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• 06:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF11.jpg (This higher-power photomicrograph shows more clearly the eosinophilic debris (arrows) in the intestinal crypts.)
• 06:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF10.jpg (This is a higher-power photomicrograph showing the eosinophilic debris in many of the intestinal crypts (arrows).)
• 06:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF9.jpg (A higher-power photomicrograph shows the bottom of the intestinal crypts and the other normal layers of the intestine. Even at this magnification, accumulations of eosinophilic debris can be seen in many of the intestinal crypts (arrows).)
• 06:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF8.jpg (This low-power photomicrograph of intestine shows the normal layers of the intestine, including the serosa (1), the muscularis (2), the submucosa (3), and the mucosal layer (4) with its deep mucosal crypts. There is yet another cystic space within the ...)
• 06:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF7.jpg (This is another high-power photomicrograph showing cystic spaces (1) within the acinar pancreas and a normal islet of Langerhans (2).)
• 06:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF6.jpg (This high-power photomicrograph shows more clearly these variably-sized cystic spaces within the acinar pancreas.)
• 06:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF5.jpg (This higher-power photomicrograph shows a cystic space (1) within an acinar lobule. Islets of Langerhans (2) are also visible.)
• 06:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF4.jpg (This higher-power photomicrograph of the pancreas shows interstitial tissue and the presence of small cystic spaces (1) within the acinar lobules. These spaces are filled with an eosinophilic proteinaceous material. The islets of Langerhans (2) are una...)
• 05:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF3.jpg (This low-power photomicrograph of pancreas shows increased interstitial connective tissue resulting in accentuation of the lobular pattern.)
• 05:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF2.jpg (This section of duodenum demonstrates dilation, loss of rugae, and areas of ulceration (arrows).)
• 05:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13CF1.jpg (This is a gross photograph of liver and pancreas from the autopsy. The pancreas is slightly smaller than normal and it has a mucous consistency.)
• 05:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT10.jpg (This high-power photomicrograph shows the differences in cell morphology between the blastema (1) and the fibroblast type cells (2).)
• 05:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT9.jpg (This high-power photomicrograph demonstrates tubule formation within the blastema. Note the numerous mitotic figures (arrows).)
• 05:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT8.jpg (This is a high-power photomicrograph of "tubule" formation within the blastema (arrows).)
• 05:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT7.jpg (This is another medium-power photomicrograph of the tumor. It demonstrates again the two cell types making up this neoplasm. The glands or "tubules" within the blastema are better developed in this section (arrows).)
• 05:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT6.jpg (This medium-power photomicrograph of tumor shows again the two cell types making up this neoplasm. There are regions within the blastema where the cells form glands or "tubules" (arrows).)
• 05:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT5.jpg (This low-power photomicrograph of tumor shows the two cell types making up this neoplasm. The basophilic cellular component termed "blastema" (1) can be distinguished from less cellular eosinophilic areas with fibroblast-like cells (2).)
• 05:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT4.jpg (This lowest-power view shows the tumor itself; no tissue is present that can be readily identified as normal kidney. There does appear to be a capsule surrounding the tumor. Eosinophilic bands are seen surrounding basophilic islands of cells. These cor...)
• 05:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT3.jpg (This is a gross photograph of lung from this case demonstrating the metastatic tumor nodule (arrow).)
• 05:54, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT2.jpg (This is a closer view of the kidney with Wilms' tumor (arrows).)
• 05:54, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13WT1.jpg (This is a gross photograph of a bladder (1) to which are attached a normal kidney (2) and a kidney with Wilms' tumor (3). A large mass extends from the superior pole of the affected kidney. The renal capsule can be seen extending around this tumor.)
• 05:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline9.jpg (This higher-power photomicrograph shows more clearly the hyaline membranes (arrows) and the congestion in the interstitium.)
• 05:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline8.jpg (This medium-power photomicrograph shows the pink acellular homogeneous material lining the alveoli which comprises the hyaline membranes (arrows). The interstitium shows congestion, as in previous sections.)
• 05:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline7.jpg (This high-power photomicrograph shows an airway with adjacent lung tissue. Some alveoli have hyaline membranes (arrows). There is severe congestion of the interstitium throughout this section.)
• 05:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline6.jpg (This is a medium-power photomicrograph showing a large bronchus with cartilage. Interstitial congestion with numerous red cells is apparent. Even at this magnification hyaline membranes (arrows) can be seen lining the alveoli.)
• 05:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline5.jpg (This low-power photomicrograph of lung demonstrates hypercellular pulmonary interstitium and small air spaces (as compared to adult lungs).)
• 05:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline4.jpg (This high-power photomicrograph of liver shows more clearly the immature blood cell precursors (arrows) which represent extramedullary hematopoiesis of the liver. The liver is a normal site of fetal hematopoiesis and, for this stage of gestation, extra...)
• 05:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline3.jpg (This is a low-power photomicrograph of liver which contains dark blue-stained cells in the hepatic sinusoids. These are immature blood cell precursors and this represents extramedullary hematopoiesis of the liver.)
• 05:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline2.jpg (This is a low-power photomicrograph of a triangular-shaped section of lung (1) and an oblong section of liver (2). The lack of open air spaces in this neonatal lung indicates its immaturity.)
• 05:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Hyaline1.jpg (This is a gross photograph of lung demonstrating hyaline membrane disease and atelectasis.)
• 05:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13BiliaryAtresia5.jpg (This is a medium-power photomicrograph of liver section stained with a trichrome stain to demonstrate the portal fibrosis. The fibrous connective tissue (collagen) stains blue.)
• 05:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13BiliaryAtresia4.jpg (This is a high-power photomicrograph of fibrotic portal region with several bile ducts that contain inspissated bile (arrows). Adjacent hepatocytes also contain bile pigments.)
• 05:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13BiliaryAtresia3.jpg (This high-power photomicrograph of fibrotic portal region demonstrates proliferation of the bile ducts (arrows).)
• 05:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13BiliaryAtresia2.jpg (This medium-power photomicrograph of liver shows an area of portal fibrosis and bile duct proliferation (arrows). Adjacent to this fibrotic portal region, hepatocytes are seen separated by dilated sinusoids. Throughout this section are found accumulati...)
• 05:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13BiliaryAtresia1.jpg (This is a low power photomicrograph of a section of liver. Even at this low magnification, areas of fibrosis can be appreciated.)
• 05:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Myelomeningocele7.jpg (This high-power photomicrograph of the spinal cord within the vertebral column shows the hemorrhage (arrows) in this region.)
• 05:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Myelomeningocele6.jpg (This is a high-power photomicrograph of the spinal cord (arrow) immediately beneath the area of hemorrhage.)
• 05:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Myelomeningocele5.jpg (This is a higher-power photomicrograph of one of the vertebral bodies from this case. The defect (arrows) in the vertebral body is seen more clearly. The spinal cord is disrupted and there are areas of hemorrhage in this region.)
• 05:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Myelomeningocele4.jpg (This is a low-power photomicrograph of one of the vertebral bodies from this case. In this section there are defects (arrows) in the vertebral body but the skin can be seen over the open vertebral canal.)
• 05:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Myelomeningocele3.jpg (This is a closer view of the previous gross photograph showing a normal lumbar vertebra from this case on the left. Once again, note the defect (arrow) in the vertebral body on the right due to failure of the vertebral column to close properly.)
• 05:44, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Myelomeningocele2.jpg (This gross photograph shows consecutive lumbar vertebra from this case. Note the defect (arrows) in the two vertebral bodies on the right. This defect was caused by failure of the vertebral column to properly close.)
• 05:44, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab13Myelomeningocele1.jpg (This is a gross photograph of the fetus at autopsy. Note the defect in the lower lumbar region of the spinal column (arrow). The myelomeningocele can be seen protruding from this defect.)
• 05:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12COPD5.jpg (This gross photograph of the heart taken at autopsy demonstrates right ventricular hypertrophy and dilatation (arrows).)
• 05:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12COPD4.jpg (This higher-power photomicrograph of the lung shows more clearly the enlarged air spaces indicative of emphysematous change.)
• 05:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12COPD3.jpg (This low-power photomicrograph of the lung demonstrates the enlarged air spaces indicative of emphysematous change.)
• 05:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12COPD2.jpg (This is a higher-power view of the lung showing the emphysematous change.)
• 05:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12COPD1.jpg (This gross photograph of lung taken at autopsy demonstrates the degree of emphysematous change (arrows). Also note that the rest of the lung is consolidated, indicating a pneumonia.)
• 05:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns13.jpg
• 05:39, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns12.jpg (This photomicrograph of the trachea shows sloughing of the tracheal epithelium and the black carbonaceous material contained therein (1). This degree of tracheal epithelial damage is indicative of severe inhalation injury. The tracheal cartilage rings ...)
• 05:39, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns11.jpg (This closer view of the lung shows the black carbonaceous material in the trachea as well as in the main stem bronchi.)
• 05:39, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns10.jpg (This photograph of the lung again shows the black carbonaceous material in the trachea as well as in the main stem bronchi. The lungs are mildly congested and hyperemic. The patient lived for less than 8 hours after the burn injury so there was not eno...)
• 05:39, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns9.jpg (This photograph demonstrates the black carbonaceous material in the trachea.)
• 05:38, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns8.jpg (This medium-power photomicrograph of the burned skin shows the mild damage to the superficial layers of the epidermis.)
• 05:38, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns7.jpg (This photomicrograph of the burned skin depicts an area of first degree burn. Note that there are no blisters and no damage to the dermis. There is mild damage to the superficial epidermis and some hyperemia (arrow).)
• 05:38, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns6.jpg (This high-power photomicrograph of the burned skin shows the blister and the thrombosed vessels in the dermis.)
• 05:38, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns5.jpg (This medium-power photomicrograph of the burned skin demonstrates blister formation. The vessels in the dermis are congested (arrows).)
• 05:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns4.jpg (This high-power photomicrograph shows the denuded surface of the skin with thrombosed blood vessels (arrows) and necrosis of the dermis.)
• 05:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns3.jpg (This photomicrograph of the burned skin depicts an area of third degree burn. There is some residual epidermis (arrow) but in the majority of this section the epidermis is gone. Also note the severe subcutaneous edema.)
• 05:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns2.jpg (This closer view shows the burned skin peeling off to expose the underlying tissue. The various depths of the burn can be appreciated by the color and character of the underlying tissue.)
• 05:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Burns1.jpg (This photograph taken at autopsy demonstrates the severity of the surface burns on this patient.)
• 05:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma11.jpg (Scanning electron micrograph of asbestos bodies. Note the rough surface and the beaded appearance caused by the material adhering to the surface of the asbestos fiber.)
• 05:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma10.jpg (Another high-power photomicrograph of the brown asbestos bodies showing the characteristic beaded appearance (arrows). Tumor cells are evident adjacent to the asbestos bodies.)
• 05:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma9.jpg (This is a high-power photomicrograph of the brown asbestos bodies showing the characteristic beaded appearance (arrows).)
• 05:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma8.jpg (This high-power photomicrograph shows brown asbestos bodies (1), accumulations of anthracotic pigment (2), and tumor cells (3) all adjacent to a blood vessel (4).)
• 05:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma7.jpg (In this higher-power photomicrograph there is a blood vessel (1) and adjacent lymphatics that contain tumor cells (2). There are also accumulations of brown material adjacent to these vessels.)
• 05:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma6.jpg (In this higher-power photomicrograph the clusters of tumor cells (arrows) can be appreciated.)
• 05:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma5.jpg (This higher-power photomicrograph of left lung shows areas of consolidation and fibrosis (arrows). Also note that in many of these areas there are clusters of blue cells.)
• 05:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma4.jpg (This is a low-power photomicrograph of a section of the left lung. At this magnification you can see areas of consolidation (arrows), especially around blood vessels.)
• 05:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma3.jpg (This is a gross photograph of the thoracic surface of the diaphragm demonstrating the distinctive fibrocalcific plaque (arrows) produced by mesothelioma and multiple smaller plaques over the pleural surface of the diaphragm.)
• 05:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma2.jpg (This is a gross photograph of cut sections of the lungs. The right lung is congested. The left lung is shrunken and filled with tumor. There is a thick layer of tumor along the inferior portion of the lung (arrow).)
• 05:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Mesothelioma1.jpg (This is a gross photograph of the lungs removed at autopsy. There is thickening of the pleural surface due to the tumor (arrows). The apical portion of the left lobe of the lung was ripped while trying to sever the adhesions between the lung and the ch...)
• 05:30, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges8.jpg (This high-power photomicrograph of the wall of the ileum shows more examples of pleomorphic cells caused by radiation injury (arrows).)
• 05:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges7.jpg (This high-power photomicrograph of the wall of the ileum shows more examples of pleomorphic cells (arrows) due to radiation injury.)
• 05:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges5.jpg (This is a high-power photomicrograph of the wall of the ileum showing a blood vessel that has suffered radiation-induced damage and is completely occluded (arrows).)
• 05:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges6.jpg (This is a high-power photomicrograph of the wall of the ileum showing a blood vessel that has suffered radiation-induced damage and is completely occluded (arrows).)
• 05:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges4.jpg (This is a high-power photomicrograph showing the atrophied epithelium in the area of radiation injury (1). Note the dense fibrous connective tissue within the wall of the ileum and the congested blood vessels (2).)
• 05:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges3.jpg (This is a higher-power photomicrograph showing the atrophied epithelium in the area of radiation injury. There are some epithelial cells deep within the mucosa (1). Note the dense fibrous connective tissue (2) within the wall of the ileum.)
• 05:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges2.jpg (This is a higher-power photomicrograph of the surgical specimen of the ileum showing the transition from the normal epithelium (1) to the atrophied epithelium (2) in the area of radiation injury.)
• 05:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationChanges1.jpg (This is a low-power photomicrograph of the surgical specimen of the ileum. The normal ileum is to the left (1). The area of stricture consists of dense fibrous connective tissue (2) and there is loss or marked atrophy of the epithelium (3).)
• 05:25, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis13.jpg (This is a high-power photomicrograph of a recanalized blood vessel in the lung. Notice the anthracotic pigment adjacent to the vessel (arrows).)
• 05:25, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis12.jpg (This high-power photomicrograph shows intimal changes (arrows) in this blood vessel in the lung.)
• 05:25, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis11.jpg (This medium-power photomicrograph shows fibrosis and severe intimal changes in blood vessels (arrows).)
• 05:25, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis10.jpg (This is another high-power photomicrograph of an area of tissue with diffuse fibrosis and thickening of the alveolar septa. There are also accumulations of anthracotic pigment in this area (arrows).)
• 05:25, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis9.jpg (This is a photomicrograph of an area of tissue exhibiting diffuse fibrosis and thickening of the alveolar septa.)
• 05:24, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis8.jpg (This is a photomicrograph of a trichrome-stained section of lung demonstrating the extensive fibrosis throughout this section (green-blue stained material is fibrous connective tissue).)
• 05:24, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis7.jpg (This high-power photomicrograph of lung section shows the thickening of the alveolar septum (arrows) by fibrous connective tissue.)
• 05:24, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis6.jpg (This is another high-power photomicrograph of lung section showing the thickening of the alveolar septa (arrows) and accumulations of black anthracotic pigment.)
• 05:24, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis5.jpg (This is a higher-power photomicrograph of lung section. Note the thickening of the alveolar septa (1) and accumulations of anthracotic pigment (2).)
• 05:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis4.jpg (This is a low-power photomicrograph of lung section. Note the thickening of the alveolar septa (arrows).)
• 05:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis3.jpg (This is a gross photograph showing a closer view of a cut section of lung. An area of fibrosis (arrow) is evident in this photograph.)
• 05:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis2.jpg (This is a gross photograph of cut sections of lung. There are several areas of fibrosis (arrows) within the lung parenchyma.)
• 05:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12RadiationFibrosis1.jpg (This is a gross photograph of lung demonstrating areas of fibrosis on the pleural surface (arrow).)
• 05:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen8.jpg (This is a higher-power photomicrograph of the skin from this patient showing a blister and the thrombosed small vessels (arrows) in the dermis.)
• 05:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen7.jpg (This low-power photomicrograph of the skin from this patient shows a blister and numerous thrombosed vessels (arrows) in the dermis.)
• 05:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen6.jpg (Photograph taken at autopsy demonstrating the severe necrosis of the skin of foot.)
• 05:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen5.jpg (This is a high-power photomicrograph of the edge of the necrosis. Again, note the coagulation necrosis and hemorrhage in this area. The viable hepatocytes at the edge of this necrosis are vacuolated (arrows).)
• 05:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen4.jpg (This is a medium-power photomicrograph of the areas of hemorrhagic necrosis. Note the coagulation necrosis and hemorrhage in this area. Viable hepatocytes can be seen along the edge of this lesion.)
• 05:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen3.jpg (This is another example of the areas of hemorrhagic necrosis (arrows).)
• 05:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen2.jpg (In this photomicrograph of the liver from this patient there are areas of hemorrhagic necrosis (arrows).)
• 05:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Acetaminophen1.jpg (This gross photograph of the liver from this patient demonstrates the pale areas of necrosis (arrows).)
• 05:17, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic14.jpg (This is another photograph of the cerebellum from this patient demonstrating the marked thinning of the anterior portion of the cerebellum (arrows). This pattern of cerebellar damage is consistent with Wernicke's encephalopathy.)
• 05:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic13.jpg (This photograph of the cerebellum from this patient demonstrates the marked thinning of the anterior portion of the cerebellum (arrows).)
• 05:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic12.jpg (This photomicrograph shows the dilated vessel just under the epithelium of the esophagus.)
• 05:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic11.jpg (This photograph taken from still another patient at autopsy demonstrates the esophageal varices in the distal esophagus (arrows). The esophagus was clamped before removing the esophagus from the body in order to trap the blood in these distended varice...)
• 05:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic10.jpg (This is a photograph taken from another patient at autopsy to demonstrate numerous esophageal varices in the distal esophagus (arrows). None of these varices have ruptured.)
• 05:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic9.jpg (In this closer view of the distal esophagus the ruptured varix is indicated by the probe. Other varices and areas of submucosal hemorrhage can also be appreciated.)
• 05:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic8.jpg (This photograph taken at autopsy shows the distal portion of the esophagus and the stomach. The esophageal varices are visible just under the mucosa of the esophagus (arrows). Some of the blood from the ruptured varix can still be seen in the stomach.)
• 05:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic7.jpg (This photograph was taken during the EGD while the patient was alive. Note the red hyperemic areas (1) and the area of hemorrhage (2).)
• 05:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic5.jpg (In this high-power photomicrograph of trichrome-stained liver, the bands of fibrous tissue surround the hepatocyte nodules. There is some degeneration and dropout of hepatocytes in this nodule. Also note the increased numbers of bile ducts in the triad...)
• 05:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic6.jpg (In this high-power photomicrograph of trichrome-stained liver, the bands of fibrous tissue surround the hepatocyte nodules. There is some degeneration and dropout of hepatocytes in this nodule. Also note the increased numbers of bile ducts in the triad...)
• 05:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic4.jpg (In this is medium-power photomicrograph of trichrome stained liver the bands of fibrous tissue are seen to form "bridges" between triad areas (arrows); this is called "bridging fibrosis." Also note the fibrous tissue (arrows) and how the hepatocytes ar...)
• 05:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic3.jpg (This is a low-power photomicrograph of this liver stained with a trichrome stain to highlight the fibrous tissue (arrows). Also note the nodular pattern.)
• 05:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic2.jpg (This is a closer view of the liver from this patient. Again note the nodular pattern and the areas of greenish discoloration. These green nodules are actually the viable hepatocytes that are stained green because of bile stasis. The pale areas are the ...)
• 05:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab12Alcoholic1.jpg (This is a gross photograph of the liver from this patient. Note the nodular pattern and the areas of greenish discoloration as well as pale tan areas.)
• 05:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Chagas6.jpg (This is a higher-power photomicrograph of an H & E stained heart biopsy from this patient. Note the T. cruzi amastigotes (arrows) within this longitudinal section of a myocyte.)
• 05:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Chagas5.jpg (This is a higher-power photomicrograph of an H & E stained heart biopsy from this patient. At this magnification the organisms within a myocyte (arrows) and the adjacent inflammatory response are more clearly seen. The individual organisms within the m...)
• 05:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Chagas4.jpg (This is a higher-power photomicrograph of an H & E stained heart biopsy from this patient. Again, note the organisms within a myocyte (arrow) and the inflammatory response.)
• 05:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Chagas3.jpg (This is a low-power photomicrograph of an H & E stained section from the heart biopsy of this patient. Note the organisms within a myocyte (arrow) and the adjacent inflammatory response.)
• 05:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Chagas2.jpg (This peripheral blood smear from the patient shows a higher power view of a Trypanosoma cruzi trypomastigote. Note the prominent kinetoplast (arrow).)
• 05:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Chagas1.jpg (This peripheral blood smear from the patient shows two trypomastigotes of Trypanosoma cruzi.)
• 05:05, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Schistosomiasis3.jpg (This is a photomicrograph of the liver from another patient with Schistosoma mansoni. These eggs have elicited a robust inflammatory response, including a multinucleated giant cell. These lesions go on to heal by fibrosis resulting in cirrhosis and the...)
• 05:05, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Schistosomiasis2.jpg (This is high-power photomicrograph of the patient's fecal specimen containing another Schistosoma mansoni egg.)
• 05:05, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Schistosomiasis1.jpg (This is a high-power photomicrograph of the patient's fecal specimen containing the characteristic egg of Schistosoma mansoni. Note the spine on the egg (arrow).)
• 05:04, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Cysticercosis4.jpg (This is a photograph of the body of an adult tapeworm. Note the body segments.)
• 05:04, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Cysticercosis3.jpg (This photograph of an autopsy specimen from another patient shows an adult tapeworm in the intestine. Note that the worm attaches to the luminal surface of the intestine via the scolex.)
• 05:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Cysticercosis2.jpg (This is a photograph of the cyst that was surgically removed. The cyst is filled with a clear fluid and contains a scolex.)
• 05:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Cysticercosis1.jpg (This is a head CT showing the two cysts (arrows).)
• 05:02, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Ascariasis7.jpg (This high-power photomicrograph of the fecal specimen from this patient shows a Giardia lamblia cyst (arrow).)
• 05:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Ascariasis6.jpg (This high-power photomicrograph of the fecal specimen from this patient shows a Giardia lamblia trophozoite. Note the two nuclei and the tapered end (that goes out of the plane of focus) containing flagella (arrow).)
• 05:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Ascariasis5.jpg (This high-power photomicrograph of the fecal specimen from this same patient shows an Entamoeba histolytica cyst (arrow).)
• 05:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Ascariasis4.jpg (This is a higher-power photomicrograph of another ascarid egg.)
• 05:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Ascariasis3.jpg (This is a high-power photomicrograph of a fecal specimen from this patient showing an ascarid egg (arrow).)
• 05:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Ascariasis2.jpg (This is a photograph of an autopsy specimen from another case of ascariasis. The adult ascarid (arrow) can be seen in the section of small bowel from this patient.)
• 05:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Ascariasis1.jpg (This is a photograph of an adult ascarid like the ones removed from the small bowel of this patient.)
• 04:58, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Leishmaniasis6.jpg (This is a high-power photomicrograph of a touch prep made from the skin lesion at the time of biopsy. A single macrophage can be seen with intracytoplasmic leishmania organisms (arrows).)
• 04:58, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Leishmaniasis5.jpg (This is a high-power photomicrograph of an inflammatory cell containing cytoplasmic organisms (arrows).)
• 04:58, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Leishmaniasis4.jpg (This high-power photomicrograph of the biopsy specimen shows more clearly the heavily infiltrate of inflammatory cells. Note the small blue structures inside the inflammatory cells (arrows).)
• 04:58, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Leishmaniasis3.jpg (This is a higher-power photomicrograph of this biopsy. The ulcerated surface is seen on the top of the section. Again, note that the specimen is heavily infiltrated with inflammatory cells.)
• 04:58, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Leishmaniasis2.jpg (This is a low-power photomicrograph of the biopsy taken from this skin lesion. The ulcerated surface is at the top. Note that the specimen is heavily infiltrated with inflammatory cells.)
• 04:57, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Leishmaniasis1.jpg (In this photograph of the skin lesion seen in this patient, note the raised edges (arrows) and the ulcerated center.)
• 04:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Malaria7.jpg (In this peripheral smear from a different patient who was infected with P. vivax, the cytoplasm of the infected RBC has a stippled appearance (Schüffner's dots) (arrow). The RBC is also slightly enlarged.)
• 04:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Malaria6.jpg (This high photomicrograph was taken from another patient who died of malignant cerebral malaria caused by P. falciparum. In this photomicrograph, a small artery (arrow) can be seen that is full of parasitized RBCs. These RBCs tend to clog small blood v...)
• 04:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Malaria5.jpg (There is another example of a P. falciparum gametocyte (arrow) in this thin smear. There is a neutrophil in this field as well.)
• 04:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Malaria4.jpg (In this high power photomicrograph of a thin smear of blood from this patient there is one P. falciparum gametocyte (arrow). These gametocytes have a characteristic "banana" shape.)
• 04:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Malaria3.jpg (This is yet another high power photomicrograph of a thin smear of blood from this patient. There is one RBC that contains two ring stage trophozoites (arrow). This is characteristic of, but not diagnostic for, P. falciparum.)
• 04:54, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Malaria2.jpg (This is another high power photomicrograph of a thin smear of blood from this patient. There is a single eosinophil in this smear along with several RBCs containing ring stage trophozoites (arrows).)
• 04:54, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab11Malaria1.jpg (This is a high power photomicrograph of a thin smear of blood from this patient. Note that one of the RBCs has a ring stage trophozoite (arrow).)
• 04:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor8.jpg (This is another high-power photomicrograph of the thrombus stained to outline the Mucor organisms (arrows).)
• 04:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor7.jpg (This is an even higher-power photomicrograph of the thrombus stained to outline the Mucor organisms (arrows).)
• 04:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor6.jpg (This medium-power photomicrograph shows the thrombus stained to outline the Mucor organisms (arrows). Note again the ribbon-like morphology and the wide-angle branching.)
• 04:20, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor5.jpg (This is another high-power photomicrograph of the wall of the artery and the thrombus. Within the thrombus there are multiple variably-shaped clear areas that represent longitudinal sections and cross sections of the Mucor organisms (arrows).)
• 04:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor4.jpg (This is a higher-power photomicrograph of just the wall of the carotid artery. Note the ribbon-like clear structure with roughly parallel walls (non-septate hyphae) and right-angle branching (arrow). This is the Mucor organism.)
• 04:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor3.jpg (This is an even higher-power photomicrograph of the wall of the carotid artery (1) and the thrombus (2). Within the wall of the artery and in the thrombus there are multiple variably shaped clear areas (3). At this magnification and with this stain, it...)
• 04:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor2.jpg (This is a higher-power photomicrograph of the wall of the carotid artery (1) and the thrombus (2).)
• 04:19, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Mucor1.jpg (This is a low-power photomicrograph of a section of carotid artery containing a mural thrombus.)
• 04:17, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto10.jpg (This is a very high-power photomicrograph showing Blastomyces organisms stained with PAS. Note the budding organism (arrow) and the underlying pyogranulomatous inflammatory reaction in the background.)
• 04:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto9.jpg (This high-power photomicrograph shows Blastomyces organisms stained with PAS. Note the budding organism (arrow). Blastomyces has a characteristic presentation of budding which aids in diagnosis of the fungus.)
• 04:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto8.jpg (This is a high-power photomicrograph showing an alveolus filled with Blastomyces organisms. This section is stained with Periodic Acid-Schiff (PAS) to stain the Blastomyces organisms.)
• 04:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto7.jpg (This high-power photomicrograph shows an alveolus filled with numerous round bodies up to 25 mm in diameter. Some of these double-contour bodies (1) have a dense center and a clear halo. These are the Blastomyces organisms. The typical B. dermatitides ...)
• 04:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto6.jpg (This high-power photomicrograph shows what appear to be inflammatory cells filling the alveoli. At this magnification, numerous round bodies (arrows) that look like inflammatory cell nuclei can be seen. However, on closer examination, some of these rou...)
• 04:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto5.jpg (This is a higher-power photomicrograph of lung section with pleura. The pleura (arrows) is thickened and contains inflammatory cells and fibrin. The alveoli are filled with inflammatory cells. Some of the alveolar septa are congested with red blood cells.)
• 04:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto4.jpg (This is a high-power photomicrograph of lung section with pleura. The pleura (1) is thickened and contains inflammatory cells and fibrin. The areas of consolidation (2) are dense and filled with inflammatory cells.)
• 04:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto3.jpg (This is a low-power photomicrograph of lung showing many areas of consolidation (arrows).)
• 04:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto2.jpg (This higher-power view of the lung shows more clearly the areas of necrosis (1) and consolidation (2). Satellite lesions are also present (3).)
• 04:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Blasto1.jpg (This gross photograph of the lungs shows areas of necrosis and consolidation.)
• 04:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto12.jpg (This is a touch prep of fresh lung tissue that was allowed to air dry and then stained to show the mucopolysaccharide capsule around the cryptococcal organisms (arrows).)
• 04:12, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto11.jpg (This is a higher-power photomicrograph of lung section stained with Alcian blue. The mucopolysaccharide capsule shrinks during processing with this stain, thereby producing a shrunken central appearance with the formation of spikes around each organism.)
• 04:12, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto10.jpg (This is a low-power photomicrograph of lung section stained with Alcian blue, which stains the acidic glycosaminoglycans making up the coat of the cryptococcal organism.)
• 04:12, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto9.jpg (This higher-power photomicrograph of a cryptococcal organism shows more clearly the nucleus surrounded by the large extracellular capsule (arrows).)
• 04:12, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto8.jpg (Cryptococcal organisms can also be seen in this high-power photomicrograph of the cryptococcal lesion. Some of the organisms have a well-defined halo (arrows) due to the mucopolysaccharide coat which surrounds them.)
• 04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto7.jpg (This is another high-power photomicrograph of the cryptococcal lesion. In this section, numerous cryptococcal organisms (5-10 mm in diameter) can be seen (arrows). Note that there is very little inflammatory reaction.)
• 04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto6.jpg (This is a high-power photomicrograph of the cryptococcal lesion. Some of the organisms have been expelled during processing, but some cryptococcal organisms can be seen (arrows).)
• 04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto5.jpg (This is a higher-power photomicrograph of the cryptococcal lesion. The air spaces are filled with organisms (arrows).)
• 04:11, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto4.jpg (This is a low-power photomicrograph of the lung from the lesion seen on x-ray. Note that there is little, if any, inflammatory reaction.)
• 04:10, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto3.jpg (This is another section of this lung showing consolidation (arrows).)
• 04:10, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto2.jpg (This is a gross photomicrograph of this lung taken at autopsy. Note the areas of emphysema (1) and consolidation (2).)
• 04:10, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Crypto1.jpg (This is the chest x-ray showing the mass (arrow) in the right lower lobe.)
• 04:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo7.jpg (This photomicrograph was taken under oil immersion to show the silver-stained Histoplasma organisms. Some of the organisms appear to be budding (arrows).)
• 04:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo6.jpg (This is a high-power photomicrograph of the same section of tissue as the previous slide. This section, however, has been stained with methenamine silver which causes the Histoplasma organisms to stain black (arrows).)
• 04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo5.jpg (This high-power photomicrograph shows small (2-5 mm) dark-staining organisms in the cytoplasm of many of these cells (arrows).)
• 04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo4.jpg (This high-power photomicrograph was taken at the edge of the area of necrosis. There is a mild inflammatory infiltrate along the edge of the necrosis.)
• 04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo3.jpg (This is an even higher-power photomicrograph of an area of necrosis (arrows). There is loss of cellular detail within this area. There are inflammatory cells present; however, it is difficult to differentiate the inflammatory cells from the native lymp...)
• 04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo2.jpg (This higher-power photomicrograph of the previous adrenal gland shows more clearly the irregularly-shaped area of necrosis (arrows).)
• 04:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Histo1.jpg (This low-power photomicrograph shows a section of adrenal gland with several irregularly-outlined areas of necrosis.)
• 04:04, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis8.jpg (This is a higher-power photomicrograph of a Candida colony in the kidney. Note the pseudohyphae of the Candida organisms.)
• 04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis7.jpg (This is a low-power photomicrograph of the kidney from this same case. Note the Candida colonies (arrows). The pseudohyphae are evident around the periphery of these colonies even at this low magnification.)
• 04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis6.jpg (This high-power photomicrograph shows the yeasts (1) and pseudohyphae (2).)
• 04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis5.jpg (This higher-power photomicrograph shows the yeasts and pseudohyphae in this focus of Candida organisms.)
• 04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis4.jpg (This is a low-power photomicrograph of one of the Candida colonies from this lymph node. The chains of yeast which are termed "pseudohyphae" are apparent at this magnification.)
• 04:03, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis3.jpg (This is a low-power photomicrograph of lymph node with three prominent areas of Candida colonies (arrows). Even at this low magnification, the purple-staining yeast and pseudohyphae can be easily seen. This section was stained with Periodic Acid-Schiff...)
• 04:02, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis2.jpg (This photograph of the cut surface of these kidneys shows that these multifocal punctate lesions are primarily in the cortex (arrows).)
• 04:02, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab10Candidiasis1.jpg (This autopsy photograph of the kidneys demonstrates the multifocal punctate lesions visible on the serosal surface (arrows). Don't confuse these small yellow punctate lesions with the fat that is adherent to the renal capsule.)
• 03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis5.jpg (This is a high-power photomicrograph of an actinomycotic colony. The filamentous nature (arrows) of the actinomyces organisms is more easily appreciated at this power.)
• 03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis4.jpg (This is an even higher-power photomicrograph of actinomycotic colonies in the abscess. The filamentous nature (arrows) of the actinomyces organisms in these colonies can be appreciated.)
• 03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis3.jpg (This is a higher-power photomicrograph of actinomycotic colonies in the abscess.)
• 03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis2.jpg (This is a higher-power photomicrograph of an abscess demonstrating a pocket of purulent exudate that contains numerous actinomycotic colonies (arrows).)
• 03:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Actinomycosis1.jpg (This is a low-power photomicrograph of the retroperitoneal abscess. At this magnification, multiple dark-staining foci can be appreciated. These foci are Actinomyces colonies (arrows). These colonies are known as "sulfur granules" because in gross spec...)
• 03:57, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium7.jpg (This is a high-power photomicrograph of a tissue section stained with a tissue Gram's stain (Brown & Brenn). The Gram-positive bacilli can be seen throughout this tissue section.)
• 03:57, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium6.jpg (This higher-power photomicrograph of the previous image provides a clearer view of gas bubbles in the tissue, the necrotic hypereosinophilic muscle cell (1), and the mild inflammatory reaction (2). At this magnification, the bacteria located throughout...)
• 03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium5.jpg (This high-power photomicrograph shows the gas accumulation present in the tissue, a necrotic muscle cell (1), and a mild inflammatory response (2). There is also a thrombosed blood vessel (3). The blue-staining rods (bacterial organisms) can barely be ...)
• 03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium4.jpg (This is a high-power photomicrograph of skeletal muscle. The muscle cells are hypereosinophilic and most do not contain nuclei, indicating that these cells are dead or dying. The round clear spaces (1) in this tissue correspond to gas accumulations pri...)
• 03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium3.jpg (This is a low-power photomicrograph of muscle fascicles containing large gas bubbles (arrows). Note that there is no inflammatory reaction in this section.)
• 03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium2.jpg (This gross photograph shows a close-up view of hemorrhagic blebs (arrows) on the skin. The blebs on the skin are accumulations of gas being discharged into the tissues from the Clostridium perfringens. This gas produces crepitance.)
• 03:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Clostridium1.jpg (This gross photograph of the lower extremity was taken at autopsy. Notice the swelling and the area of the primary infection (arrow).)
• 03:53, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF6.jpg (This high-power photomicrograph of myocardium shows the cellular detail of another Aschoff body. In this case there appears to be a multinucleated Aschoff giant cell (arrow).)
• 03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF5.jpg (This high-power photomicrograph of myocardium shows the cellular detail of an Aschoff body. Aschoff bodies are foci of fibrinoid necrosis surrounded by lymphocytes, macrophages, an occasional plasma cell, and plump “activated” histiocytes called An...)
• 03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF4.jpg (This is a higher-power photomicrograph of myocardium containing Aschoff bodies (arrows) within the interstitium.)
• 03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF3.jpg (This is a higher-power photomicrograph of myocardium showing cellular accumulations--Aschoff bodies (arrows)--within the interstitium of the myocardium. These are found especially around blood vessels.)
• 03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF2.jpg (This is a low-power photomicrograph of heart tissue. Little can be seen at this magnification, except that the tissue looks relatively normal.)
• 03:52, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9ARF1.jpg (This is a gross photograph of mitral valve demonstrating marked thickening and fibrosis of the valve leaflet. There are also numerous foci of fibrinoid necrosis within the cusps and friable vegetations (verrucae) along the lines of closure (arrows). Th...)
• 03:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria4.jpg (In this higher-power photomicrograph of the tissue from the previous image, the ulcerated tracheal mucosa and the diphtheritic membrane are more clearly seen. Although difficult to make out at this magnification, most of the cells in this inflammatory ...)
• 03:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria3.jpg (This is an even higher-power photomicrograph of the tracheal mucosa and the diphtheritic membrane. The mucosal surface of the trachea is ulcerated (total loss of epithelial cells) and the only remaining epithelial cells are found in the glands (arrows)...)
• 03:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria2.jpg (This is a higher-power photomicrograph of trachea with the diphtheritic membrane (1). Even though, the main part of the membrane has pulled away from the tracheal lining during histological processing, in this section part of the membrane is still loos...)
• 03:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9Diphtheria1.jpg (This is a low-power photomicrograph of the trachea with the diphtheritic membrane (1), which has pulled away from the tracheal lining during histological processing. Note the tracheal cartilage (2) present in this section.)
• 03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis8.jpg (This photomicrograph of brain tissue demonstrates diffuse edema.)
• 03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis7.jpg (This is a high-power photomicrograph of exudate from the leptomeninges which has been Gram-stained. Note the Gram-negative bacteria (arrows) throughout this section.)
• 03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis6.jpg (This is a high-power photomicrograph of a blood vessel from the previous image. The vessel is surrounded by neutrophils (arrows).)
• 03:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis5.jpg (This is a higher-power photomicrograph of inflammatory exudate in a sulcus. The majority of cells in this exudate are neutrophils. There is also abundant fibrin (arrows) and red blood cells are present in the congested vessels.)
• 03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis4.jpg (This higher-power photomicrograph of a sulcus shows the congested vessels and the inflammatory exudate in the leptomeninges.)
• 03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis3.jpg (This is a higher-power view of a congested blood vessel. Inflammatory exudate is present within the vessel and throughout the leptomeninges.)
• 03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis2.jpg (This is a low-power photomicrograph of brain section. Note the exudate (1) in the meninges and congestion of the vessels (2) in the leptomeninges.)
• 03:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9BacterialMeningitis1.jpg (This gross photograph of the autopsy specimen from this case demonstrates the purulent exudate (arrows) in the leptomeninges.)
• 03:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF8.jpg (This is a high-power photomicrograph of a thrombosed vessel in the dermis. Note that the endothelial cells are missing along part of the circumference of the vessel (arrows)--this is where the main part of the thrombus has attached. Also note the infla...)
• 03:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF7.jpg (This is a high-power photomicrograph of a dermal vessel (arrow) which is exhibiting vasculitis and thrombosis.)
• 03:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF6.jpg (This is a high-power photomicrograph of severe vasculitis in the dermis.)
• 03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF5.jpg (This is a photomicrograph of dermis with an area of more severe vasculitis (arrow).)
• 03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF4.jpg (This is a higher-power photomicrograph of a dermal vessel with mild vasculitis.)
• 03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF3.jpg (This is a photomicrograph of a small vessel in the dermis which is demonstrating mild vasculitis.)
• 03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF2.jpg (This is a higher-power photomicrograph demonstrating areas of hemorrhage immediately underneath the epidermis. Also note the cellularity and thrombosis of the small vessels in the dermis (arrow).)
• 03:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab9RMSF1.jpg (This is a low-power photomicrograph of the skin biopsy. Note areas of hemorrhage (arrow) in the dermis.)
• 02:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV10.jpg (This high-power photomicrograph of the previous section shows the HBcAg positive nuclei (arrows).)
• 02:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV9.jpg (This is a low-power photomicrograph of the same liver reacted with antibody specific for hepatitis B core antigen (HBcAg). The hepatocytes that contain HBcAg stain brown. Note that even at this low magnification, many brown-staining nuclei can be seen.)
• 02:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV8.jpg (This higher-power photomicrograph of the previous section shows more clearly the HBsAg positive cells (arrows). Upon staining with H&E, these same cells exhibit a "ground glass" appearance, which is due to the accumulation of HBsAg in the hepatocyte cy...)
• 02:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV7.jpg (This is a low-power photomicrograph of liver from the previous image which has been reacted with antibody specific for HBsAg. The hepatocytes that contain HBsAg stain brown.)
• 02:49, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV6.jpg (This is a photomicrograph of a liver section from another case of hepatitis B. In this H&E-stained section, the typical "ground glass" appearance of the hepatocytes can be appreciated (arrows).)
• 02:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV5.jpg (This high-power photomicrograph showing hepatocytes, the cytoplasm of which contain intracytoplasmic accumulations (arrows) of hepatitis B surface antigen.)
• 02:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV4.jpg (This is a high-power photomicrograph of liver with numerous hepatocytes containing accumulations of magenta-staining material in the cytoplasm (arrows).)
• 02:48, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV3.jpg (This is a higher-power photomicrograph of the periportal region exhibiting some inflammation and bile duct hyperplasia. There is also congestion and some loss of hepatocytes with disruption of the hepatic cords.)
• 02:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV2.jpg (This is a higher-power photomicrograph of liver from this case. Note the severe congestion (RBCs in sinusoids) and the presence of occasional hepatocytes with dark red/magenta-stained cytoplasm (arrows).)
• 02:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HBV1.jpg (This is a low-power photomicrograph of liver from this case. This section was stained with a modified aldehyde fuchsin and counterstained with hematoxylin and eosin. Modified aldehyde fuchsin colors cystine-rich proteins--such as HBsAg and elastic fibe...)
• 02:44, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio5.jpg (This is another high-power photomicrograph of the anterior horn with inflammatory cell infiltrate and total loss of neurons.)
• 02:44, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio4.jpg (This is a higher-power photomicrograph taken at the junction of the white and gray matter. Note the inflammatory cellular infiltrate and tissue breakdown. There is significant loss of neurons and myelin in this area.)
• 02:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio3.jpg (This is a high-power photomicrograph of the anterior horn of the spinal cord from this case. Note the absence of motor neurons and the diffuse gliosis.)
• 02:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio2.jpg (This is a higher-power photomicrograph of spinal cord from this case. Note the absence of motor neurons in the anterior horns and the gliosis (arrows).)
• 02:43, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Polio1.jpg (This is a low-power photomicrograph of a section of spinal cord from this case. Note that the anterior horns (arrows) are almost completely devoid of neurons.)
• 02:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies5.jpg (This is a high-power photomicrograph of a neuron surrounded by inflammatory cells (lymphocytes and microglia). This neuron has two intracytoplasmic eosinophilic inclusion bodies (arrows).)
• 02:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies4.jpg (This is a high-power photomicrograph of neurons containing variably-sized intracytoplasmic eosinophilic inclusion bodies (arrows).)
• 02:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies3.jpg (This is a higher-power photomicrograph of the shrunken neurons. One neuron appears to have an eosinophilic intracytoplasmic inclusion body (arrow).)
• 02:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies2.jpg (This is a medium-power photomicrograph of brain tissue exhibiting edema and evidence of shrunken, necrotic neurons (arrows).)
• 02:39, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8Rabies1.jpg (This is a low-power photomicrograph of the hippocampus (arrow) from this case.)
• 02:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis12.jpg (This is a photomicrograph of a brain section stained with an antibody against herpes simplex. Even at this magnification, it is easy to pick out cells that are positive for the virus (arrows).)
• 02:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis11.jpg (This is another high-power photomicrograph of a cell containing an intranuclear inclusion body (arrow).)
• 02:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis10.jpg (This is another high-power photomicrograph of a cell containing an intranuclear inclusion body (arrow). Note that the nuclear chromatin has been pushed to the outer edges of the nucleus.)
• 02:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis9.jpg (This is a high-power photomicrograph demonstrating cells containing intranuclear inclusion bodies (arrows).)
• 02:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis8.jpg (This is a high-power photomicrograph showing several necrotic cells (arrows).)
• 02:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis7.jpg (This is a high-power photomicrograph demonstrating clear areas, which indicate edema, and numerous shrunken red necrotic cells (1). At this power, it can be seen that eosinophilic intranuclear inclusion bodies have displaced chromatin to the periphery ...)
• 02:35, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis6.jpg (This is another high-power photomicrograph showing a blood vessel with perivascular hemorrhage and mild perivascular lymphocytic cuffing (arrow). In addition, there are numerous red shrunken neurons and glia with pyknotic nuclei throughout this section.)
• 02:35, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis5.jpg (This is a high-power photomicrograph of the previous section. At this power it is easier to see the blood vessel with the perivascular hemorrhage and mild perivascular lymphocytic cuffing (1). In addition, the areas of edema and loss of neurophil (2) c...)
• 02:35, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis4.jpg (This is a medium-power photomicrograph showing a blood vessel with perivascular hemorrhage (1), areas with loss of brain parenchyma, and edema (2). Even at this power, it can be seen that many of the cells are shrunken and dark red, suggesting that the...)
• 02:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis3.jpg (This is a low-power photomicrograph showing a section of brain with numerous perivascular hemorrhages (arrows) and some areas that appear hypercellular.)
• 02:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis2.jpg (This is a closer view of the previous section of brain showing multiple small, punctate hemorrhages throughout the brain parenchyma (arrows).)
• 02:34, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVEncephalitis1.jpg (This is a gross photograph of a section of brain showing multiple small, punctate hemorrhages throughout the brain parenchyma (arrows).)
• 02:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis5.jpg (This is a high-power photomicrograph of epithelium near the edge of the ulcer. The cells that have been invaded by the herpes virus contain intranuclear accumulations of amphophilic viral inclusions (arrows).)
• 02:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis4.jpg (This is a higher-power photomicrograph of epithelium at the edge of the ulcer. Amphophilic intranuclear inclusion bodies can be seen in almost all of the epithelial cells in this section.)
• 02:29, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis3.jpg (This is a medium-power photomicrograph of epithelium at the edge of the ulcer. Even at this power, amphophilic (dark, blue-purple-staining) intranuclear inclusion bodies can be seen in the epithelial cells. Note the inflammatory infiltrate in the subep...)
• 02:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis2.jpg (This higher-power photomicrograph shows the epithelium (1), the edge of the ulcer (2), and the ulcerated epithelium (3). There is an inflammatory exudate at the base of the ulcer and some necrotic cells where the epithelium once was present.)
• 02:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab8HSVGlossitis1.jpg (This is a low-power photomicrograph showing a cross section of the tongue. There is an area along the surface of the tongue where the normal epithelium has been lost and there are areas of ulceration (arrows).)
• 02:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma15.jpg (This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology and multiple mitotic figures (arrows).)
• 02:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma14.jpg (This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology.)
• 02:16, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma13.jpg (This is a high-power photomicrograph of the tumor demonstrating the anaplastic cell morphology.)
• 02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma12.jpg (This high-power photomicrograph of the tumor demonstrates the fusiform morphology of the cells. Note the marked variability in size and staining intensity of the nuclei.)
• 02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma11.jpg (This is a high-power photomicrograph of the tumor cell morphology and the periosteum (arrow).)
• 02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma10.jpg (This high-power photomicrograph demonstrates the growth pattern and the cell morphology.)
• 02:15, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma9.jpg (This high-power photomicrograph demonstrates the cellular growth pattern. Note that the cells are fusiform and they grow in sheets.)
• 02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma8.jpg (This is a high-power photomicrograph of decalcified histologic section showing the cellularity of the tumor.)
• 02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma7.jpg (This is a higher-power photomicrograph of decalcified histologic section from this tumor. There are areas of osteoid (1) and cellular areas (2).)
• 02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma6.jpg (This is a low-power photomicrograph of decalcified histologic section from this tumor. Note the blue color (cell nuclei stain blue) of much of this section indicating the increased cellularity of the tumor.)
• 02:14, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma5.jpg (These are cut sections of the distal femur containing the tumor. The periosteal involvement is evident from this picture (arrows).)
• 02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma4.jpg (This is a gross photograph of the surgical specimen with tissue dissected away to demonstrate the tumor mass.)
• 02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma3.jpg (This is another view of the tumor in the distal femur.)
• 02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma2.jpg (This is a radiograph showing the tumor in the distal femur.)
• 02:13, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Osteosarcoma1.jpg (This is a photograph of the patient prior to surgery. Note the marked swelling of the knee.)
• 02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid11.jpg (This is a high-power view of the same section stained with a silver stain to delineate carcinoid tumor cells (brown).)
• 02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid10.jpg (This is a higher-power view of the previous section stained with a silver stain to delineate carcinoid tumor cells (brown) and a mucin stain (blue) to stain the glands.)
• 02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid9.jpg (This is a low-power photomicrograph of a section of cecum containing tumor stained to demonstrate the secretory granules in these tumor cells (brown-colored stain). The blue color is the mucin in the glands just under the mucosal surface.)
• 02:08, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid8.jpg (This is a higher-power photomicrograph of the previous section showing intact mucosa (1), a gland (2), and the submucosal carcinoid tumor cells (3).)
• 02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid7.jpg (This is a low-power photomicrograph of another one of the subcutaneous masses in the cecum. The mucosa is normal and the tumor cells are in the submucosa.)
• 02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid6.jpg (This is a higher-power photomicrograph of the previous section showing the intact mucosa (right) and the submucosal carcinoid tumor.)
• 02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid5.jpg (This is a low-power photomicrograph of one of the subcutaneous masses in the cecum. Note that the mucosa (1) is virtually normal and the tumor cells are in the submucosa (2).)
• 02:07, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid4.jpg (This is a high-power photomicrograph of the surgical specimen showing the cellular morphology. The tumor cells are monotonously similar with scant, pink, granular cytoplasm and a round-to-oval stippled nucleus. As in most carcinoid tumors, there is min...)
• 02:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid3.jpg (This is a high-power photomicrograph of the surgical specimen showing the tumor's growth pattern--cells form discrete islands, trabeculae, and glands.)
• 02:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid2.jpg (This is a higher-power photomicrograph of the surgical specimen showing nests of tumor cells (arrows).)
• 02:06, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Carcinoid1.jpg (This is a low-power photomicrograph of the surgical specimen showing basophilic and eosinophilic areas delimiting areas of tumor infiltration.)
• 02:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic9.jpg (This high-power photomicrograph of tumor shows the cytologic detail of a less-differentiated area of neoplasm with cellular anaplasia.)
• 02:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic8.jpg (This is a high power photomicrograph of tumor with an area of central necrosis (arrow).)
• 02:01, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic7.jpg (This is a high-power photomicrograph showing cytologic detail of the tumor with an area of necrosis (1) and a more differentiated area with keratin pearl formation (2).)
• 02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic6.jpg (This is a photomicrograph of tumor from an area of invasion with compression of fibrous stroma and focal necrosis.)
• 02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic5.jpg (This is a higher-power photomicrograph of the mucosal surface (right) with an area of hemorrhage (arrow) and underlying tumor (left).)
• 02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic4.jpg (This is a higher-power photomicrograph of bronchus with the ulcerated mucosal surface on the right and tumor underneath.)
• 02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic3.jpg (This is a photomicrograph of bronchus with ulcerated mucosal surface on the right (1). The submucosa is completely filled with tumor down to the cartilage (2).)
• 02:00, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic2.jpg (This is a low-power photomicrograph of bronchus showing normal mucosa (1) with transition to carcinoma (2). Note the bronchial cartilage (3) and the invasion of tumor through the entire wall of the bronchus with tumor extending to the serosal surface (4).)
• 01:59, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Bronchogenic1.jpg (This is a gross photograph of bronchogenic carcinoma. The large tumor mass can be seen adjacent to the bronchus (1). Note that the epithelial surface of the bronchus is rough and irregular (2). The first branch off the right main stem bronchus is parti...)
• 01:57, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma8.jpg (This is a high-power photomicrograph of the main tumor mass showing the cellular details. The individual melanoma cells contain large nuclei with irregular contours having chromatin clumped at the periphery of the nuclear membrane and prominent red (eo...)
• 01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma7.jpg (This is a high-power photomicrograph of the main tumor mass with the cells growing as poorly formed nests and sheets of cells. There is little if any pigment in this section.)
• 01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma6.jpg (This is a higher magnification showing the abundant extracellular melanin surrounding the tumor cells (brown pigment).)
• 01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma5.jpg (This is a higher-magnification showing the abundant extracellular melanin (arrows) surrounding the tumor cells. This section of neoplasm shows the numerous cells with abundant cytoplasm and brown pigment within the cytoplasm of some of these cells.)
• 01:56, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma4.jpg (This higher-power photomicrograph shows the remaining portion of lymph node (arrow). The rest of the lymph node is invaded by a neoplasm composed of cells with lighter eosinophilic cytoplasm and pigment.)
• 01:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma3.jpg (This is a low-power photomicrograph of lymph node that is almost completely replaced/filled with tumor. This lymph node has a capsule (1) and some remaining lymphocytes (2) but the remainder of the node is replaced by tumor cells.)
• 01:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma2.jpg (This is a gross photograph of lymph nodes almost entirely replaced by black pigment (melanin).)
• 01:55, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Melanoma1.jpg (This is a gross photograph of skin with melanoma. Note the black pigment, multiple satellite nodules, and focal ulceration. Some of the satellite nodules affect the nipple.)
• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC8.jpg (This is a high-power photomicrograph demonstrating the growth pattern of the tumor. The tumor consists of malignant duct-lining cells growing in cords, solid cell nests, tubules, and glands. The cytologic detail of tumor cells varies from small cells w...)
• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC7.jpg (This is a section taken at the periphery of the tumor showing bands of tumor cells infiltrating into the fat tissue.)
• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC6.jpg (This is a section of breast tumor with abundant fibrous tissue throughout the tumor (desmoplasia, scirrhous carcinoma).)
• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC5.jpg (This is a high-power photomicrograph showing the cellular and nuclear features of the tumor cells. The large epithelial cells form glands and are medium-sized with a moderate amount of cytoplasm, vesicular nuclei, and nucleoli.)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC4.jpg (This is a higher-magnification showing abundant groups of tumor cells dissecting through the breast parenchyma - tumor infiltration (infiltrating duct cell carcinoma).)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC3.jpg (This is a section of breast with small groups of carcinoma cells throughout the breast tissue and invading through the dermis.)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC2.jpg (These are sections of normal breast (lower) and breast tissue with infiltrating duct carcinoma (upper). Note the increased cellularity (increased blue staining due to the increased number of nuclei) in the tumor tissue.)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC1.jpg (This is a gross photograph of the surgical specimen of breast with infiltrating duct carcinoma. Note the tumor tissue under the area of the nipple. The tumor infiltrates in an irregular fashion into the breast parenchyma. Note the nipple retraction cau...)
• 01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic9.jpg (This is a high-power photomicrograph of the edge of the tumor nodule in the lung. The tumor cells area growing in a glandular pattern. The area of necrosis is evident at the right side of the image.)
• 01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic8.jpg (This is a high-power photomicrograph of the edge of the tumor nodule in the lung. The tumor cells are infiltrating into the lung parenchyma (1). Even at this power you can see the glandular formation of this adenocarcinoma. There is a large area of nec...)
• 01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic7.jpg (This is a photomicrograph of a tumor nodule in the lung. The tumor cells are infiltrating into the lung parenchyma (1). There is a large area of necrosis in the center of the tumor (2).)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic6.jpg (This is a high-power photomicrograph of tumor cells that are forming glands (arrows).)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic5.jpg (This is a higher-power photomicrograph showing how the tumor cells (arrows) have infiltrated into the liver parenchyma.)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic4.jpg (This is a photomicrograph taken at the interface between the tumor (top) and the normal liver parenchyma (bottom).)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic3.jpg (These are low-power photomicrographs of a section of liver (left) and lung (right) containing tumor nodules (arrows).)
• 01:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic2.jpg (This gross photograph of the lung from this case also demonstrates multiple, variably sized pale/white-tan nodules scattered throughout the lung.)
• 01:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic1.jpg (This gross photograph of the liver from this case demonstrates multiple, variably-sized pale/white-tan nodules scattered throughout the liver.)
• 01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA9.jpg (This is a segment of distal colon from another case. Note the annular tumor that severely compromises the lumen of the colon. There is dilation of the colon proximal to the tumor.)
• 01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA8.jpg (This gross photograph from another case demonstrates an ulcerated adenocarcinoma (arrows) at the rectosigmoid junction.)
• 01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA7.jpg (This is a high-power photomicrograph of tumor cells forming glands.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA6.jpg (This is a high-power photomicrograph of tumor cells forming glands.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA5.jpg (This is a high-power photomicrograph of tumor cells invading the underlying muscularis.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA4.jpg (This is a higher-power photomicrograph of the area of transition between the normal (1) and the neoplastic (2) epithelium.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA3.jpg (This photomicrograph of the surgical specimen shows the transition between normal mucosa on the left and carcinoma which is invading the wall of the bowel (arrow).)
• 01:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA2.jpg (This is a closer view of the previous image demonstrating the raised, annular carcinoma (arrows).)
• 01:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA1.jpg (This is a gross photograph of the adenoma from the surgical specimen in this case. Note the large, ulcerated, fungating annular (encircling) carcinoma (1) with areas of hemorrhage (2). Also note the adenomatous polyps (3).)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC7.jpg (This is a high-power photomicrograph of the tumor cells that have invaded the adjacent muscle tissue.)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC6.jpg (This is a higher-power photomicrograph of bands of tumor cells (arrows) extending between the muscle bundles.)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC5.jpg (This is a photomicrograph of bands of tumor cells invading into the adjacent tissues (arrows).)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC4.jpg (This is a higher-power photomicrograph showing invasive squamous cell carcinoma. Tongues and islands of tumor cells exhibit areas of central necrosis (arrow).)
• 01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC3.jpg (This is a high-power photomicrograph demonstrating the normal epithelium undergoing transition to carcinoma (arrows).)
• 01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC2.jpg (This low-power photomicrograph of a cross-section through the esophagus at the area of constriction shows extensive infiltration of the esophageal wall with squamous cell carcinoma (arrows).)
• 01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC1.jpg (This is a gross photograph of the luminal surface of the esophagus with the area of constriction (1). The area protrudes into the lumen. There is also a central area of ulceration (2).)
• 01:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC8.jpg (This is a section of muscle tissue from this biopsy of the lip. Note that the squamous cell carcinoma has infiltrated into the muscle tissue. There are also inflammatory cells within this area of tumor infiltration.)
• 01:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC7.jpg (This is a high power photomicrograph of a poorly-differentiated area of tumor. Note the spindle-shaped cells and the irregular pattern of growth.)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC6.jpg (This is a high power photomicrograph of the well-differentiated squamous cell carcinoma. Note the intracytoplasmic keratinization which gives the cells a glassy appearance. The focal accumulations of keratinized cells are called keratin pearls (arrows).)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC5.jpg (This is a higher-power photomicrograph of infiltrating squamous cell carcinoma and inflammatory cells.)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC4.jpg (This is a higher-power photomicrograph of the well-differentiated squamous cell carcinoma and the inflammatory cell infiltration.)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC3.jpg (This photomicrograph shows a large area of ulceration (arrow) with underlying congestion and hemorrhage. The area of ulceration is adjacent to an area of tumor infiltration.)
• 01:31, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC2.jpg (This is a low-power photomicrograph of squamous cell carcinoma of the lip. Note focal ulceration (1) and tumor infiltration at the vermilion border (2).)
• 01:31, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC1.jpg (This is a pre-op photograph of this patient with an ulcerated lesion on his lip (arrow). Also note that the lip is somewhat thickened. The area for surgical excision is delineated by black marker.)
• 01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma7.jpg (This is a higher magnification of fibroadenoma showing irregularly shaped ducts lined by two layers of cells as previously described.)
• 01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma6.jpg (This is a high magnification of the fibroadenoma showing the dense stroma of the tumor surrounding the irregularly shaped duct. The ducts are lined by two cell layers, one of cuboidal, two columnar cells (inner layer) and an outer layer of flattened ce...)
• 01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma5.jpg (This is a higher-power photomicrograph of fibroadenoma showing ducts embedded in connective tissue.)
• 01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma4.jpg (This photomicrograph shows the compressed connective tissue (arrow) between two nodules of dense fibrous tissue and ducts.)
• 01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma3.jpg (This is a higher magnification of the fibroadenoma showing the dense stroma of the tumor surrounding the irregularly shaped ducts. The adjacent fibrofatty tissue containing breast ducts and lobules has been compressed by the tumor.)
• 01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma2.jpg (This is a higher magnification of one of the three nodules. At this power, the nodule seems to be composed of a solid parenchyma with small glandular spaces. The adjacent breast parenchyma consists mostly of fat.)
• 01:26, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma1.jpg (This low-power photomicrograph of the surgical specimen demonstrates three ovoid, well-circumscribed nodules surrounded by fibroadipose tissue.)
• 01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma6.jpg (This high-power photomicrograph demonstrates the relatively normal cellular morphology of this follicular adenoma.)
• 01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma5.jpg (This is a photomicrograph of an adenoma. Note that the follicular architecture is well developed and more or less uniform throughout this section.)
• 01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma4.jpg (This photomicrograph demonstrates the densely packed follicular pattern in the adenoma (left) and the larger colloid-filled follicles of the normal thyroid (right). An area of compressed thyroid is present adjacent to the adenoma (arrows).)
• 01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma3.jpg (This is another higher-power photomicrograph of the adenoma (left) and the adjacent thyroid tissue (right). Note the compression of the adjacent normal thyroid and the difference in morphology between the adenoma and the thyroid.)
• 01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma2.jpg (This is a higher-power view of the border between the tumor mass and the adjacent thyroid tissue. Note that the mass has compressed the adjacent normal thyroid tissue (arrow). Also note the different morphology between the adenoma (very cellular, dense...)
• 01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma1.jpg (This is a low-power photomicrograph of a nodule found in the thyroid of this case. Note that the mass is well-circumscribed and there is a sharp line of demarcation between the mass and the adjacent thyroid tissue (arrows).)
• 21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection10.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and cells within the renal tubules.)
• 21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection9.jpg (This is a high-power photomicrograph of cells infiltrating the wall of the blood vessel.)
• 21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection8.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium (1) and in the wall of the blood vessel (2).)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection7.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and in the wall of the blood vessel on the left.)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection6.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrate within the interstitium. There is some degeneration (coagulative necrosis) of tubules and glomeruli.)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection5.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrate within the interstitium and around the small blood vessel in the center of the image.)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection4.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrates within this kidney section. Note that in addition to the diffuse cellularity, the focal accumulations of cells appear to be focused around blood vessels.)
• 21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection3.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrates within this kidney section.)
• 21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection2.jpg (This is a low-power photomicrograph of the kidney that was removed from this patient. Even at this low power you can appreciate the focal accumulations of cells within this section and the diffuse cellular infiltrate (blue dots) throughout the kidney p...)
• 21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection1.jpg (This is a gross photograph of a kidney with acute rejection from an autopsy case. Note that the kidney is swollen (edema and inflammation) and there are areas of hemorrhage throughout the kidney.)
• 21:51, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection12.jpg (Photomicrograph from another region of previous image. Note the cellular infiltrate around a small blood vessel (right) and neutrophils within renal tubules (arrow).)
• 21:51, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection11.jpg (This is a higher-power photomicrograph of kidney from the previous image demonstrating the cellular infiltrate which is comprised of lymphocytes, macrophages, plasma cells and a few neutrophils.)
• 21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection10.jpg (This is a high-power photomicrograph of a kidney from another case of chronic transplant rejection. In this case there is extensive damage to the kidney due to the chronic rejection (loss of tubules and glomerular lesions). In addition, this kidney was...)
• 21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection9.jpg (This is a high-power photomicrograph of a damaged glomerulus. Note the loss of normal capillary structure, the mesangial expansion and the infiltration of large mononuclear cells.)
• 21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection8.jpg (This is a high-power photomicrograph of renal cortex with cellular infiltrate and few remaining renal tubules. The cellular infiltrate comprises macrophages, activated (large) lymphocytes and a few neutrophils and plasma cells.)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection7.jpg (This is a photomicrograph of a glomerulus with a mild cellular infiltrate (left) and a small damaged glomerulus (right). There is extensive interstitial fibrosis (1), loss of renal tubules, and the remaining tubules contain protein (2) indicating sever...)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection6.jpg (This is a photomicrograph of rejected kidney with a focus of cellular infiltrate (left) and a small artery with neointimal proliferation and stenosis (arrow).)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection5.jpg (This high-power photomicrograph of glomeruli from this kidney demonstrates congestion (1), increased cellularity of glomeruli with mesangial expansion, and a glomerulus that is almost completely obliterated or sclerosed (2).)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection4.jpg (This is another area of renal cortex similar to the previous image. Note the fibrosis (1) and loss of renal tubules throughout this section. Also note the focus of inflammatory cells (2) indicating that despite the chromic nature of this lesion, there ...)
• 21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection3.jpg (This is a photomicrograph of kidney with a focal area of hemorrhage around a small blood vessel (left) and congestion of the glomeruli. Note that there is a marked loss of renal tubules throughout this section with replacement by fibrous connective tis...)
• 21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection2.jpg (This is a higher-power photomicrograph of kidney containing a section of blood vessel that demonstrates a marked neointimal proliferative response (1). In this case the lumen of the artery is obliterated. Also note the cellular infiltrate in the inters...)
• 21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection1.jpg (This is a low-power photomicrograph of the kidney from this case of chronic transplant rejection. Note the focal areas of hemorrhage and inflammatory cell infiltrate in this section.)
• 21:43, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM4.jpg (This is a photograph of the vertebral column from this patient at autopsy. Notice the collapsed vertebra (1). There are multiple variably-sized white nodules (2) within the bone marrow. These are accumulations of malignant plasma cells in this case of ...)
• 21:43, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM3.jpg (This high-power photomicrograph demonstrates the cells that make up this tissue. These cells resemble plasma cells and are the malignant cell of multiple myeloma.)
• 21:42, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM2.jpg (This higher-power photomicrograph shows the junction between an amorphous hyaline-appearing area (amyloid) on the right and cellular areas (plasmacytoid cells) on the left.)
• 21:42, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM1.jpg (This is a low-power photomicrograph of the mediastinal mass. The mass is encapsulated and contains cellular areas (blue) and areas of pale red material.)
• 21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid11.jpg (This photomicrograph of the tongue demonstrates extensive amyloid deposits (1) separating the skeletal muscle fibers of the tongue. In many cases the amyloid encircles the muscle fibers (2) and these muscle fibers are atrophied.)
• 21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid10.jpg (This photomicrograph of kidney demonstrates the amyloid deposits (arrows) within glomeruli.)
• 21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid9.jpg (This is a gross photograph of kidney from this case. Note the pale yellow material within the cortex (arrows). This is indicative of amyloid within the cortex and the glomeruli. Also note that there are multiple red spots in the cortex. These represent...)
• 21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid8.jpg (This is a photomicrograph of Congo-red-stained liver tissue viewed with partially polarized light. Although not well demonstrated in this image, Congo-red-stained amyloid viewed through polarized light should give off a classic “apple green” birefr...)
• 21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid7.jpg (This is a high-power view of liver tissue stained with Congo red. The orange amyloid material (arrows) is seen clearly between liver parenchymal cells.)
• 21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid6.jpg (This is a low-power photomicrograph of liver tissue stained with Congo red (orange color in slide). Congo red reacts with amyloid and gives it an orange color (arrows).)
• 21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid5.jpg (This is a higher-power photomicrograph showing the amyloid deposits (1) between hepatocytes (2).)
• 21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid4.jpg (This is a low-power photomicrograph of liver tissue from this case. Note the eosinophilic hyaline material (1) present within and between the hepatic tissue (2). There is marked distortion of lobular architecture by the amyloid.)
• 21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid3.jpg (This is a closer view of the cut surface of this liver. The pale waxy material can be seen within the hepatic tissue (arrows).)
• 21:33, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid2.jpg (This is a gross picture of the cut surface of the liver from this case. The liver tissue is firm and has a waxy appearance--although this is difficult to appreciate in an image.)
• 21:33, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid1.jpg (This is a gross picture of liver from this case. Note the pale, swollen appearance of this liver.)
• 20:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN1.jpg (This is a low-power photomicrograph of a saggital section of end stage chronic glomerulonephritis (GN). Note the marked thinning of the cortex (arrow).)
• 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN10.jpg (For comparison this is an immunofluorescent photomicrograph of a glomerulus from a patient with Goodpasture's syndrome. The linear (arrows) immunofluorescence is characteristic of Goodpasture's syndrome.)
• 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN9.jpg (This electron micrograph demonstrates scattered subepithelial dense deposits (arrows) and a polymorphonuclear leukocyte in the lumen.)
• 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN8.jpg (This immunofluorescent photomicrograph of a glomerulus from a case of acute poststreptococcal glomerulonephritis shows a granular immunofluorescence pattern consistent with immune complex disease. The primary antibody used for this staining was specifi...)
• 20:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN7.jpg (This is a photomicrograph of a glomerulus from another case with acute poststreptococcal glomerulonephritis. In this case the immune complex glomerular disease is ongoing with necrosis and accumulation of neutrophils in the glomerulus.)
• 20:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN6.jpg (This is an electron micrograph of subepithelial granular electron dense deposits (arrows) which correspond to the granular immunofluorescence seen in the previous image.)
• 20:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN5.jpg (This is an immunofluorescent photomicrograph of granular membranous immunofluorescence (immune complex disease). The antibody used for these studies was specific for IgG.)
• 20:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN4.jpg (This is a photomicrograph of interstitial and vascular lesions in end stage renal disease.)
• 20:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN3.jpg (This is a higher-power photomicrograph of hyalinized glomeruli (1) and glomeruli with thickened basement membranes (2).)
• 20:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN2.jpg (This is a higher-power photomicrograph of hyalinized glomeruli (arrows) and glomeruli with thick basement membranes.)
• 20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis5.jpg (This is a special stain for amyloid (Luxol PAS) demonstrating the amyloid (1) and fibrosis (2) in the myocardium. The amyloid is darker purple/magenta and tends to be more amorphous. The fibrosis is pink and more fibrillar.)
• 20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis4.jpg (This is a higher-power photomicrograph of extracellular amyloid (1) and deposition of amyloid in the vessel wall (2).)
• 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis3.jpg (This is a higher-power photomicrograph of the heart tissue from this case. Note the amyloid deposition throughout the myocardium (1) as well as deposition in the wall of the blood vessel (2).)
• 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis2.jpg (This is a low power photomicrograph of the heart tissue from this case. At this magnification the structure looks relatively normal.)
• 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis1.jpg (This is a gross photograph of section of heart tissue from this case. The tissue was firm and had a waxy texture. If you use your imagination you can see pale yellow areas within this tissue which represent the amyloid deposits.)
• 20:14, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB6.jpg (This is a high-power (oil immersion) photomicrograph of granuloma stained with an acid-fast stain. Mycobacterium tuberculosis bacilli stain red.)
• 20:13, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB5.jpg (High-power photomicrograph of a TB granuloma with multinucleated giant cells adjacent to an area of caseous necrosis (to the left).)
• 20:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB4.jpg (This is a higher-power photomicrograph of a TB granuloma. The area of caseous necrosis is on the left side of the image, there are multinucleated giant cells and epithelioid macrophages throughout the remainder of the tissue.)
• 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB3.jpg (This is a higher-power photomicrograph of a TB granuloma. Note the eosinophilic material in the center of this granuloma (caseous necrosis) and the epithelioid macrophages and giant cells around the periphery.)
• 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB2.jpg (This is a low-power photomicrograph of lung tissue with multiple circumscribed nodules - granulomas (arrows).)
• 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB1.jpg (This is a photograph of a section of lung with an apical lesion. This lesion represents an old healed lesion from Mycobacterium tuberculosis infection.)
• 19:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma5.jpg (This is a gross photograph of the heart from this case. There is thickening of the left ventricular wall and some thickening of the right ventricle as well.)
• 19:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma4.jpg (This is a closer view of the cut section of lung from this patient showing the extensive fibrosis and the severe emphysematous change.)
• 19:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma3.jpg (This is a closer view of the cut section of lung from this patient. Note the extensive fibrosis and the severe emphysematous changes.)
• 19:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma2.jpg (This is a gross photograph of a cut section of one lung from this patient. Note the extensive fibrosis lower lobe (arrows).)
• 19:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma1.jpg (This is a gross photograph of cut section of the lungs from this patient. Note the extensive fibrosis of the lung parenchyma.)
• 18:00, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN13.jpg (This is a high-power photomicrograph of the affected vessel in the heart. The vessel lumen is completely occluded.)
• 18:00, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN12.jpg (This is a higher-power photomicrograph of the affected vessels in the heart (arrows). There are areas of fibrosis (old infarcts) in the myocardium adjacent to these affected vessels.)
• 17:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN11.jpg (This is a low-power photomicrograph of the heart. There are areas of fibrosis in the myocardium (arrows). Note that the large epicardial coronary artery is normal.)
• 17:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN10.jpg (This is a higher-power photomicrograph of the affected vessel from the previous image. The vessel wall is infiltrated with inflammatory cells and the vessel lumen is completely occluded (arrow).)
• 17:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN9.jpg (This is a low-power photomicrograph of the adrenal gland. There is an area of necrosis in the adrenal (1) and an affected vessel adjacent to the adrenal (2).)
• 17:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN8.jpg (This is a high-power photomicrograph of a small vessel with a rim of fibrinoid necrosis (arrow).)
• 17:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN7.jpg (This is a high-power photomicrograph of the vessel wall. There is hemorrhage and infiltration with inflammatory cells--primarily neutrophils (arrows).)
• 17:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN6.jpg (his is another example of a mesenteric artery from this case. There is a marked inflammatory cell response surrounding this vessel, fresh hemorrhage (1), and thrombotic material (2).)
• 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN5.jpg (This is a higher-power photomicrograph of this mesenteric vessel. Note the thrombotic material occluding the vessel (arrows) and the inflammatory cell infiltrate in the wall of the vessel and in the surrounding adventitia.)
• 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN4.jpg (This is a low-power photomicrograph of a mesenteric vessel from this case of polyarteritis nodosa (arrow). The vessel is completely occluded by thrombotic material and the vessel wall is infiltrated with inflammatory cells.)
• 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN3.jpg (This angiogram of the kidneys demonstrates numerous aneurysmal dilatations in the renal circulation (arrows).)
• 17:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN2.jpg (This angiogram of the liver also demonstrates numerous aneurysms throughout the hepatic circulation (arrows).)
• 17:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN1.jpg (This angiogram of the abdominal viscera demonstrates numerous aneurysms throughout the mesenteric circulation (arrows).)
• 17:47, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto9.jpg (This high-power photomicrograph shows more clearly the lymphocytes and plasma cells surrounding the thyroid gland epithelium. Large, eosinophilic, degenerating thyroid gland cells (Hurthle cells) can be seen in this section (arrows).)
• 17:47, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto8.jpg (This is a high-power photomicrograph showing the lymphocytes and plasma cells surrounding the thyroid gland epithelium.)
• 17:46, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto7.jpg (This is a high-power photomicrograph showing the inflammatory cells infiltrating into the residual thyroid tissue (arrows).)
• 17:46, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto6.jpg (This is another higher-power photomicrograph of thyroid from this case showing the inflammatory cells and the residual thyroid tissue.)
• 17:44, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto5.jpg (This is a higher-power photomicrograph of thyroid from this case showing the inflammatory cells and the residual thyroid tissue.)
• 17:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto4.jpg (This is another view of thyroid gland filled with inflammatory cells forming germinal centers (arrows).)
• 17:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto3.jpg (This is a higher-power photomicrograph of thyroid from this case. Note the large number of blue-staining inflammatory cells in this tissue. These cells appear to be forming germinal centers. Some residual thyroid gland tissue can be seen in this sectio...)
• 17:42, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto2.jpg (This is a low-power photomicrograph of thyroid from this case. Note that the tissue is more cellular than one would expect and there does not appear to be normal colloid-filled blue spaces in this gland.)
• 17:42, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto1.jpg (This is a gross photograph of thyroid gland taken at autopsy. The gland is only slightly enlarged and has a firm texture.)
• 15:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM7.jpg (This is a photomicrograph of kidney with a focal exudative lesion in a glomerulus (arrow) and sclerosis, interstitial fibrosis, and congestion.)
• 15:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM6.jpg (This is a higher-power photomicrograph of a glomerulus with nodular glomerulosclerosis (arrows). These are the classic Kimmelstiel-Wilson lesions ("K-W lesions") seen in diabetics with nodular glomerulosclerosis.)
• 15:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM5.jpg (This is a photomicrograph of a glomerulus with nodular glomerulosclerosis (1). Also note the intertubular fibrosis and the changes in the blood vessels (2).)
• 15:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM4.jpg (This is a high-power photomicrograph of two glomeruli with intercapillary glomerulosclerosis (arrows).)
• 15:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM3.jpg (This is a higher-power photomicrograph of the cortical region. In this region there is ischemic obsolescence of glomeruli and one glomerulus with nodular glomerulosclerosis (1). Also note the thickened walls of the blood vessels (2).)
• 15:26, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM2.jpg (This is a low-power photomicrograph of the kidney from this patient. The section extends from cortex (1) to the medulla (2).)
• 15:26, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM1.jpg (This is a gross photograph of the kidneys from this case. Note that there are multiple shrunken regions (old infarcts) (arrows) and the kidneys have a rough granular appearance on the surface, which is caused by multiple small infarcts of small vessels...)
• 15:20, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout8.jpg (This is a gross photograph of a tophus on the great toe of another patient with gout (arrow). The healed surgical incision and the size of this tophus indicate that this was a long-standing problem for this patient.)
• 15:20, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout7.jpg (This is a photomicrograph of a tophus that was fixed in alcohol prior to histologic processing. The alcohol fixation preserves the water soluble urate crystals within the tissue. Note the urate crystals visible in this photomicrograph (arrows). Also no...)
• 15:20, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout6.jpg (This is a high-power photomicrograph of the edge of the tophus. The character of the intense chronic inflammatory cell reaction is evident and note the presence of giant cells within this inflammatory cell reaction (arrows).)
• 15:19, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout5.jpg (This is a higher-power photomicrograph of the edge of the tophus. Most of the urate crystals dissolve away during processing. The inflammatory cells at the edge of these foci are clearly visible (arrow).)
• 15:19, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout4.jpg (This higher-power photomicrograph of the tophus demonstrates the collections of urate crystals (1) and the inflammatory cells at the edge of these foci (2).)
• 15:18, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout3.jpg (This is a low-power photomicrograph of the tophus removed from the elbow of this patient. Note the fibrous connective tissue (1) and the large foci containing the urate crystals (2) surrounded by the intense chronic inflammatory reaction.)
• 15:18, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout2.jpg (This is a gross photograph of the elbow of this patient. The subcutaneous nodules (arrows) on this arm are tophi caused by gout.)
• 15:17, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout1.jpg (This is a gross photograph of an index finger from a patient with gout. The finger has been sectioned longitudinally to demonstrate the distal interphalangeal joint. Note the white chalky material within and adjacent to the joint (arrows).)
• 15:12, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher8.jpg (This is a higher-power photomicrograph of the spleen from this case. At this higher power individual cells can be better appreciated and the fibrillar nature of the eosinophilic cytoplasmic material can be seen.)
• 15:12, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher7.jpg (This is another high-power photomicrograph of the spleen from this case. At this high power individual cells can be better appreciated.)
• 15:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher6.jpg (This is another high-power photomicrograph of the spleen from this case. At this power it is easier to see the large eosinophilic cells.)
• 15:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher5.jpg (This is a higher-power photomicrograph of the spleen from this case. Again there is no white pulp and the red pulp is filled with large eosinophilic cells.)
• 15:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher4.jpg (This is a photomicrograph of the spleen from this case. There is very little if any white pulp evident in this section.)
• 15:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher3.jpg (This is a low-power photomicrograph of normal spleen (left) and the spleen from this case (right). The loose appearance of the tissue in the Gaucher spleen is due to artifactual loss of tissue during histologic processing.)
• 15:08, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher2.jpg (This is a cut section of spleen from this case. Again note the fine granular appearance to the tissue.)
• 15:07, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher1.jpg (This is a gross photograph of spleen from this case. The spleen is enlarged and the surface is finely granular.)
• 14:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis11.jpg (This is a histologic section of pancreas from this case stained for iron (Prussian blue). Note the accumulation of iron in the parenchymal cells (1). There is also iron in the pancreatic islets (2).)
• 14:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis10.jpg (This is a histologic section of pancreas from this case. It is difficult to appreciate at this magnification, but there is brown pigment in the pancreatic acinar cells. Note the islets of Langerhans (1).)
• 14:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis9.jpg (This is a gross picture of pancreas from this case. Note the brown discoloration of the tissue.)
• 14:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis8.jpg (This higher-power view of liver stained with Prussian blue demonstrates the marked accumulation of iron within the parenchymal cells (1) and in the Kupffer cells in the periportal area (2).)
• 14:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis7.jpg (This is a low-power view of liver section stained with Prussian blue. Prussian blue reacts with iron in the tissue to give a blue color.)
• 14:54, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis6.jpg (This trichrome stain of liver section demonstrates the increased fibrous connective tissue in this liver. Note that the liver nodules (1) are surrounded by fibrous connective tissue (2).)
• 14:54, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis5.jpg (This higher-power photomicrograph demonstrates the increased fibrosis in the periportal area (1) and the pigment accumulation (2).)
• 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis4.jpg (This higher-power view of liver from this case demonstrates the nodules and the brown/black pigment within liver parenchymal cells (arrows).)
• 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis3.jpg (This is a low-power micrograph of liver from this patient. Note the nodularity of the tissue (arrows).)
• 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis2.jpg (This is a gross photograph of a cut section of liver from this case of hemochromatosis. Note that the liver is dark brown. Although hard to appreciate in a photograph, the tissue is also firm (cirrhotic).)
• 14:52, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis1.jpg (This is a gross photograph of liver (1) and pancreas (2) from this case of hemochromatosis. Note that both of these organs have a dark brown coloration.)
• 18:29, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs6.jpg (This is a karyotype of a patient with Turner syndrome (45, X).)
• 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs5.jpg (This is a karyotype of a patient with Klinefelter syndrome (47, XXY).)
• 18:28, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin12.jpg (This is a high-power photomicrograph of liver stained with periodic-acid Schiff's (PAS) stain. This demonstrates the PAS-positive granules of defective alpha 1-antitrypsin that accumulate in the Golgi of hepatocytes (arrows).)
• 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs4.jpg (FISH is also useful in the diagnosis of other genetic disorders. This is an example of FISH staining on another patient using a probe specific for DiGeorge's disease. The arrow shows that there is a deletion on chromosome 22, which is diagnostic for Di...)
• 18:28, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin11.jpg (This is a higher-power photomicrograph of a trichrome-stained section of liver. This section demonstrates the fibrosis (blue material) and the fatty change (arrows).)
• 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs3.jpg (Chromosomes from the chromosome spread are lined up to demonstrate the karyotype. In this case there are three copies of chromosome 21, just as noted in the FISH.)
• 18:27, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin10.jpg (This is a low-power photomicrograph of a trichrome-stained section of liver. There is bridging fibrosis (blue material) between portal regions.)
• 18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs2.jpg (These cells, obtained by amniocentesis, were cultured and then arrested in metaphase. Nuclei from these cells were isolated and stained to demonstrate the banding pattern of each chromosome. This photograph shows a "chromosome spread." Each chromosome ...)
• 18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs1.jpg (This is a photomicrograph of cells obtained by amniocentesis that were stained using FISH. The cell in panel 1 was stained with markers specific for the X and Y-chromosomes. The cell in panel 2 was stained with a marker specific for chromosome 18. The ...)
• 18:27, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin9.jpg (This is a low-power photomicrograph of an H&E-stained section of liver. There are increased numbers of inflammatory cells in the periportal region (arrow) and the central vein areas are pale.)
• 18:26, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin8.jpg (This is a closer view of the cut section of liver from this case. There is a definite micronodular pattern to the liver parenchyma.)
• 18:26, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin7.jpg (This is a gross photograph of the cut section of liver from this case. In this view the liver looks smaller than normal and there is a definite micronodular appearance.)
• 18:25, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin6.jpg (This is a gross photograph of the liver from this case. The capsule is somewhat thickened and the surface is slightly roughened, though it is difficult to appreciate the nodularity of the liver.)
• 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease7.jpg (Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.)
• 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease6.jpg (This is a gross photograph of a thyroid from a case of nodular goiter.)
• 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease5.jpg (This is a high-power photomicrograph of thyroid. Note the papillary projections and the moth-eaten appearance of the colloid. This appearance indicates active absorption of the colloid to form thyroglobulin.)
• 18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease4.jpg (This is a high-power photomicrograph of thyroid. Note the cellularity of the tissue with marked infolding of the epithelial tissue.)

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