IPLab:Lab 2:Atrophy: Difference between revisions
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Prostatic growth is dependent upon testicular androgens. Estrogen therapy leads to inhibition of pituitary gonadotropin and/or ACTH production which causes androgen deprivation. Newer drugs use specific testosterone receptor blocking mechanisms to regress prostate hyperplasia and prostate cancer.</spoiler> | Prostatic growth is dependent upon testicular androgens. Estrogen therapy leads to inhibition of pituitary gonadotropin and/or ACTH production which causes androgen deprivation. Newer drugs use specific testosterone receptor blocking mechanisms to regress prostate hyperplasia and prostate cancer.</spoiler> | ||
* <spoiler text="There appears to be an increase in the number of interstitial cells. Is there such a thing as Leydig cell hyperplasia?">No. The Leydig cells appear more prominent due to the paucity of germ cells.</spoiler> | * <spoiler text="There appears to be an increase in the number of interstitial cells. Is there such a thing as Leydig cell hyperplasia?">No. The Leydig cells appear more prominent due to the paucity of germ cells.</spoiler> | ||
== Additional Resources == | |||
=== Reference === | |||
* [http://www.cancer.gov/cancertopics/pdq/treatment/prostate/HealthProfessional/page3 National Cancer Institute: Prostate Cancer Treatment] | |||
* [http://emedicine.medscape.com/article/457394-overview eMedicine Medical Library: Prostate-Specific Antigen] | |||
* [http://emedicine.medscape.com/article/1967731-overview eMedicine Medical Library: Prostate Cancer] | |||
* [http://www.merckmanuals.com/professional/genitourinary_disorders/genitourinary_cancer/prostate_cancer.html Merck Manual: Prostate Cancer] | |||
=== Journal Articles === | |||
* van Leenders GJ, Schalken JA. [http://www.ncbi.nlm.nih.gov/pubmed/11589668 Stem cell differentiation within the human prostate epithelium: implications for prostate carcinogenesis]. ''BJU Int'' 2001 Sep;88 Suppl 2:35-42; discussion 49-50. | |||
=== Images === | |||
* [http://peir.dnsdynamic.com/library/index.php?/tags/146-prostate/219-adenocarcinoma PEIR Digital Library: Prostatic Adenocarcinoma Images] | |||
* [http://library.med.utah.edu/WebPath/MALEHTML/MALEIDX.html WebPath: Male Genital Pathology Images] | |||
{{IPLab 2}} | {{IPLab 2}} | ||
[[Category: IPLab:Lab 2]] | [[Category: IPLab:Lab 2]] | ||