Difference between revisions of "Cytologically Yours: Unknowns: 201311: Case 2"

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==Clinical History==
 
==Clinical History==
48 year old male with a solid thyroid nodule on ultrasound.
+
48 year old male with a 3.5 cm thyroid nodule on ultrasound.
  
 
==Cytology==
 
==Cytology==
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CytologicallyYoursUnknowns201311-2-01.jpg
 
CytologicallyYoursUnknowns201311-2-01.jpg
 
CytologicallyYoursUnknowns201311-2-02.jpg
 
CytologicallyYoursUnknowns201311-2-02.jpg
 +
CytologicallyYoursUnknowns201311-2-03.jpg
  
 
</gallery>
 
</gallery>
 
  
 
===Resident Questions===
 
===Resident Questions===
 
* <spoiler text="Diagnosis?">
 
* <spoiler text="Diagnosis?">
* Follicular neoplasm </spoiler?">
+
* Follicular neoplasm). </spoiler>
* <spoiler text="What are the most common molecular associations with follicular neoplasms/ follicular carcinoma?">
+
* <spoiler text="What are the most common molecular associations?">
* Ras mutations in 48%.
+
* Ras mutation in 49%.  
* PAX8-PPAR gamma rearrangement in 36%.
+
* PAX8-PPAR gamma rearrangements in 36%.
 +
</spoiler>
  
</spoiler>
+
==Cytologic Features==
 +
* Microfollicles and trabeculae
 +
* Cellular crowding
 +
* Cellular aspirate
 +
* Little to absent colloid
 +
* Monotony

Latest revision as of 19:50, 10 January 2014

Clinical History

48 year old male with a 3.5 cm thyroid nodule on ultrasound.

Cytology

Resident Questions


Cytologic Features

  • Microfollicles and trabeculae
  • Cellular crowding
  • Cellular aspirate
  • Little to absent colloid
  • Monotony