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==Clinical History==
45 year old male with weight loss and jaundice.
==Cytology==
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===Resident Questions===
* <spoiler text="Diagnosis?">__NOGLOSSARY__
* Chronic pancreatits
** Occurs in the 4th and 5th decades
** Strictures of the biliary or pancreatic ducts occurs as well as calcification
</spoiler>
* <spoiler text="What are some of the cytologic features that lead you to the diagnosis?">__NOGLOSSARY__
* Variable cellularity depending on the fibrosis in the specimen, however usually low cellularity
* Smears are polymorphous (ductal cells, acinar cells, macrophages, inflammatory cells, fibrosis, debris, calcification, fat necrosis)
* Ductal cells out number acinar cells (acinar atrophy)
</spoiler>
* <spoiler text="Differential diagnosis?"> __NOGLOSSARY__
* Adenocarcinoma
** Occurs later (6th and 7th decades)
* Pancreatic cancer is often surrounded by a zone of pancreatitis, therefore pancreatits does not exclude malignancy nor does inflammation
</spoiler>
{{Cytologically Yours}}
[[Category:Unknowns]]
