HISTOLOGY: MICROBIOLOGY: TONGUE: Oral manifestations of HIV infection and AIDS. Biopsy of hairy leukoplakia lesion.; Note large vacuolated cells, with pyknotic nuclei (koilocytes) and some cells with halo around nuclei. Contributed by Sol Silverman, Jr., D.D.S., University of California, San Francisco for the Centers for Disease Control. L-235: 04