PEIR Digital Library

Welcome to the Pathology Education Informational Resource (PEIR) Digital Library, a multidisciplinary public access image database for use in medical education.

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DIAGRAM: JOINT: Pathogenesis of Rheumatoid Arthritis, Graphic View-EARLY STAGE; Arrow on Lymphocyte -- Soft tissue swelling and hyperemia are observed in the earliest stage, indicative of synovitis and an increase in the volume of synovial fluid. Neutrophils and lymphocytes begin to accumulate in the synovial fluid.