IPLab:Lab 4:Thromboembolus: Difference between revisions - Pathology Education Instructional Resource

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== Clinical Summary ==

This 67-year-old male was hospitalized because of extensive atherosclerotic cardiovascular disease. Following surgery, during which diseased portions of the femoral arteries were bypassed, he developed massive pulmonary embolization and expired.

~~== Autopsy Findings ==~~

At autopsy, thrombi were found in the femoral and iliac veins, as well as in the larger pulmonary arteries.

== Images ==

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File:IPLab4Thromboembolus10.jpg|This is a gross photograph of the fibrous band between the uterus and adjacent tissues. This fibrous scar tissue is probably left over from a previous surgery or an infection. A loop of bowel herniated through the opening produced by this fibrous band and became incarcerated leading to the ischemic necrosis seen in the previous image.

</gallery>

== Virtual Microscopy ==

=== Lung: Thromboembolus ===

<peir-vm>IPLab4Thromboembolus</peir-vm>

=== Normal Lung ===

<peir-vm>UAB-Histology-00107</peir-vm>

== Study Questions ==

* <spoiler text="What are the common sources for pulmonary thromboemboli?">Large deep veins of the lower legs: popliteal, femoral, and iliac veins.</spoiler>

* <spoiler text="What are the clinical sequelae of pulmonary thromboemboli?">Most (60-80%) pulmonary thromboemboli are clinically silent. In the remainder of the cases, pulmonary thromboemboli can cause sudden death, acute or chronic cor pulmonale, infarction, or hemorrhage.</spoiler>

* <spoiler text="What is a paradoxical embolism?">When a venous embolus passes through an interatrial or interventricular septal defect and enters the systemic circulation.</spoiler>

== Additional Resources ==

=== Reference ===

* [http://emedicine.medscape.com/article/300901-overview eMedicine Medical Library: Pulmonary Embolism]

* [http://emedicine.medscape.com/article/1911303-overview eMedicine Medical Library: Deep Venous Thrombosis]

* [http://emedicine.medscape.com/article/1950759-overview eMedicine Medical Library: Noncoronary Atherosclerosis]

* [http://www.merckmanuals.com/professional/hematology_and_oncology/thrombotic_disorders/overview_of_thrombotic_disorders.html Merck Manual: Thrombotic Disorders]

* [http://www.merckmanuals.com/professional/pulmonary_disorders/pulmonary_embolism/pulmonary_embolism.html Merck Manual: Pulmonary Embolism]

* [http://www.merckmanuals.com/professional/cardiovascular_disorders/peripheral_venous_disorders/deep_venous_thrombosis_dvt.html Merck Manual: Deep Venous Thrombosis]

=== Journal Articles ===

* Garg K. [http://www.ncbi.nlm.nih.gov/pubmed/11813814 CT of pulmonary thromboembolic disease]. ''Radiol Clin North Am'' 2002 Jan;40(1):111-22, ix.

=== Images ===

* [{{SERVER}}/library/index.php?/tags/28-thromboembolus PEIR Digital Library: Thromboembolus Images]

* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#7 WebPath: Pulmonary Pathology]

== Related IPLab Cases ==

* [[IPLab:Lab 4:Pulmonary Congestion and Edema|Lab 4: Lung: Pulmonary Congestion and Edema]]

[[Category: IPLab:Lab 4]]

@@ Line 1: / Line 1: @@
 == Clinical Summary ==
 This 67-year-old male was hospitalized because of extensive atherosclerotic cardiovascular disease. Following surgery, during which diseased portions of the femoral arteries were bypassed, he developed massive pulmonary embolization and expired.
-== Autopsy Findings ==
+At autopsy, thrombi were found in the femoral and iliac veins, as well as in the larger pulmonary arteries.
-At autopsy, thrombi were found in the femoral and iliac veins, as well as in the larger pulmonary arteries.
 == Images ==
@@ Line 20: / Line 17: @@
 File:IPLab4Thromboembolus10.jpg|This is a gross photograph of the fibrous band between the uterus and adjacent tissues. This fibrous scar tissue is probably left over from a previous surgery or an infection. A loop of bowel herniated through the opening produced by this fibrous band and became incarcerated leading to the ischemic necrosis seen in the previous image.
 </gallery>
+== Virtual Microscopy ==
+=== Lung: Thromboembolus ===
+<peir-vm>IPLab4Thromboembolus</peir-vm>
+=== Normal Lung ===
+<peir-vm>UAB-Histology-00107</peir-vm>
+== Study Questions ==
+* <spoiler text="What are the common sources for pulmonary thromboemboli?">Large deep veins of the lower legs: popliteal, femoral, and iliac veins.</spoiler>
+* <spoiler text="What are the clinical sequelae of pulmonary thromboemboli?">Most (60-80%) pulmonary thromboemboli are clinically silent. In the remainder of the cases, pulmonary thromboemboli can cause sudden death, acute or chronic cor pulmonale, infarction, or hemorrhage.</spoiler>
+* <spoiler text="What is a paradoxical embolism?">When a venous embolus passes through an interatrial or interventricular septal defect and enters the systemic circulation.</spoiler>
+== Additional Resources ==
+=== Reference ===
+* [http://emedicine.medscape.com/article/300901-overview eMedicine Medical Library: Pulmonary Embolism]
+* [http://emedicine.medscape.com/article/1911303-overview eMedicine Medical Library: Deep Venous Thrombosis]
+* [http://emedicine.medscape.com/article/1950759-overview eMedicine Medical Library: Noncoronary Atherosclerosis]
+* [http://www.merckmanuals.com/professional/hematology_and_oncology/thrombotic_disorders/overview_of_thrombotic_disorders.html Merck Manual: Thrombotic Disorders]
+* [http://www.merckmanuals.com/professional/pulmonary_disorders/pulmonary_embolism/pulmonary_embolism.html Merck Manual: Pulmonary Embolism]
+* [http://www.merckmanuals.com/professional/cardiovascular_disorders/peripheral_venous_disorders/deep_venous_thrombosis_dvt.html Merck Manual: Deep Venous Thrombosis]
+=== Journal Articles ===
+* Garg K.  [http://www.ncbi.nlm.nih.gov/pubmed/11813814 CT of pulmonary thromboembolic disease].  ''Radiol Clin North Am'' 2002 Jan;40(1):111-22, ix.
+=== Images ===
+* [{{SERVER}}/library/index.php?/tags/28-thromboembolus PEIR Digital Library: Thromboembolus Images]
+* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#7 WebPath: Pulmonary Pathology]
+== Related IPLab Cases ==
+* [[IPLab:Lab 4:Pulmonary Congestion and Edema|Lab 4: Lung: Pulmonary Congestion and Edema]]
 {{IPLab 4}}
 [[Category: IPLab:Lab 4]]