Difference between revisions of "Cytologically Yours: Unknowns: 201401: Case 2"

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(Resident Questions)
 
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==Clinical History==
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52 year old female with a pancreatic head mass.
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==Cytology==
 
==Cytology==
 
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===Resident Questions===
 
===Resident Questions===
* <spoiler text="Diagnosis?">
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* <spoiler text="Diagnosis?">__NOGLOSSARY__
 
* Pancreatic Endocrine Neoplasm
 
* Pancreatic Endocrine Neoplasm
 
** Include Islet cell tumor and pancreatic carcinoid tumors
 
** Include Islet cell tumor and pancreatic carcinoid tumors
** Approximately 5 percent of pancreatic neoplasms
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** Approximately 5% of pancreatic neoplasms
 
** Most commonly seen in both male and female adults between 40-60 years old but can occur at any age
 
** Most commonly seen in both male and female adults between 40-60 years old but can occur at any age
 
** Small (1-5 cm) well circumscribed lesion may look cystic on imaging
 
** Small (1-5 cm) well circumscribed lesion may look cystic on imaging
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** Can be part of Multiple Endocrine Neoplasia-1, von Hipple-Lindau disease, Neurofibromatosis type 1, Tuberous Sclerosis Complex
 
** Can be part of Multiple Endocrine Neoplasia-1, von Hipple-Lindau disease, Neurofibromatosis type 1, Tuberous Sclerosis Complex
 
</spoiler>
 
</spoiler>
* <spoiler text="What are some of the cytologic features that lead you to the diagnosis?">
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* <spoiler text="What are some of the cytologic features that lead you to the diagnosis?">__NOGLOSSARY__
 
* Cellular smear with singly dispersed uniform cells
 
* Cellular smear with singly dispersed uniform cells
 
* Loosely cohesive or discohesive uniform cells
 
* Loosely cohesive or discohesive uniform cells
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* Round/oval bland cells with salt and pepper chromatin
 
* Round/oval bland cells with salt and pepper chromatin
 
</spoiler>
 
</spoiler>
* <spoiler text="Differential diagnosis?">
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* <spoiler text="Differential diagnosis?">__NOGLOSSARY__
 
* Acinar cell carcinoma
 
* Acinar cell carcinoma
 
** Clusters, acinar groups and single cells with abundant granular cytoplasm and prominent nucleoli
 
** Clusters, acinar groups and single cells with abundant granular cytoplasm and prominent nucleoli

Latest revision as of 20:04, 16 January 2014

Clinical History

52 year old female with a pancreatic head mass.

Cytology

Resident Questions