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00210977

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KARYOTYPE: LYMPH NODE: Evolved B cell NonHodgkins lymphoma, NHL; t(8;14) and t(14;18), appears in 75% of follicular NHL, juxtaposing the bcl-2 (band 18q21) proto-oncogene with Ig (band 14q32) heavy chain gene (resulting in deregulation of bcl-2 (inhibits apoptosis). Besa/Peter C. Nowell, M.D. Karyotype

Author
Peter Anderson
Keywords
karyotype, lymph node
Visits
2389

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