular_disorders/peripheral_venous_disorders/deep_venous_thrombosis_dvt.html Merck Manual: Deep Venous Thrombosis]
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=== Journal Articles ===
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* Garg K.  [http://www.ncbi.nlm.nih.gov/pubmed/11813814 CT of pulmonary thromboembolic disease].  ''Radiol Clin North Am'' 2002 Jan;40(1):111-22, ix.
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=== Images ===
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* [{{SERVER}}/library/index.php?/tags/28-thromboembolus PEIR Digital Library: Thromboembolus Images]
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* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#7 WebPath: Pulmonary Pathology]
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== Related IPLab Cases ==
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* [[IPLab:Lab 4:Pulmonary Congestion and Edema|Lab 4: Lung: Pulmonary Congestion and Edema]]
  
 
{{IPLab 4}}
 
{{IPLab 4}}
  
 
[[Category: IPLab:Lab 4]]
 
[[Category: IPLab:Lab 4]]

Latest revision as of 01:59, 24 June 2020

Clinical Summary[edit]

This 67-year-old male was hospitalized because of extensive atherosclerotic cardiovascular disease. Following surgery, during which diseased portions of the femoral arteries were bypassed, he developed massive pulmonary embolization and expired.

At autopsy, thrombi were found in the femoral and iliac veins, as well as in the larger pulmonary arteries.

Images[edit]

Virtual Microscopy[edit]

Lung: Thromboembolus[edit]

Normal Lung[edit]

Study Questions[edit]


Additional Resources[edit]

Reference[edit]

Journal Articles[edit]

Images[edit]

Related IPLab Cases[edit]

A thrombus is a solid mass resulting from the aggregation of blood constituents within the vascular system.

An occlusion is a blockage.