IPLab:Lab 7:Bronchogenic Carcinoma

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Contents

Clinical Summary

This 55-year-old white male had a long history of emphysemaPulmonary emphysema is a condition in which the air spaces distal to the terminal bronchioles are permanently increased in size due to either destruction of the wall or alveolar dilatation. and a 60-70 pack-yearA pack-year denotes smoking one pack of cigarettes per day for one year. smoking history. He was in his usual state of health until about one month before admission, at which time he developed increasing dyspnea on exertion. At the same time, his sputum increased from two tablespoons to half a cup of yellow blood-streaked sputum a day. Chest x-ray showed a right hilar mass. Sputum cytology revealed abnormal cells that were "positive for malignancy." He later developed pneumoniaIn alcoholics, aspiration pneumonia is common--bacteria enter the lung via aspiration of gastric contents. and fever. The patient expired soon thereafter.

Autopsy Findings

Significant findings included advanced carcinoma of the right main stem bronchus with extension across the carina to produce obstruction of the left main stem bronchus. There was left lower lobe pneumoniaIn alcoholics, aspiration pneumonia is common--bacteria enter the lung via aspiration of gastric contents. and left upper lobe atelectasisAtelectasis is the collapse of an airway and lung, regardless of the cause, resulting in reduced or absent gas exchange.. Extensive metastases were present in regional lymph nodes as well as the pericardium, left atrium, and right kidney.

Images

Virtual Microscopy

Study Questions


Additional Resources

Reference

Journal Articles

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