IPLab:Lab 9:Bacterial Meningitis

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Clinical Summary[edit]

This 45-year-old white female with a history of psychiatric illness sustained self-inflicted third degree burns over 49% of her body surface. After initially doing well under treatment, she developed severe respiratory distress and became comatose. Antemortem blood cultures were positive for Pseudomonas aeruginosa.

Autopsy Findings[edit]

At autopsy the principal findings were in the lungs and brain. Bronchopneumonia was present in all lobes of both lungs. The brain weighed 1450 grams and the leptomeninges contained a thick yellow purulent exudate most prominent over the frontoparietal areas and at the base of the brain.

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An average adult female brain weighs 1400 grams (range: 1100 to 1700 grams).