CRP-33: Difference between revisions - Pathology Education Instructional Resource

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'''CRP-33'''

==Clinical History==

Status post cadaveric transplant 15 months ago. Creatinine 3.0.

==Gross Description:==

==Gross Description==

Received in transport media is one core measuring 10 mm in length and 0.5 mm in diameter. It is entirely submitted for light microscopy.

==Pathology==

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<peir-vm>specialcrp/CRP-033_PASH</peir-vm>

<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy.</div>

<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy</div>

==Microscopic Description:==

==Microscopic Description==

===Light Microscopy~~:===~~

===Light Microscopy===

The specimen consists of a fragment of renal cortex with a small portion of capsule on one end. There are sixteen glomeruli in the three levels examined. Three of these area obsolete, but the remainder are similar and show essentially normal morphology. There is mild patchy interstitial fibrosis with corresponding focal mild tubular atrophy. Occasional small collections of lymphocytes are present in the more fibrotic areas, and examples of mild tubulitis are identified in all three levels. However, the degree of tubulitis is relatively mild, with only two or three lymphocytes generally identified per tubular cross-section. The arterioles and small arteries show minimal intimal thickening, but they are otherwise unremarkable.

~~===Immunofluorescence:===~~

~~===Electron Microscopy:~~===

</div></div>

Kidney, transplant, needle biopsy·- Very mild acute interstitial rejection (Banff borderline).

These findings are most consistent with mild acute interstitial rejection. Overall, the tubulointerstitial preservation is quite good, and there are no significant pathologic changes in the glomeruli or vessels.

</spoiler>

@@ Line 1: / Line 1: @@
 '''CRP-33'''
 ==Clinical History==
+Status post cadaveric transplant 15 months ago. Creatinine 3.0.
-==Gross Description:==
+==Gross Description==
+Received in transport media is one core measuring 10 mm in length and 0.5 mm in diameter.  It is entirely submitted for light microscopy.
 ==Pathology==
@@ Line 10: / Line 12: @@
 <peir-vm>specialcrp/CRP-033_PASH</peir-vm>
-<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy.</div>
+<div class="usermessage mw-customtoggle-diagnosis" style="cursor:pointer"> Microscopic Description, Immunofluorescence, and Electron Microscopy</div>
 <div class="mw-collapsible mw-collapsed" id="mw-customcollapsible-diagnosis">
 <div class="mw-collapsible-content">
-==Microscopic Description:==
+==Microscopic Description==
-===Light Microscopy:===
+===Light Microscopy===
+The specimen consists of a fragment of renal cortex with a small portion of capsule on one end.  There are sixteen glomeruli in the three levels examined.  Three of these area obsolete, but the remainder are similar and show essentially normal morphology.  There is mild patchy interstitial fibrosis with corresponding focal mild tubular atrophy.  Occasional small collections of lymphocytes are present in the more fibrotic areas, and examples of mild tubulitis are identified in all three levels.  However, the degree of tubulitis is relatively mild, with only two or three lymphocytes generally identified per tubular cross-section.  The arterioles and small arteries show minimal intimal thickening, but they are otherwise unremarkable.
-===Immunofluorescence:===
-===Electron Microscopy:===
 </div></div>
 <spoiler text="Diagnosis and Comments">
+Kidney, transplant, needle biopsy·- Very mild acute interstitial rejection (Banff borderline).
+These findings are most consistent with mild acute interstitial rejection.  Overall, the tubulointerstitial preservation is quite good, and there are no significant pathologic changes in the glomeruli or vessels.
 </spoiler>