User contributions
19 August 2013
File:IPLab5Neurofibromatosis1.jpg
This photograph, taken at autopsy, demonstrates the distribution of neurofibromas on the skin of this patient.
IPLab:Lab 2:Fatty Change and Cirrhosis
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IPLab:Lab 2:Fatty Change and Cirrhosis
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File:IPLab2FattyChange12.jpg
This is a cut surface of the same tissue seen in the previous slide. Note the marked nodular pattern. The paler-staining areas between the round nodules represent fibrous connective tissue.
IPLab:Lab 2:Fatty Change and Cirrhosis
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab2FattyChange1.jpg|This gross photograph of liver tissue illustrates the yellowish color of the liver parenchyma..."
File:IPLab2FattyChange11.jpg
This gross photograph of liver demonstrates severe nodular cirrhosis. Note the extensive scarring of the capsule and the nodular projections of tissue through the uncut capsule in this tissue. The green color is due to the accumulation of bile pigment.
File:IPLab2FattyChange10.jpg
This is a low-power photomicrograph of liver stained with a trichrome stain. In this section, connective tissue stains green (arrows) and hepatic parenchymal cells are red. Note that many of the parenchymal cells have clear spaces indicating fatty dege...
File:IPLab2FattyChange9.jpg
This photomicrograph of the liver is from another patient with a history of alcohol use. There are some clear vacuoles indicating fat droplets (1) and there are numerous red-staining granular deposits within the cytoplasm of hepatocytes (2)--this is al...
File:IPLab2FattyChange8.jpg
An oil red O stain for fat was performed on a frozen section of this liver tissue. The red droplets represent fat in the tissue which is typical of fatty degeneration in the liver. By using frozen sections the tissues do not have to be dehydrated throu...
File:IPLab2FattyChange7.jpg
A high-power photomicrograph of the liver parenchyma shows that each individual liver cell is filled with a large, clear droplet which represents the space remaining after lipid was dissolved by the dehydration procedure used to embed the tissue. '''No...
File:IPLab2FattyChange6.jpg
Another view at the same power illustrates the proliferation of bile ducts in the interlobular and perichordal regions (arrows).
File:IPLab2FattyChange5.jpg
This higher-power photomicrograph of the centrilobular area gives the appearance of fatty tissue, as indicated by many empty spaces. Very few normal liver cells can be seen in this slide. A few more normal-appearing hepatocytes are present at the left ...
File:IPLab2FattyChange4.jpg
A higher-power photomicrograph illustrates more clearly the inflammatory cells (arrows) around the portal areas.
File:IPLab2FattyChange3.jpg
Another low-power photomicrograph illustrates again the pale, washed-out appearance of this tissue. Notice the numerous holes throughout the tissue. There are accumulations of inflammatory cells (arrows) around portal tracts.
File:IPLab2FattyChange2.jpg
This low-power photomicrograph of liver illustrates a very pale-staining section with a uniform appearance throughout the section.
File:IPLab2FattyChange1.jpg
This gross photograph of liver tissue illustrates the yellowish color of the liver parenchyma. The yellow color indicates high fat content in this tissue. Compare this with the normal dark red color of liver.
File:IPLab2Calcification2.jpg
This low-power photomicrograph of the patient's lung illustrates large, open alveolar spaces. The pleural surface is the curved surface at the top.
IPLab:Lab 2:Metastatic Calcification
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab2Calcification1.jpg|This is a gross photograph of the cut section of the patient's lung showing evidence of sev..."
File:IPLab2Calcification8.jpg
This gross photograph affords a closer view of the same aortic valve. Note the nodularity and thickening of this valve due to fibrosis and dystrophic calcification.
File:IPLab2Calcification7.jpg
A closer view of this same aortic valve (arrow) illustrates the nodularity and thickening of this valve. This valve would be extremely stiff and almost entirely immobile. This particular example of dystrophic calcification is associated with a degenera...
File:IPLab2Calcification6.jpg
Metastatic calcification is only one of two forms of pathologic calcification. Unlike metastatic calcification, dystrophic calcification does not require an increase in serum calcium levels. This is a gross specimen of a heart with dystrophic calcifica...
File:IPLab2Calcification5.jpg
This photomicrograph demonstrates pulmonary alveoli with extensive calcium depositions (1) in the septa and protein accumulations (2) in the alveoli.
File:IPLab2Calcification4.jpg
This high-power photomicrograph of a blood vessel shows calcium deposits in the vascular wall (1) and proteinaceous material (2) (from edema) within some of the alveoli. The smooth muscle in the vessel wall has been almost completely replaced by calciu...
File:IPLab2Calcification3.jpg
A higher-power photomicrograph shows a blood vessel cut in longitudinal section (1). Several of the alveoli are filled with a pink-staining proteinaceous fluid (2) indicative of pulmonary edema. The alveolar septa and the wall of the blood vessel have ...
File:IPLab2Calcification1.jpg
This is a gross photograph of the cut section of the patient's lung showing evidence of severe metastatic calcification. The lung tissue has a rough, firm appearance with open airways.
IPLab:Lab 2:Atrophy
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File:IPLab2Atrophy10.jpg
This gross photograph shows a normal brain (left) and a brain from a geriatric patient (right). Note the decreased size, the narrowed gyri, and the widened sulci of the brain from this octogenarian. What is the cause of atrophy in this case?
File:IPLab2Atrophy9.jpg
The two kidneys in this slide are from the same patient. One kidney (1) is relatively normal, although increased in size due to compensatory hypertrophy. The other kidney (2) is very small with only rudimentary nodules of renal parenchyma. This kidney ...
File:IPLab2Atrophy8.jpg
These kidneys were removed from a patient who had blockage of one ureter leading to increased pressure in the renal pelvis. The increased pressure produced hydronephrosis (arrow) in one kidney. What is the cause of atrophy in this case?
File:IPLab2Atrophy7.jpg
In this gross photograph of kidneys and the abdominal aorta, there is narrowing of the left renal artery at its ostium from the aorta. This atherosclerotic narrowing of the renal artery causes reduced blood pressure in the kidney whose artery is affect...
File:IPLab2Atrophy6.jpg
In this slide, the atrophy of the tubules is extending to include the Rete testes (arrow) as well.
File:IPLab2Atrophy5.jpg
Peter Anderson uploaded a new version of "File:IPLab2Atrophy5.jpg": A seminiferous tubule is shown on the left containing remnants of spermatocytes (1). There are no mature sperm present. On the right-hand portion of the slide are remnants o
File:IPLab2Atrophy4.jpg
This is a higher-power photomicrograph indicating loss of testicular parenchymal tissue. There are very few recognizable spermatic cells in this tissue. The cluster of cells in the upper right is a focus of interstitial or Leydig cells (arrow). These c...
File:IPLab2Atrophy5.jpg
This is a higher-power photomicrograph indicating loss of testicular parenchymal tissue. There are very few recognizable spermatic cells in this tissue. The cluster of cells in the upper right is a focus of interstitial or Leydig cells (arrow). These c...
File:IPLab2Atrophy3.jpg
This is a higher-power photomicrograph of an atrophic testis. In this section there are seminiferous tubules with viable cells (1) although there are no visible spermatocytes. Other seminiferous tubules are completely acellular and have a pale pink hya...
File:IPLab2Atrophy2.jpg
This is a low-power photomicrograph of an atrophic testis. Attached to the testis are several vessels (arrow) which are part of the epididymis and the vas deferens.
File:IPLab2Atrophy1.jpg
This is a gross photograph of an atrophied testis (arrows).
IPLab:Lab 2:Atrophy
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab2Atrophy1.jpg|This is a gross photograph of an atrophied testis (arrows). File:IPLab2Atrophy2.jpg| File:IPLab2A..."
File:IPLab2Metaplasia2.jpg
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IPLab:Lab 2:Metaplasia
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IPLab:Lab 2:Metaplasia
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab2Metaplasia1.jpg|This is a low-power photomicrograph showing the full cortical and medullary thickness of the k..."
File:IPLab2Metaplasia7.jpg
This is a photomicrograph of the trachea from a smoker. Note that the columnar ciliated epithelium has been replaced by squamous epithelium.
File:IPLab2Metaplasia6.jpg
A high-power photomicrograph of the squamous epithelium shows inflammatory cells in the subepithelial tissue and the formation of keratinized epithelium (arrows).
File:IPLab2Metaplasia5.jpg
In areas adjacent to the normal transitional epithelium, there are areas of epithelium (arrows) where the epithelial cells have the character of normal squamous epithelium as found in the dermis. However, squamous epithelium is not normal in the renal ...
File:IPLab2Metaplasia4.jpg
This is a higher-power photomicrograph of the junction of normal epithelium (1) with hyperplastic transitional epithelium (2).
File:IPLab2Metaplasia3.jpg
A higher-power view shows the junction of normal epithelium (1) with hyperplastic transitional epithelium (2). Note the inflammatory cells in the subepithelial tissue.
File:IPLab2Metaplasia2.jpg
his high-power photomicrograph demonstrates the transitional epithelium lining the renal calyx (1) and the junction (transition zone) to a thicker hyperplastic epithelium (2). Note the inflammatory cells and increased vascular response in the stromal t...
File:IPLab2Metaplasia1.jpg
This is a low-power photomicrograph showing the full cortical and medullary thickness of the kidney. Note that there is a dilated calyx containing some red blood cells in the center of the section (arrow). The cortex is markedly thin and has severe les...
IPLab:Lab 2:Hyperplasia
Created page with "== Images == <gallery heights="250px" widths="250px"> File:IPLab2Hyperplasia1.jpg|This photograph shows the autopsy specimen from this patient. Included are kidneys (1), urete..."
File:IPLab2Hyperplasia9.jpg
This kidney was removed from another autopsy patient who had prostatic hyperplasia resulting in marked urinary retention and back-flow of urine from the bladder into the ureters and renal pelvis. The increased pressure inside the renal pelvis resulted ...