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== Clinical Summary ==
Six days before his death, this 31-year-old white male became acutely ill with fever followed by an ascending paralysis which began in his feet. Three days later he was hospitalized because of difficulty in breathing. A lumbar puncture was performed and the patient's spinal fluid contained increased protein and polymorphonuclear leukocytes (4.30 PMNs/cmmmm³). He died on the third hospital day.
== Autopsy Findings ==
File:IPLab8Polio5.jpg|This is another high-power photomicrograph of the anterior horn with inflammatory cell infiltrate and total loss of neurons.
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== Virtual Microscopy ==
=== Poliomyelitis ===
<peir-vm>IPLab8Polio</peir-vm>
=== Normal Spinal Cord ===
<peir-vm>IPLab8Polio-Normal_cord</peir-vm>
== Study Questions ==
=== Journal Articles ===
* Alexander L, Birkhead G, Guerra F, Helms C, Hinman A, Katz S, LeBaron CW, Modlin J, Murphy TV; National Vaccine Advisory Committee-Advisory Committee on Immunization Practices Joint Working Group; Centers for Disease Control and Prevention. [http://www.ncbi.nlm.nih.gov/pubmed/15583093 Ensuring preparedness for potential poliomyelitis outbreaks: recommendations for the US poliovirus vaccine stockpile from the National Vaccine Advisory Committee (NVAC) and the Advisory Committee on Immunization Practices (ACIP)]. ''Arch Pediatr Adolesc Med'' 2004 Dec;158(12):1106-12.
=== Images ===
* [{{SERVER}}/library/index.php?/tags/2149-polio PEIR Digital Library: Polio Images] == Related IPLab Cases ==* [http://library.med.utah.edu/WebPath/CNSHTML/CNSIDX.html#7 WebPath: CNS Pathology: Acquired and Congenital Degenerative Diseases]
{{IPLab 8}}
[[Category: IPLab:Lab 8]]