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  • 18:21, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease1.jpg (This is a photograph of the thyroid from this case. Note that the gland is enlarged and is dark red.)
  • 18:09, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA10.jpg (This is a high-power photomicrograph of another region with macrophages (right), fibrocytes (left), and occasional lymphocytes throughout the lesion.)
  • 18:08, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA9.jpg (This is a high-power photomicrograph of the mononuclear cells which surround the central area of necrosis. The focal accumulations of fibrinoid material are clearly visible. Lymphocytes are present in the extreme right of this image.)
  • 18:08, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA8.jpg (This higher-power photomicrograph of the tissue illustrates the palisading nuclei of the monocytes which are located around the periphery of the central necrotic region (1).)
  • 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA7.jpg (This higher-power photomicrograph of the subcutaneous nodule again demonstrates the necrotic center and peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. There are focal accumulations of hyaline material (fibrinoid material) within...)
  • 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA6.jpg (This higher-power photomicrograph of the subcutaneous nodule shows a granulomatous lesion with a necrotic center and a peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. In the necrotic center of the granuloma there is some minerali...)
  • 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA5.jpg (This is a low-power photomicrograph of the subcutaneous nodule from this patient.)
  • 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA4.jpg (This is a gross photograph of the foot from this same patient. Note the subcutaneous nodule on the medial aspect of the foot (arrow).)
  • 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA3.jpg (This is a high-power photomicrograph of the joint capsule with another granuloma surrounding a central area of fibrinoid necrosis (arrow).)
  • 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA2.jpg (This is a medium-power photomicrograph of the joint capsule surrounding the metacarpal joints. Note the thickening of the capsule and the focal accumulation of inflammatory cells surrounding a central area of fibrinoid necrosis (arrow).)
  • 18:05, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA1.jpg (This is a gross photograph of the patient's hands at autopsy. Note the swollen joints and the deforming arthritis.)
  • 17:01, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli6.jpg (A mesenteric artery also had an atherosclerotic embolus. Again note the cholesterol clefts and thrombotic material that occlude this artery.)
  • 17:01, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli5.jpg (This is another view of this vessel with an atherosclerotic embolus. Note the cholesterol clefts (1) and thrombotic material (2) that occlude this artery.)
  • 17:01, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli4.jpg (This higher-power photomicrograph of one of the arcuate arteries reveals a cholesterol embolus. Note the needle-shaped space (arrow) within the lumen of this artery (arrow) which represents the space occupied by the cholesterol crystal that was dissolv...)
  • 17:00, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli3.jpg (This is a low-power photomicrograph of kidney tissue. Several blood vessels can be identified at the corticomedullary junction (arrows).)
  • 17:00, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli2.jpg (This is a closer view of the luminal surface of the aorta from the previous image. The rough, ulcerated surface and the thrombotic material can be easily seen in this image.)
  • 17:00, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli1.jpg (This is a gross photograph of the aorta from this patient opened lengthwise with the luminal surface visible. Note the rough surface with ulcerations and adherent thrombotic material. There is a mild dilation (aneurysm) at the distal aorta just at the ...)
  • 16:56, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli8.jpg (This is a high-powered photomicrograph of a myocardial abscess stained with a special tissue Gram stain (Brown & Brenn) to illustrate the colonies of bacteria in this myocardial tissue (arrows).)
  • 16:56, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli7.jpg (This is a higher-power photomicrograph of the abscess within the myocardium illustrating colonies of bacteria as the dark blue-staining material (arrow).)
  • 16:56, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli6.jpg (This is a low-power photomicrograph of myocardium with septic abscesses (arrows).)
  • 16:55, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli5.jpg (This is a higher-power photomicrograph of one of these septic abscesses illustrating the colonies of bacteria within necrotic cellular debris (arrows). This is typical of an abscess.)
  • 16:55, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli4.jpg (This is a higher-power photomicrograph of the focal lesions in the lung produced by the septic emboli. Note these are clearly demarcated from the relatively normal surrounding lung tissue.)
  • 16:55, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli3.jpg (This low-power photomicrograph shows a section of lung on the left and myocardium on the right. Both pieces of tissue have multiple embolic lesions seen as blue staining areas with massive infiltration of inflammatory cells (arrows).)
  • 16:54, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli2.jpg (This is a gross photograph of myocardium with multiple embolic lesions scattered throughout the left and right ventricles.)
  • 16:54, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli1.jpg (This gross photograph of lung demonstrates microabscesses due to septic embolization. Note the small 2 to 3-mm lesions scattered throughout this lung tissue (arrows).)
  • 16:50, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus10.jpg (This is a gross photograph of the fibrous band between the uterus and adjacent tissues. This fibrous scar tissue is probably left over from a previous surgery or an infection. A loop of bowel herniated through the opening produced by this fibrous band ...)
  • 16:49, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus9.jpg (This is a gross photograph of an opened abdomen at autopsy demonstrating loops of infarcted bowel (arrow). Vascular occlusion can lead to ischemic necrosis of the bowel. In this case, a section of bowel herniated through a fibrous connective tissue ban...)
  • 16:49, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus8.jpg (This is a gross photograph of cut section of testis from previous image. The tissue is filled with blood.)
  • 16:48, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus7.jpg (This is a gross photograph of an infarcted testis. Because of the anatomy of the blood supply to the testis, torsion or the blood vessels often leads to venous occlusion (due to compression of the thin walled veins) but not arterial occlusion. Thus, bl...)
  • 16:48, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus6.jpg (This is a low-power photomicrograph of the infarcted lung. The tissue is congested and has a very bland appearance due to coagulation necrosis of the lung parenchyma. You can still see the outlines of the alveoli and the cells that make-up the alveoli ...)
  • 16:48, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus5.jpg (This is a photomicrograph of the wall of the pulmonary artery (1) containing the thromboembolus. In this case the artery wall looks normal. If this was a thrombus instead of a thromboembolus, you would expect to see some damage in the artery wall that ...)
  • 16:47, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus4.jpg (This is a low-power photomicrograph of lung. A large thrombus is lodged at this branch point in the pulmonary artery. Note the hemorrhage and congestion in the surrounding lung parenchyma.)
  • 16:47, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus3.jpg (This is a gross photograph of portions of muscle from the legs including sections of leg veins. Note that the leg veins contain thrombus (arrows).)
  • 16:46, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus2.jpg (This is a gross photograph of the heart with the main pulmonary artery opened. Note the thromboembolus filling the pulmonary artery (arrows).)
  • 16:46, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thromboembolus1.jpg (This is a gross photograph of a cut section of lung demonstrating thromboemboli in the pulmonary arteries (arrows).)
  • 16:41, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis10.jpg (This is a high-power photomicrograph of the luminal surface of a re-canalized vessel. Note that the vessel lumen is lined by endothelial cells (arrows).)
  • 16:40, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis9.jpg (This is a higher-power photomicrograph of another region of the vessel wall. The adventitia (1) and the media (2) contain inflammatory cells. The recanalized portion of the vessel (3) is composed of fibrous connective tissue and contains numerous small...)
  • 16:40, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis8.jpg (This is a higher-power photomicrograph of the vessel wall. The adventitia (1) and the media (2) contain inflammatory cells. The recanalized portion of the vessel is composed of fibrous connective tissue and contains numerous small blood vessels. There ...)
  • 16:40, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis7.jpg (In this low-power photomicrograph of another coronary artery from this patient, a mural thrombus has undergone re-organization. The mural thrombus has been invaded by the in-growth of fibroblasts and small blood vessels from the wall of the artery. The...)
  • 16:39, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis6.jpg (This is a higher-power photomicrograph of thrombus attached to the wall of the vessel. Note the early organization with in-growth of fibroblasts and small blood vessels from the wall of the artery (arrows).)
  • 16:38, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis5.jpg (This is a high-power photomicrograph of thrombus attached to the wall of the vessel. There is early organization of the thrombus (arrow).)
  • 16:36, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis4.jpg (This is another high-power photomicrograph of the ruptured fibrous cap (arrows) with hemorrhage (1) into the atherosclerotic plaque. Note the presence of cholesterol crystals.)
  • 16:36, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis3.jpg (This is a higher-power photomicrograph of the ruptured fibrous cap (arrows) with hemorrhage (1) into the atherosclerotic plaque.)
  • 16:35, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis2.jpg (This is a low-power photomicrograph of thrombosed coronary artery. The thrombus (1) completely occludes the vessel. Note the layering of the thrombus. The fibrous cap is ruptured (arrow) and there is hemorrhage into the atherosclerotic plaque. Note the...)
  • 16:35, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4Thrombosis1.jpg (This is a gross photograph of thrombosed coronary artery (arrows).)
  • 16:30, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4MuralThrombus7.jpg (This high-power photomicrograph of thrombus demonstrates more clearly the components of the layers--the pale regions which contain primarily platelets (degranulated platelets) with some fibrin (1), and the red areas which contain RBCs, some leukocytes,...)
  • 16:29, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4MuralThrombus6.jpg (This is a higher-power photomicrograph of the thrombus. Note the pale regions which contain primarily platelets (degranulated platelets) with some fibrin (1), and the red areas which contain RBCs, some leukocytes, and fibrin(2).)
  • 16:29, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4MuralThrombus5.jpg (This photomicrograph illustrates the layered effect of the thrombus.)
  • 16:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4MuralThrombus4.jpg (This is a high-power photomicrograph of the border zone between the thrombus (1) and the endocardium (2). In this region there is less inflammation at the border zone.)
  • 16:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4MuralThrombus3.jpg (This higher-power photomicrograph shows the border between the thrombus on the right (1) and the endocardium on the left (2). There is a line of inflammatory cells at this interface (arrow).)
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