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  • 21:33, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid1.jpg (This is a gross picture of liver from this case. Note the pale, swollen appearance of this liver.)
  • 20:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN1.jpg (This is a low-power photomicrograph of a saggital section of end stage chronic glomerulonephritis (GN). Note the marked thinning of the cortex (arrow).)
  • 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN10.jpg (For comparison this is an immunofluorescent photomicrograph of a glomerulus from a patient with Goodpasture's syndrome. The linear (arrows) immunofluorescence is characteristic of Goodpasture's syndrome.)
  • 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN9.jpg (This electron micrograph demonstrates scattered subepithelial dense deposits (arrows) and a polymorphonuclear leukocyte in the lumen.)
  • 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN8.jpg (This immunofluorescent photomicrograph of a glomerulus from a case of acute poststreptococcal glomerulonephritis shows a granular immunofluorescence pattern consistent with immune complex disease. The primary antibody used for this staining was specifi...)
  • 20:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN7.jpg (This is a photomicrograph of a glomerulus from another case with acute poststreptococcal glomerulonephritis. In this case the immune complex glomerular disease is ongoing with necrosis and accumulation of neutrophils in the glomerulus.)
  • 20:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN6.jpg (This is an electron micrograph of subepithelial granular electron dense deposits (arrows) which correspond to the granular immunofluorescence seen in the previous image.)
  • 20:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN5.jpg (This is an immunofluorescent photomicrograph of granular membranous immunofluorescence (immune complex disease). The antibody used for these studies was specific for IgG.)
  • 20:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN4.jpg (This is a photomicrograph of interstitial and vascular lesions in end stage renal disease.)
  • 20:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN3.jpg (This is a higher-power photomicrograph of hyalinized glomeruli (1) and glomeruli with thickened basement membranes (2).)
  • 20:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN2.jpg (This is a higher-power photomicrograph of hyalinized glomeruli (arrows) and glomeruli with thick basement membranes.)
  • 20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis5.jpg (This is a special stain for amyloid (Luxol PAS) demonstrating the amyloid (1) and fibrosis (2) in the myocardium. The amyloid is darker purple/magenta and tends to be more amorphous. The fibrosis is pink and more fibrillar.)
  • 20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis4.jpg (This is a higher-power photomicrograph of extracellular amyloid (1) and deposition of amyloid in the vessel wall (2).)
  • 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis3.jpg (This is a higher-power photomicrograph of the heart tissue from this case. Note the amyloid deposition throughout the myocardium (1) as well as deposition in the wall of the blood vessel (2).)
  • 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis2.jpg (This is a low power photomicrograph of the heart tissue from this case. At this magnification the structure looks relatively normal.)
  • 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis1.jpg (This is a gross photograph of section of heart tissue from this case. The tissue was firm and had a waxy texture. If you use your imagination you can see pale yellow areas within this tissue which represent the amyloid deposits.)
  • 20:14, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB6.jpg (This is a high-power (oil immersion) photomicrograph of granuloma stained with an acid-fast stain. Mycobacterium tuberculosis bacilli stain red.)
  • 20:13, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB5.jpg (High-power photomicrograph of a TB granuloma with multinucleated giant cells adjacent to an area of caseous necrosis (to the left).)
  • 20:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB4.jpg (This is a higher-power photomicrograph of a TB granuloma. The area of caseous necrosis is on the left side of the image, there are multinucleated giant cells and epithelioid macrophages throughout the remainder of the tissue.)
  • 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB3.jpg (This is a higher-power photomicrograph of a TB granuloma. Note the eosinophilic material in the center of this granuloma (caseous necrosis) and the epithelioid macrophages and giant cells around the periphery.)
  • 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB2.jpg (This is a low-power photomicrograph of lung tissue with multiple circumscribed nodules - granulomas (arrows).)
  • 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB1.jpg (This is a photograph of a section of lung with an apical lesion. This lesion represents an old healed lesion from Mycobacterium tuberculosis infection.)
  • 19:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma5.jpg (This is a gross photograph of the heart from this case. There is thickening of the left ventricular wall and some thickening of the right ventricle as well.)
  • 19:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma4.jpg (This is a closer view of the cut section of lung from this patient showing the extensive fibrosis and the severe emphysematous change.)
  • 19:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma3.jpg (This is a closer view of the cut section of lung from this patient. Note the extensive fibrosis and the severe emphysematous changes.)
  • 19:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma2.jpg (This is a gross photograph of a cut section of one lung from this patient. Note the extensive fibrosis lower lobe (arrows).)
  • 19:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma1.jpg (This is a gross photograph of cut section of the lungs from this patient. Note the extensive fibrosis of the lung parenchyma.)
  • 18:00, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN13.jpg (This is a high-power photomicrograph of the affected vessel in the heart. The vessel lumen is completely occluded.)
  • 18:00, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN12.jpg (This is a higher-power photomicrograph of the affected vessels in the heart (arrows). There are areas of fibrosis (old infarcts) in the myocardium adjacent to these affected vessels.)
  • 17:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN11.jpg (This is a low-power photomicrograph of the heart. There are areas of fibrosis in the myocardium (arrows). Note that the large epicardial coronary artery is normal.)
  • 17:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN10.jpg (This is a higher-power photomicrograph of the affected vessel from the previous image. The vessel wall is infiltrated with inflammatory cells and the vessel lumen is completely occluded (arrow).)
  • 17:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN9.jpg (This is a low-power photomicrograph of the adrenal gland. There is an area of necrosis in the adrenal (1) and an affected vessel adjacent to the adrenal (2).)
  • 17:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN8.jpg (This is a high-power photomicrograph of a small vessel with a rim of fibrinoid necrosis (arrow).)
  • 17:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN7.jpg (This is a high-power photomicrograph of the vessel wall. There is hemorrhage and infiltration with inflammatory cells--primarily neutrophils (arrows).)
  • 17:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN6.jpg (his is another example of a mesenteric artery from this case. There is a marked inflammatory cell response surrounding this vessel, fresh hemorrhage (1), and thrombotic material (2).)
  • 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN5.jpg (This is a higher-power photomicrograph of this mesenteric vessel. Note the thrombotic material occluding the vessel (arrows) and the inflammatory cell infiltrate in the wall of the vessel and in the surrounding adventitia.)
  • 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN4.jpg (This is a low-power photomicrograph of a mesenteric vessel from this case of polyarteritis nodosa (arrow). The vessel is completely occluded by thrombotic material and the vessel wall is infiltrated with inflammatory cells.)
  • 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN3.jpg (This angiogram of the kidneys demonstrates numerous aneurysmal dilatations in the renal circulation (arrows).)
  • 17:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN2.jpg (This angiogram of the liver also demonstrates numerous aneurysms throughout the hepatic circulation (arrows).)
  • 17:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN1.jpg (This angiogram of the abdominal viscera demonstrates numerous aneurysms throughout the mesenteric circulation (arrows).)
  • 17:47, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto9.jpg (This high-power photomicrograph shows more clearly the lymphocytes and plasma cells surrounding the thyroid gland epithelium. Large, eosinophilic, degenerating thyroid gland cells (Hurthle cells) can be seen in this section (arrows).)
  • 17:47, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto8.jpg (This is a high-power photomicrograph showing the lymphocytes and plasma cells surrounding the thyroid gland epithelium.)
  • 17:46, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto7.jpg (This is a high-power photomicrograph showing the inflammatory cells infiltrating into the residual thyroid tissue (arrows).)
  • 17:46, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto6.jpg (This is another higher-power photomicrograph of thyroid from this case showing the inflammatory cells and the residual thyroid tissue.)
  • 17:44, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto5.jpg (This is a higher-power photomicrograph of thyroid from this case showing the inflammatory cells and the residual thyroid tissue.)
  • 17:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto4.jpg (This is another view of thyroid gland filled with inflammatory cells forming germinal centers (arrows).)
  • 17:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto3.jpg (This is a higher-power photomicrograph of thyroid from this case. Note the large number of blue-staining inflammatory cells in this tissue. These cells appear to be forming germinal centers. Some residual thyroid gland tissue can be seen in this sectio...)
  • 17:42, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto2.jpg (This is a low-power photomicrograph of thyroid from this case. Note that the tissue is more cellular than one would expect and there does not appear to be normal colloid-filled blue spaces in this gland.)
  • 17:42, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto1.jpg (This is a gross photograph of thyroid gland taken at autopsy. The gland is only slightly enlarged and has a firm texture.)
  • 15:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM7.jpg (This is a photomicrograph of kidney with a focal exudative lesion in a glomerulus (arrow) and sclerosis, interstitial fibrosis, and congestion.)
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