RADIOLOGY: GASTROINTESTINAL: GI: Case# 32844: RECTAL CARCINOMA. This is a 49 year old female follow-up case of colon cancer who is status post two colon resections in the past. She is also status post hysterectomy eight years ago. The patient now presents with a history of rectal bleeding. CT scan is being done to evaluate recurrent disease. An irregular annular mass is present in the rectosigmoid colon There is no evidence of invasion of the surrounding structures. No pelvic or intra-abdominal lymph node enlargement is present. Visualized portions of liver and spleen are unremarkable in appearance without any focal lesion. Both adrenals, kidneys as well as the rest of the intra-abdominal bowel loops are unremarkable. There is no evidence of intestinal obstruction or free air evident. Colorectal adenocarcinoma is one of the most common neoplasms encountered in the affluent countries of the Western world. The disease exhibits a peak age incidence in the sixth and seventh decades. It is associated with increased serum concentration of carcinoembryonic antigen (CEA). Predisposing factors for colorectal cancer include adenomatous polyps, inherited multiple polyposis syndromes, long-standing ulcerative colitis, close relatives with colon cancer, and a low fiber, high animal fat diet. Colorectal cancer varies in gross presentation according to the region of the colon involved. Carcinoma of the rectosigmoid colon usually presents in an annular manner, often producing early bowel obstruction. Carcinoma of the right colon, however, usually does not obstruct early and frequently presents with iron deficiency anemia secondary to chronic blood loss. Colon cancer spreads by direct extension due to penetration of the colon wall, lymphatic drainage to regional nodes, through the portal system to the liver, and intraperitoneal seeding. Although barium enemas and colonoscopy are the primary methods used to initially diagnose colorectal cancer, CT is an excellent procedure for the detection of recurrence. CT findings of colon cancer include focal lobulated soft tissue mass in the colon, localized thickening of greater than 5 mm of the bowel wall, irregular lumen surface, extension of linear soft tissue densities or discrete mass into pericolic fat or adjacent organs, regional adenopathy, and liver metastases. Soft tissue masses visualized within the peritoneal cavity may signify metastases or recurrence of the cancer. Calcification in the primary tumor can be seen with mucinous adenocarcinoma.