RADIOLOGY: GASTROINTESTINAL: GI: Case# 34077: ALPHA 1 ANTITRYPSIN DEFICIENCY CIRRHOSIS COLITIS VASCULITIS. Patient is a 42 year old male with Alpha I antitrypsin deficiency. here is cirrhosis and moderate splenomegaly as well as numerous varices around the splenic hilum and GE junction. There is trace fluid in the pelvis and some fluid adjacent to the colon. No focal liver lesions identified, however. However, the contrast bolus was suboptimal due to a leak in the IV. No intra- or extrahepatic biliary dilatation. There is moderate gallbladder wall edema. There is marked colonic mucosal edema most notably in the hepatic flexure but moderate in the splenic flexure and descending colon as well. Moderate inflammatory changes around the colon in the thickened areas. No evidence of free intraperitoneal gas or obstruction or extravasation of contrast material.