DIAGRAM: GASTROINTESTINAL: GI: ARTERY: Pathogenesis of Atherosclerosis - 10 of 13; A=Lipoprotein, B=Thrombus, C=Smooth Muscle Cell, D=Fibrous Plaque, E=Foam Cell -- At this point, fatty streaks may become directly converted to fibrous plaques through release of growth factors from macrophages, endothelial cells, or both.