Cytologically Yours: Unknowns: 201310: Case 3

Clinical History

69 year old male with a right upper lobe lung mass. The patient has a history of smoking, melanoma, multiple basal cell carcinomas, and squamous cell carcinomas. The specimen is a bronchial brushing.

Cytology

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Resident Question

• List 3 differential diagnosis

• Adenocarcinoma
• Lymphoma
• Melanoma
• Neuroendocrine
• Plasma cell neoplasm
• Squamous cell carcinoma

Immunohistochemistry

• LCA

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• MOC31

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• Cytokeratin Cocktail

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• 34BE12

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• HMB45

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Resident Question

• Diagnosis

Melanoma