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IPLab:Lab 2:Metastatic Calcification

1,181 bytes added, 20:10, 19 June 2020
Autopsy Findings
== Clinical Summary ==
This 47-year-old woman diagnosed with metastatic carcinoma of the breast was also found to have severe hypercalcemia. She developed metastatic calcification which was most prominent in the kidneys and lungs. The patient was provided hospice care and died of respiratory failure.
== Autopsy Findings ==In addition to the metastatic breast cancer, important gross findings at autopsy included lungs that were gritty and firm and which weighed 1330 grams. The patient's parathyroid glands were normal (two parathyroid hormone assays during life were normal).
== Images ==
File:IPLab2Calcification8.jpg|This gross photograph affords a closer view of the same aortic valve. Note the nodularity and thickening of this valve due to fibrosis and dystrophic calcification.
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== Virtual Microscopy ==
=== Lung: Metastatic Calcification ===
<peir-vm>IPLab2Calcification</peir-vm>
 
=== Normal Lung ===
<peir-vm>UAB-Histology-00107</peir-vm>
== Study Questions ==
* Hypercalcemia of malignancy</spoiler>
== Additional Resources ==
=== Reference ===
* [http://emedicine.medscape.com/article/240681-overview eMedicine Medical Library: Hypercalcemia]
* [http://www.merckmanuals.com/professional/gynecology_and_obstetrics/breast_disorders/breast_cancer.html Merck Manual: Breast Cancer]
* [http://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/electrolyte_disorders/hypercalcemia.html Merck Manual: Hypercalcemia]
* [http://www.cancer.gov/cancertopics/types/breast National Cancer Institute: Breast Cancer]
 
=== Journal Articles ===
* Ullmer E, Borer H, Sandoz P, Mayr M, Dalquen P, Solèr M. [http://www.ncbi.nlm.nih.gov/pubmed/11591586 Diffuse pulmonary nodular infiltrates in a renal transplant recipient. Metastatic pulmonary calcification]. ''Chest'' 2001 Oct;120(4):1394-8.
 
=== Images ===
* [{{SERVER}}/library/index.php?/tags/1450-metastatic_calcification PEIR Digital Library: Metastatic Calcification Images]
* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html WebPath: Pulmonary Pathology]
{{IPLab 2}}
[[Category: IPLab:Lab 2]]