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==Clinical History==
72 year old female with jaundice and a pancreatic mass.
==Cytology==
===Resident Questions===
* <spoiler text="Diagnosis?">__NOGLOSSARY__
* Adenocarcinoma
** Most common malignant tumor of the pancreas
** Accounts for approximately 85% of all pancreatic tumors
** Patients are commonly women in the 6th and 7th decades of life
** Prognosis is poor *** 90% of patients die within a year of diagnosis
** Association with cigarette smoking, high fat diet, and diabetes mellitus
** Triad of weight loss, pain, and jaundice
** Can obstruct the biliary or pancreatic ducts which can cause a double duct sign on imaging and can also cause painless jaundice
</spoiler>
* <spoiler text="What are some of the cytologic features that lead you to the diagnosis?">__NOGLOSSARY__
* Cellular specimen
* Predominantly ductal type cells and sparse/absent acinar cells
* Drunken honeycomb
</spoiler>
* <spoiler text="Differential diagnosis?"> __NOGLOSSARY__
* Chronic pancreatitis
** Occurs in 4th and 5th decades
* The presence of mitotic figures does not support the diagnosis of carcinoma. Mitotic figures can be seen in chronic pancreatitis.
</spoiler>
{{Cytologically Yours}}
[[Category:Unknowns]]
