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• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC8.jpg (This is a high-power photomicrograph demonstrating the growth pattern of the tumor. The tumor consists of malignant duct-lining cells growing in cords, solid cell nests, tubules, and glands. The cytologic detail of tumor cells varies from small cells w...)
• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC7.jpg (This is a section taken at the periphery of the tumor showing bands of tumor cells infiltrating into the fat tissue.)
• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC6.jpg (This is a section of breast tumor with abundant fibrous tissue throughout the tumor (desmoplasia, scirrhous carcinoma).)
• 01:51, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC5.jpg (This is a high-power photomicrograph showing the cellular and nuclear features of the tumor cells. The large epithelial cells form glands and are medium-sized with a moderate amount of cytoplasm, vesicular nuclei, and nucleoli.)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC4.jpg (This is a higher-magnification showing abundant groups of tumor cells dissecting through the breast parenchyma - tumor infiltration (infiltrating duct cell carcinoma).)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC3.jpg (This is a section of breast with small groups of carcinoma cells throughout the breast tissue and invading through the dermis.)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC2.jpg (These are sections of normal breast (lower) and breast tissue with infiltrating duct carcinoma (upper). Note the increased cellularity (increased blue staining due to the increased number of nuclei) in the tumor tissue.)
• 01:50, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7IDC1.jpg (This is a gross photograph of the surgical specimen of breast with infiltrating duct carcinoma. Note the tumor tissue under the area of the nipple. The tumor infiltrates in an irregular fashion into the breast parenchyma. Note the nipple retraction cau...)
• 01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic9.jpg (This is a high-power photomicrograph of the edge of the tumor nodule in the lung. The tumor cells area growing in a glandular pattern. The area of necrosis is evident at the right side of the image.)
• 01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic8.jpg (This is a high-power photomicrograph of the edge of the tumor nodule in the lung. The tumor cells are infiltrating into the lung parenchyma (1). Even at this power you can see the glandular formation of this adenocarcinoma. There is a large area of nec...)
• 01:47, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic7.jpg (This is a photomicrograph of a tumor nodule in the lung. The tumor cells are infiltrating into the lung parenchyma (1). There is a large area of necrosis in the center of the tumor (2).)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic6.jpg (This is a high-power photomicrograph of tumor cells that are forming glands (arrows).)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic5.jpg (This is a higher-power photomicrograph showing how the tumor cells (arrows) have infiltrated into the liver parenchyma.)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic4.jpg (This is a photomicrograph taken at the interface between the tumor (top) and the normal liver parenchyma (bottom).)
• 01:46, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic3.jpg (These are low-power photomicrographs of a section of liver (left) and lung (right) containing tumor nodules (arrows).)
• 01:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic2.jpg (This gross photograph of the lung from this case also demonstrates multiple, variably sized pale/white-tan nodules scattered throughout the lung.)
• 01:45, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Metastatic1.jpg (This gross photograph of the liver from this case demonstrates multiple, variably-sized pale/white-tan nodules scattered throughout the liver.)
• 01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA9.jpg (This is a segment of distal colon from another case. Note the annular tumor that severely compromises the lumen of the colon. There is dilation of the colon proximal to the tumor.)
• 01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA8.jpg (This gross photograph from another case demonstrates an ulcerated adenocarcinoma (arrows) at the rectosigmoid junction.)
• 01:42, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA7.jpg (This is a high-power photomicrograph of tumor cells forming glands.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA6.jpg (This is a high-power photomicrograph of tumor cells forming glands.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA5.jpg (This is a high-power photomicrograph of tumor cells invading the underlying muscularis.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA4.jpg (This is a higher-power photomicrograph of the area of transition between the normal (1) and the neoplastic (2) epithelium.)
• 01:41, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA3.jpg (This photomicrograph of the surgical specimen shows the transition between normal mucosa on the left and carcinoma which is invading the wall of the bowel (arrow).)
• 01:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA2.jpg (This is a closer view of the previous image demonstrating the raised, annular carcinoma (arrows).)
• 01:40, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7ColonCA1.jpg (This is a gross photograph of the adenoma from the surgical specimen in this case. Note the large, ulcerated, fungating annular (encircling) carcinoma (1) with areas of hemorrhage (2). Also note the adenomatous polyps (3).)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC7.jpg (This is a high-power photomicrograph of the tumor cells that have invaded the adjacent muscle tissue.)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC6.jpg (This is a higher-power photomicrograph of bands of tumor cells (arrows) extending between the muscle bundles.)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC5.jpg (This is a photomicrograph of bands of tumor cells invading into the adjacent tissues (arrows).)
• 01:37, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC4.jpg (This is a higher-power photomicrograph showing invasive squamous cell carcinoma. Tongues and islands of tumor cells exhibit areas of central necrosis (arrow).)
• 01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC3.jpg (This is a high-power photomicrograph demonstrating the normal epithelium undergoing transition to carcinoma (arrows).)
• 01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC2.jpg (This low-power photomicrograph of a cross-section through the esophagus at the area of constriction shows extensive infiltration of the esophageal wall with squamous cell carcinoma (arrows).)
• 01:36, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7EsophSCC1.jpg (This is a gross photograph of the luminal surface of the esophagus with the area of constriction (1). The area protrudes into the lumen. There is also a central area of ulceration (2).)
• 01:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC8.jpg (This is a section of muscle tissue from this biopsy of the lip. Note that the squamous cell carcinoma has infiltrated into the muscle tissue. There are also inflammatory cells within this area of tumor infiltration.)
• 01:33, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC7.jpg (This is a high power photomicrograph of a poorly-differentiated area of tumor. Note the spindle-shaped cells and the irregular pattern of growth.)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC6.jpg (This is a high power photomicrograph of the well-differentiated squamous cell carcinoma. Note the intracytoplasmic keratinization which gives the cells a glassy appearance. The focal accumulations of keratinized cells are called keratin pearls (arrows).)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC5.jpg (This is a higher-power photomicrograph of infiltrating squamous cell carcinoma and inflammatory cells.)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC4.jpg (This is a higher-power photomicrograph of the well-differentiated squamous cell carcinoma and the inflammatory cell infiltration.)
• 01:32, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC3.jpg (This photomicrograph shows a large area of ulceration (arrow) with underlying congestion and hemorrhage. The area of ulceration is adjacent to an area of tumor infiltration.)
• 01:31, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC2.jpg (This is a low-power photomicrograph of squamous cell carcinoma of the lip. Note focal ulceration (1) and tumor infiltration at the vermilion border (2).)
• 01:31, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7LipSCC1.jpg (This is a pre-op photograph of this patient with an ulcerated lesion on his lip (arrow). Also note that the lip is somewhat thickened. The area for surgical excision is delineated by black marker.)
• 01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma7.jpg (This is a higher magnification of fibroadenoma showing irregularly shaped ducts lined by two layers of cells as previously described.)
• 01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma6.jpg (This is a high magnification of the fibroadenoma showing the dense stroma of the tumor surrounding the irregularly shaped duct. The ducts are lined by two cell layers, one of cuboidal, two columnar cells (inner layer) and an outer layer of flattened ce...)
• 01:28, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma5.jpg (This is a higher-power photomicrograph of fibroadenoma showing ducts embedded in connective tissue.)
• 01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma4.jpg (This photomicrograph shows the compressed connective tissue (arrow) between two nodules of dense fibrous tissue and ducts.)
• 01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma3.jpg (This is a higher magnification of the fibroadenoma showing the dense stroma of the tumor surrounding the irregularly shaped ducts. The adjacent fibrofatty tissue containing breast ducts and lobules has been compressed by the tumor.)
• 01:27, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma2.jpg (This is a higher magnification of one of the three nodules. At this power, the nodule seems to be composed of a solid parenchyma with small glandular spaces. The adjacent breast parenchyma consists mostly of fat.)
• 01:26, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Fibroadenoma1.jpg (This low-power photomicrograph of the surgical specimen demonstrates three ovoid, well-circumscribed nodules surrounded by fibroadipose tissue.)
• 01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma6.jpg (This high-power photomicrograph demonstrates the relatively normal cellular morphology of this follicular adenoma.)
• 01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma5.jpg (This is a photomicrograph of an adenoma. Note that the follicular architecture is well developed and more or less uniform throughout this section.)
• 01:23, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma4.jpg (This photomicrograph demonstrates the densely packed follicular pattern in the adenoma (left) and the larger colloid-filled follicles of the normal thyroid (right). An area of compressed thyroid is present adjacent to the adenoma (arrows).)
• 01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma3.jpg (This is another higher-power photomicrograph of the adenoma (left) and the adjacent thyroid tissue (right). Note the compression of the adjacent normal thyroid and the difference in morphology between the adenoma and the thyroid.)
• 01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma2.jpg (This is a higher-power view of the border between the tumor mass and the adjacent thyroid tissue. Note that the mass has compressed the adjacent normal thyroid tissue (arrow). Also note the different morphology between the adenoma (very cellular, dense...)
• 01:22, 21 August 2013 Seung Park (talk | contribs) uploaded File:IPLab7Adenoma1.jpg (This is a low-power photomicrograph of a nodule found in the thyroid of this case. Note that the mass is well-circumscribed and there is a sharp line of demarcation between the mass and the adjacent thyroid tissue (arrows).)
• 21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection10.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and cells within the renal tubules.)
• 21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection9.jpg (This is a high-power photomicrograph of cells infiltrating the wall of the blood vessel.)
• 21:58, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection8.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium (1) and in the wall of the blood vessel (2).)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection7.jpg (This high-power photomicrograph demonstrates the cellular infiltrate within the interstitium and in the wall of the blood vessel on the left.)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection6.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrate within the interstitium. There is some degeneration (coagulative necrosis) of tubules and glomeruli.)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection5.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrate within the interstitium and around the small blood vessel in the center of the image.)
• 21:57, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection4.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrates within this kidney section. Note that in addition to the diffuse cellularity, the focal accumulations of cells appear to be focused around blood vessels.)
• 21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection3.jpg (This is a higher-power photomicrograph demonstrating the cellular infiltrates within this kidney section.)
• 21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection2.jpg (This is a low-power photomicrograph of the kidney that was removed from this patient. Even at this low power you can appreciate the focal accumulations of cells within this section and the diffuse cellular infiltrate (blue dots) throughout the kidney p...)
• 21:56, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6AcuteRejection1.jpg (This is a gross photograph of a kidney with acute rejection from an autopsy case. Note that the kidney is swollen (edema and inflammation) and there are areas of hemorrhage throughout the kidney.)
• 21:51, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection12.jpg (Photomicrograph from another region of previous image. Note the cellular infiltrate around a small blood vessel (right) and neutrophils within renal tubules (arrow).)
• 21:51, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection11.jpg (This is a higher-power photomicrograph of kidney from the previous image demonstrating the cellular infiltrate which is comprised of lymphocytes, macrophages, plasma cells and a few neutrophils.)
• 21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection10.jpg (This is a high-power photomicrograph of a kidney from another case of chronic transplant rejection. In this case there is extensive damage to the kidney due to the chronic rejection (loss of tubules and glomerular lesions). In addition, this kidney was...)
• 21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection9.jpg (This is a high-power photomicrograph of a damaged glomerulus. Note the loss of normal capillary structure, the mesangial expansion and the infiltration of large mononuclear cells.)
• 21:50, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection8.jpg (This is a high-power photomicrograph of renal cortex with cellular infiltrate and few remaining renal tubules. The cellular infiltrate comprises macrophages, activated (large) lymphocytes and a few neutrophils and plasma cells.)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection7.jpg (This is a photomicrograph of a glomerulus with a mild cellular infiltrate (left) and a small damaged glomerulus (right). There is extensive interstitial fibrosis (1), loss of renal tubules, and the remaining tubules contain protein (2) indicating sever...)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection6.jpg (This is a photomicrograph of rejected kidney with a focus of cellular infiltrate (left) and a small artery with neointimal proliferation and stenosis (arrow).)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection5.jpg (This high-power photomicrograph of glomeruli from this kidney demonstrates congestion (1), increased cellularity of glomeruli with mesangial expansion, and a glomerulus that is almost completely obliterated or sclerosed (2).)
• 21:49, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection4.jpg (This is another area of renal cortex similar to the previous image. Note the fibrosis (1) and loss of renal tubules throughout this section. Also note the focus of inflammatory cells (2) indicating that despite the chromic nature of this lesion, there ...)
• 21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection3.jpg (This is a photomicrograph of kidney with a focal area of hemorrhage around a small blood vessel (left) and congestion of the glomeruli. Note that there is a marked loss of renal tubules throughout this section with replacement by fibrous connective tis...)
• 21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection2.jpg (This is a higher-power photomicrograph of kidney containing a section of blood vessel that demonstrates a marked neointimal proliferative response (1). In this case the lumen of the artery is obliterated. Also note the cellular infiltrate in the inters...)
• 21:48, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6ChronicRejection1.jpg (This is a low-power photomicrograph of the kidney from this case of chronic transplant rejection. Note the focal areas of hemorrhage and inflammatory cell infiltrate in this section.)
• 21:43, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM4.jpg (This is a photograph of the vertebral column from this patient at autopsy. Notice the collapsed vertebra (1). There are multiple variably-sized white nodules (2) within the bone marrow. These are accumulations of malignant plasma cells in this case of ...)
• 21:43, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM3.jpg (This high-power photomicrograph demonstrates the cells that make up this tissue. These cells resemble plasma cells and are the malignant cell of multiple myeloma.)
• 21:42, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM2.jpg (This higher-power photomicrograph shows the junction between an amorphous hyaline-appearing area (amyloid) on the right and cellular areas (plasmacytoid cells) on the left.)
• 21:42, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6MM1.jpg (This is a low-power photomicrograph of the mediastinal mass. The mass is encapsulated and contains cellular areas (blue) and areas of pale red material.)
• 21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid11.jpg (This photomicrograph of the tongue demonstrates extensive amyloid deposits (1) separating the skeletal muscle fibers of the tongue. In many cases the amyloid encircles the muscle fibers (2) and these muscle fibers are atrophied.)
• 21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid10.jpg (This photomicrograph of kidney demonstrates the amyloid deposits (arrows) within glomeruli.)
• 21:36, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid9.jpg (This is a gross photograph of kidney from this case. Note the pale yellow material within the cortex (arrows). This is indicative of amyloid within the cortex and the glomeruli. Also note that there are multiple red spots in the cortex. These represent...)
• 21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid8.jpg (This is a photomicrograph of Congo-red-stained liver tissue viewed with partially polarized light. Although not well demonstrated in this image, Congo-red-stained amyloid viewed through polarized light should give off a classic “apple green” birefr...)
• 21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid7.jpg (This is a high-power view of liver tissue stained with Congo red. The orange amyloid material (arrows) is seen clearly between liver parenchymal cells.)
• 21:35, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid6.jpg (This is a low-power photomicrograph of liver tissue stained with Congo red (orange color in slide). Congo red reacts with amyloid and gives it an orange color (arrows).)
• 21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid5.jpg (This is a higher-power photomicrograph showing the amyloid deposits (1) between hepatocytes (2).)
• 21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid4.jpg (This is a low-power photomicrograph of liver tissue from this case. Note the eosinophilic hyaline material (1) present within and between the hepatic tissue (2). There is marked distortion of lobular architecture by the amyloid.)
• 21:34, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid3.jpg (This is a closer view of the cut surface of this liver. The pale waxy material can be seen within the hepatic tissue (arrows).)
• 21:33, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid2.jpg (This is a gross picture of the cut surface of the liver from this case. The liver tissue is firm and has a waxy appearance--although this is difficult to appreciate in an image.)
• 21:33, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6Amyloid1.jpg (This is a gross picture of liver from this case. Note the pale, swollen appearance of this liver.)
• 20:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN1.jpg (This is a low-power photomicrograph of a saggital section of end stage chronic glomerulonephritis (GN). Note the marked thinning of the cortex (arrow).)
• 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN10.jpg (For comparison this is an immunofluorescent photomicrograph of a glomerulus from a patient with Goodpasture's syndrome. The linear (arrows) immunofluorescence is characteristic of Goodpasture's syndrome.)
• 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN9.jpg (This electron micrograph demonstrates scattered subepithelial dense deposits (arrows) and a polymorphonuclear leukocyte in the lumen.)
• 20:30, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN8.jpg (This immunofluorescent photomicrograph of a glomerulus from a case of acute poststreptococcal glomerulonephritis shows a granular immunofluorescence pattern consistent with immune complex disease. The primary antibody used for this staining was specifi...)
• 20:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN7.jpg (This is a photomicrograph of a glomerulus from another case with acute poststreptococcal glomerulonephritis. In this case the immune complex glomerular disease is ongoing with necrosis and accumulation of neutrophils in the glomerulus.)
• 20:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN6.jpg (This is an electron micrograph of subepithelial granular electron dense deposits (arrows) which correspond to the granular immunofluorescence seen in the previous image.)
• 20:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN5.jpg (This is an immunofluorescent photomicrograph of granular membranous immunofluorescence (immune complex disease). The antibody used for these studies was specific for IgG.)
• 20:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN4.jpg (This is a photomicrograph of interstitial and vascular lesions in end stage renal disease.)
• 20:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN3.jpg (This is a higher-power photomicrograph of hyalinized glomeruli (1) and glomeruli with thickened basement membranes (2).)
• 20:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6GN2.jpg (This is a higher-power photomicrograph of hyalinized glomeruli (arrows) and glomeruli with thick basement membranes.)
• 20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis5.jpg (This is a special stain for amyloid (Luxol PAS) demonstrating the amyloid (1) and fibrosis (2) in the myocardium. The amyloid is darker purple/magenta and tends to be more amorphous. The fibrosis is pink and more fibrillar.)
• 20:25, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis4.jpg (This is a higher-power photomicrograph of extracellular amyloid (1) and deposition of amyloid in the vessel wall (2).)
• 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis3.jpg (This is a higher-power photomicrograph of the heart tissue from this case. Note the amyloid deposition throughout the myocardium (1) as well as deposition in the wall of the blood vessel (2).)
• 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis2.jpg (This is a low power photomicrograph of the heart tissue from this case. At this magnification the structure looks relatively normal.)
• 20:24, 20 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6SenileAmyloidosis1.jpg (This is a gross photograph of section of heart tissue from this case. The tissue was firm and had a waxy texture. If you use your imagination you can see pale yellow areas within this tissue which represent the amyloid deposits.)
• 20:14, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB6.jpg (This is a high-power (oil immersion) photomicrograph of granuloma stained with an acid-fast stain. Mycobacterium tuberculosis bacilli stain red.)
• 20:13, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB5.jpg (High-power photomicrograph of a TB granuloma with multinucleated giant cells adjacent to an area of caseous necrosis (to the left).)
• 20:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB4.jpg (This is a higher-power photomicrograph of a TB granuloma. The area of caseous necrosis is on the left side of the image, there are multinucleated giant cells and epithelioid macrophages throughout the remainder of the tissue.)
• 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB3.jpg (This is a higher-power photomicrograph of a TB granuloma. Note the eosinophilic material in the center of this granuloma (caseous necrosis) and the epithelioid macrophages and giant cells around the periphery.)
• 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB2.jpg (This is a low-power photomicrograph of lung tissue with multiple circumscribed nodules - granulomas (arrows).)
• 20:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6TB1.jpg (This is a photograph of a section of lung with an apical lesion. This lesion represents an old healed lesion from Mycobacterium tuberculosis infection.)
• 19:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma5.jpg (This is a gross photograph of the heart from this case. There is thickening of the left ventricular wall and some thickening of the right ventricle as well.)
• 19:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma4.jpg (This is a closer view of the cut section of lung from this patient showing the extensive fibrosis and the severe emphysematous change.)
• 19:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma3.jpg (This is a closer view of the cut section of lung from this patient. Note the extensive fibrosis and the severe emphysematous changes.)
• 19:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma2.jpg (This is a gross photograph of a cut section of one lung from this patient. Note the extensive fibrosis lower lobe (arrows).)
• 19:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Scleroderma1.jpg (This is a gross photograph of cut section of the lungs from this patient. Note the extensive fibrosis of the lung parenchyma.)
• 18:00, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN13.jpg (This is a high-power photomicrograph of the affected vessel in the heart. The vessel lumen is completely occluded.)
• 18:00, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN12.jpg (This is a higher-power photomicrograph of the affected vessels in the heart (arrows). There are areas of fibrosis (old infarcts) in the myocardium adjacent to these affected vessels.)
• 17:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN11.jpg (This is a low-power photomicrograph of the heart. There are areas of fibrosis in the myocardium (arrows). Note that the large epicardial coronary artery is normal.)
• 17:59, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN10.jpg (This is a higher-power photomicrograph of the affected vessel from the previous image. The vessel wall is infiltrated with inflammatory cells and the vessel lumen is completely occluded (arrow).)
• 17:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN9.jpg (This is a low-power photomicrograph of the adrenal gland. There is an area of necrosis in the adrenal (1) and an affected vessel adjacent to the adrenal (2).)
• 17:58, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN8.jpg (This is a high-power photomicrograph of a small vessel with a rim of fibrinoid necrosis (arrow).)
• 17:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN7.jpg (This is a high-power photomicrograph of the vessel wall. There is hemorrhage and infiltration with inflammatory cells--primarily neutrophils (arrows).)
• 17:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN6.jpg (his is another example of a mesenteric artery from this case. There is a marked inflammatory cell response surrounding this vessel, fresh hemorrhage (1), and thrombotic material (2).)
• 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN5.jpg (This is a higher-power photomicrograph of this mesenteric vessel. Note the thrombotic material occluding the vessel (arrows) and the inflammatory cell infiltrate in the wall of the vessel and in the surrounding adventitia.)
• 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN4.jpg (This is a low-power photomicrograph of a mesenteric vessel from this case of polyarteritis nodosa (arrow). The vessel is completely occluded by thrombotic material and the vessel wall is infiltrated with inflammatory cells.)
• 17:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN3.jpg (This angiogram of the kidneys demonstrates numerous aneurysmal dilatations in the renal circulation (arrows).)
• 17:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN2.jpg (This angiogram of the liver also demonstrates numerous aneurysms throughout the hepatic circulation (arrows).)
• 17:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6PAN1.jpg (This angiogram of the abdominal viscera demonstrates numerous aneurysms throughout the mesenteric circulation (arrows).)
• 17:47, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto9.jpg (This high-power photomicrograph shows more clearly the lymphocytes and plasma cells surrounding the thyroid gland epithelium. Large, eosinophilic, degenerating thyroid gland cells (Hurthle cells) can be seen in this section (arrows).)
• 17:47, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto8.jpg (This is a high-power photomicrograph showing the lymphocytes and plasma cells surrounding the thyroid gland epithelium.)
• 17:46, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto7.jpg (This is a high-power photomicrograph showing the inflammatory cells infiltrating into the residual thyroid tissue (arrows).)
• 17:46, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto6.jpg (This is another higher-power photomicrograph of thyroid from this case showing the inflammatory cells and the residual thyroid tissue.)
• 17:44, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto5.jpg (This is a higher-power photomicrograph of thyroid from this case showing the inflammatory cells and the residual thyroid tissue.)
• 17:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto4.jpg (This is another view of thyroid gland filled with inflammatory cells forming germinal centers (arrows).)
• 17:43, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto3.jpg (This is a higher-power photomicrograph of thyroid from this case. Note the large number of blue-staining inflammatory cells in this tissue. These cells appear to be forming germinal centers. Some residual thyroid gland tissue can be seen in this sectio...)
• 17:42, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto2.jpg (This is a low-power photomicrograph of thyroid from this case. Note that the tissue is more cellular than one would expect and there does not appear to be normal colloid-filled blue spaces in this gland.)
• 17:42, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab6Hashimoto1.jpg (This is a gross photograph of thyroid gland taken at autopsy. The gland is only slightly enlarged and has a firm texture.)
• 15:29, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM7.jpg (This is a photomicrograph of kidney with a focal exudative lesion in a glomerulus (arrow) and sclerosis, interstitial fibrosis, and congestion.)
• 15:28, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM6.jpg (This is a higher-power photomicrograph of a glomerulus with nodular glomerulosclerosis (arrows). These are the classic Kimmelstiel-Wilson lesions ("K-W lesions") seen in diabetics with nodular glomerulosclerosis.)
• 15:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM5.jpg (This is a photomicrograph of a glomerulus with nodular glomerulosclerosis (1). Also note the intertubular fibrosis and the changes in the blood vessels (2).)
• 15:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM4.jpg (This is a high-power photomicrograph of two glomeruli with intercapillary glomerulosclerosis (arrows).)
• 15:27, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM3.jpg (This is a higher-power photomicrograph of the cortical region. In this region there is ischemic obsolescence of glomeruli and one glomerulus with nodular glomerulosclerosis (1). Also note the thickened walls of the blood vessels (2).)
• 15:26, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM2.jpg (This is a low-power photomicrograph of the kidney from this patient. The section extends from cortex (1) to the medulla (2).)
• 15:26, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5DM1.jpg (This is a gross photograph of the kidneys from this case. Note that there are multiple shrunken regions (old infarcts) (arrows) and the kidneys have a rough granular appearance on the surface, which is caused by multiple small infarcts of small vessels...)
• 15:20, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout8.jpg (This is a gross photograph of a tophus on the great toe of another patient with gout (arrow). The healed surgical incision and the size of this tophus indicate that this was a long-standing problem for this patient.)
• 15:20, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout7.jpg (This is a photomicrograph of a tophus that was fixed in alcohol prior to histologic processing. The alcohol fixation preserves the water soluble urate crystals within the tissue. Note the urate crystals visible in this photomicrograph (arrows). Also no...)
• 15:20, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout6.jpg (This is a high-power photomicrograph of the edge of the tophus. The character of the intense chronic inflammatory cell reaction is evident and note the presence of giant cells within this inflammatory cell reaction (arrows).)
• 15:19, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout5.jpg (This is a higher-power photomicrograph of the edge of the tophus. Most of the urate crystals dissolve away during processing. The inflammatory cells at the edge of these foci are clearly visible (arrow).)
• 15:19, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout4.jpg (This higher-power photomicrograph of the tophus demonstrates the collections of urate crystals (1) and the inflammatory cells at the edge of these foci (2).)
• 15:18, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout3.jpg (This is a low-power photomicrograph of the tophus removed from the elbow of this patient. Note the fibrous connective tissue (1) and the large foci containing the urate crystals (2) surrounded by the intense chronic inflammatory reaction.)
• 15:18, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout2.jpg (This is a gross photograph of the elbow of this patient. The subcutaneous nodules (arrows) on this arm are tophi caused by gout.)
• 15:17, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gout1.jpg (This is a gross photograph of an index finger from a patient with gout. The finger has been sectioned longitudinally to demonstrate the distal interphalangeal joint. Note the white chalky material within and adjacent to the joint (arrows).)
• 15:12, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher8.jpg (This is a higher-power photomicrograph of the spleen from this case. At this higher power individual cells can be better appreciated and the fibrillar nature of the eosinophilic cytoplasmic material can be seen.)
• 15:12, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher7.jpg (This is another high-power photomicrograph of the spleen from this case. At this high power individual cells can be better appreciated.)
• 15:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher6.jpg (This is another high-power photomicrograph of the spleen from this case. At this power it is easier to see the large eosinophilic cells.)
• 15:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher5.jpg (This is a higher-power photomicrograph of the spleen from this case. Again there is no white pulp and the red pulp is filled with large eosinophilic cells.)
• 15:11, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher4.jpg (This is a photomicrograph of the spleen from this case. There is very little if any white pulp evident in this section.)
• 15:10, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher3.jpg (This is a low-power photomicrograph of normal spleen (left) and the spleen from this case (right). The loose appearance of the tissue in the Gaucher spleen is due to artifactual loss of tissue during histologic processing.)
• 15:08, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher2.jpg (This is a cut section of spleen from this case. Again note the fine granular appearance to the tissue.)
• 15:07, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Gaucher1.jpg (This is a gross photograph of spleen from this case. The spleen is enlarged and the surface is finely granular.)
• 14:57, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis11.jpg (This is a histologic section of pancreas from this case stained for iron (Prussian blue). Note the accumulation of iron in the parenchymal cells (1). There is also iron in the pancreatic islets (2).)
• 14:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis10.jpg (This is a histologic section of pancreas from this case. It is difficult to appreciate at this magnification, but there is brown pigment in the pancreatic acinar cells. Note the islets of Langerhans (1).)
• 14:56, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis9.jpg (This is a gross picture of pancreas from this case. Note the brown discoloration of the tissue.)
• 14:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis8.jpg (This higher-power view of liver stained with Prussian blue demonstrates the marked accumulation of iron within the parenchymal cells (1) and in the Kupffer cells in the periportal area (2).)
• 14:55, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis7.jpg (This is a low-power view of liver section stained with Prussian blue. Prussian blue reacts with iron in the tissue to give a blue color.)
• 14:54, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis6.jpg (This trichrome stain of liver section demonstrates the increased fibrous connective tissue in this liver. Note that the liver nodules (1) are surrounded by fibrous connective tissue (2).)
• 14:54, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis5.jpg (This higher-power photomicrograph demonstrates the increased fibrosis in the periportal area (1) and the pigment accumulation (2).)
• 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis4.jpg (This higher-power view of liver from this case demonstrates the nodules and the brown/black pigment within liver parenchymal cells (arrows).)
• 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis3.jpg (This is a low-power micrograph of liver from this patient. Note the nodularity of the tissue (arrows).)
• 14:53, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis2.jpg (This is a gross photograph of a cut section of liver from this case of hemochromatosis. Note that the liver is dark brown. Although hard to appreciate in a photograph, the tissue is also firm (cirrhotic).)
• 14:52, 20 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Hemochromatosis1.jpg (This is a gross photograph of liver (1) and pancreas (2) from this case of hemochromatosis. Note that both of these organs have a dark brown coloration.)
• 18:29, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs6.jpg (This is a karyotype of a patient with Turner syndrome (45, X).)
• 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs5.jpg (This is a karyotype of a patient with Klinefelter syndrome (47, XXY).)
• 18:28, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin12.jpg (This is a high-power photomicrograph of liver stained with periodic-acid Schiff's (PAS) stain. This demonstrates the PAS-positive granules of defective alpha 1-antitrypsin that accumulate in the Golgi of hepatocytes (arrows).)
• 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs4.jpg (FISH is also useful in the diagnosis of other genetic disorders. This is an example of FISH staining on another patient using a probe specific for DiGeorge's disease. The arrow shows that there is a deletion on chromosome 22, which is diagnostic for Di...)
• 18:28, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin11.jpg (This is a higher-power photomicrograph of a trichrome-stained section of liver. This section demonstrates the fibrosis (blue material) and the fatty change (arrows).)
• 18:28, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs3.jpg (Chromosomes from the chromosome spread are lined up to demonstrate the karyotype. In this case there are three copies of chromosome 21, just as noted in the FISH.)
• 18:27, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin10.jpg (This is a low-power photomicrograph of a trichrome-stained section of liver. There is bridging fibrosis (blue material) between portal regions.)
• 18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs2.jpg (These cells, obtained by amniocentesis, were cultured and then arrested in metaphase. Nuclei from these cells were isolated and stained to demonstrate the banding pattern of each chromosome. This photograph shows a "chromosome spread." Each chromosome ...)
• 18:27, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab5Downs1.jpg (This is a photomicrograph of cells obtained by amniocentesis that were stained using FISH. The cell in panel 1 was stained with markers specific for the X and Y-chromosomes. The cell in panel 2 was stained with a marker specific for chromosome 18. The ...)
• 18:27, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin9.jpg (This is a low-power photomicrograph of an H&E-stained section of liver. There are increased numbers of inflammatory cells in the periportal region (arrow) and the central vein areas are pale.)
• 18:26, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin8.jpg (This is a closer view of the cut section of liver from this case. There is a definite micronodular pattern to the liver parenchyma.)
• 18:26, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin7.jpg (This is a gross photograph of the cut section of liver from this case. In this view the liver looks smaller than normal and there is a definite micronodular appearance.)
• 18:25, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin6.jpg (This is a gross photograph of the liver from this case. The capsule is somewhat thickened and the surface is slightly roughened, though it is difficult to appreciate the nodularity of the liver.)
• 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease7.jpg (Closer view of cut surface of the thyroid with nodular goiter. Note the multilobular appearance of the tissue.)
• 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease6.jpg (This is a gross photograph of a thyroid from a case of nodular goiter.)
• 18:23, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease5.jpg (This is a high-power photomicrograph of thyroid. Note the papillary projections and the moth-eaten appearance of the colloid. This appearance indicates active absorption of the colloid to form thyroglobulin.)
• 18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease4.jpg (This is a high-power photomicrograph of thyroid. Note the cellularity of the tissue with marked infolding of the epithelial tissue.)
• 18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease3.jpg (This is a higher-power photomicrograph of thyroid. The tissue is very cellular and there is little colloid.)
• 18:22, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease2.jpg (This is a low-power photomicrograph of thyroid tissue from this case. The tissue is very cellular with very little colloid.)
• 18:21, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6GravesDisease1.jpg (This is a photograph of the thyroid from this case. Note that the gland is enlarged and is dark red.)
• 18:13, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin3.jpg (This is a gross photograph of the bronchi and lungs. Note the hemorrhage in the bronchi and in the lung parenchyma.)
• 18:09, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA10.jpg (This is a high-power photomicrograph of another region with macrophages (right), fibrocytes (left), and occasional lymphocytes throughout the lesion.)
• 18:09, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin5.jpg (This is a low-power photomicrograph from an area of the lung without significant hemorrhage. The enlarged, emphysematous air spaces are easily appreciated.)
• 18:08, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA9.jpg (This is a high-power photomicrograph of the mononuclear cells which surround the central area of necrosis. The focal accumulations of fibrinoid material are clearly visible. Lymphocytes are present in the extreme right of this image.)
• 18:08, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA8.jpg (This higher-power photomicrograph of the tissue illustrates the palisading nuclei of the monocytes which are located around the periphery of the central necrotic region (1).)
• 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA7.jpg (This higher-power photomicrograph of the subcutaneous nodule again demonstrates the necrotic center and peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. There are focal accumulations of hyaline material (fibrinoid material) within...)
• 18:07, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin4.jpg (This is a gross photograph of the bronchi and lungs. Note the hemorrhage in the bronchi and in the lung parenchyma.)
• 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA6.jpg (This higher-power photomicrograph of the subcutaneous nodule shows a granulomatous lesion with a necrotic center and a peripheral rim of macrophages, fibrocytes, and occasional lymphocytes. In the necrotic center of the granuloma there is some minerali...)
• 18:07, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin2.jpg (This is a gross photograph of the cut sections of lung from this case. The lung parenchyma is markedly hemorrhagic and consolidated. Again the hemorrhage makes it difficult to appreciate the emphysematous changes.)
• 18:07, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA5.jpg (This is a low-power photomicrograph of the subcutaneous nodule from this patient.)
• 18:06, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Antitrypsin1.jpg (This is a gross photograph of the lungs from this case. The rough friable material on the surface of the lung (arrows) is fibrinous exudate and fibrous tissue. This reaction on the surface of the lung is due to the recent surgery. The emphysematous cha...)
• 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA4.jpg (This is a gross photograph of the foot from this same patient. Note the subcutaneous nodule on the medial aspect of the foot (arrow).)
• 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA3.jpg (This is a high-power photomicrograph of the joint capsule with another granuloma surrounding a central area of fibrinoid necrosis (arrow).)
• 18:06, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA2.jpg (This is a medium-power photomicrograph of the joint capsule surrounding the metacarpal joints. Note the thickening of the capsule and the focal accumulation of inflammatory cells surrounding a central area of fibrinoid necrosis (arrow).)
• 18:05, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab6RA1.jpg (This is a gross photograph of the patient's hands at autopsy. Note the swollen joints and the deforming arthritis.)
• 17:54, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney11.jpg (This is a higher-power photomicrograph of liver cyst. These cystic structures are lined by biliary epithelium.)
• 17:54, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney10.jpg (This is another photomicrograph of liver demonstrating the histologic appearance of these cysts. These cystic structures are associated with the biliary tree.)
• 17:53, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney9.jpg (This photomicrograph of liver demonstrates the histologic appearance of these cysts.)
• 17:53, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney8.jpg (This is a gross photograph of the liver from this patient. Multiple cysts can be seen on the surface of this liver (arrows).)
• 17:52, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney7.jpg (This high-power photomicrograph shows abnormal glomeruli (arrows) and some tubules.)
• 17:52, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney6.jpg (This is a higher-power photomicrograph of polycystic kidney showing the edge of a large cyst (1). In this section there are numerous tubules and dilated collecting ducts (2) that are filled with the same red proteinaceous material as the larger cysts.)
• 17:51, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney5.jpg (This is another low-power photomicrograph of an H&E-stained section from this polycystic kidney. Again note the large cystic structures (arrows)and the fibrous connective tissue throughout this section.)
• 17:51, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney4.jpg (This is a low-power photomicrograph of an H&E-stained section from this polycystic kidney. Note the large cystic structures (1), the few residual glomeruli (2), and the fibrous connective tissue throughout this section.)
• 17:49, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney3.jpg (This is a gross photograph of a cut section from one of these polycystic kidneys. Note that the renal parenchyma is almost completely replaced by cystic structures.)
• 17:44, 19 August 2013 Peter Anderson (talk | contribs) deleted page File:IPLab5PolycysticKidney3.jpg
• 17:43, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney3.jpg (This is a gross photograph of a cut section from one of these polycystic kidneys. Note that the renal parenchyma is almost completely replaced by cystic structures.)
• 17:40, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney2.jpg (This is a gross photograph of the kidneys from this case. Note that both kidneys contain multiple large cysts (arrows).)
• 17:39, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5PolycysticKidney1.jpg (This is a gross photograph of the kidneys from this case. Note that both kidneys contain multiple large cysts (arrows).)
• 17:22, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis8.jpg (This is a high-power photomicrograph of the cells in the neurofibroma.)
• 17:21, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis7.jpg (This higher-power photomicrograph of the neurofibroma shows more clearly the elongated cells (primarily Schwann cells) that make up this tumor.)
• 17:21, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis6.jpg (This is a higher-power photomicrograph of the neurofibroma demonstrating the loose pattern of elongated cells making up the tumor mass.)
• 17:20, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis5.jpg (This is a higher-power photomicrograph of the neurofibroma (1) with the overlying skin (2).)
• 17:19, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis4.jpg (This is a low-power photomicrograph of a subcutaneous neurofibroma (1). Note the increased pigmentation in the skin (2).)
• 17:19, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis3.jpg (This is a closer view of neurofibromas on the skin.)
• 17:19, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis2.jpg (This is another view taken at autopsy demonstrating the neurofibromas. Some lesions can be seen as subcutaneous swellings (arrow) and others form pedunculated masses. Most are hyperpigmented.)
• 17:18, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab5Neurofibromatosis1.jpg (This photograph, taken at autopsy, demonstrates the distribution of neurofibromas on the skin of this patient.)
• 17:02, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange12.jpg (This is a cut surface of the same tissue seen in the previous slide. Note the marked nodular pattern. The paler-staining areas between the round nodules represent fibrous connective tissue.)
• 17:01, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli6.jpg (A mesenteric artery also had an atherosclerotic embolus. Again note the cholesterol clefts and thrombotic material that occlude this artery.)
• 17:01, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli5.jpg (This is another view of this vessel with an atherosclerotic embolus. Note the cholesterol clefts (1) and thrombotic material (2) that occlude this artery.)
• 17:01, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli4.jpg (This higher-power photomicrograph of one of the arcuate arteries reveals a cholesterol embolus. Note the needle-shaped space (arrow) within the lumen of this artery (arrow) which represents the space occupied by the cholesterol crystal that was dissolv...)
• 17:00, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli3.jpg (This is a low-power photomicrograph of kidney tissue. Several blood vessels can be identified at the corticomedullary junction (arrows).)
• 17:00, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange11.jpg (This gross photograph of liver demonstrates severe nodular cirrhosis. Note the extensive scarring of the capsule and the nodular projections of tissue through the uncut capsule in this tissue. The green color is due to the accumulation of bile pigment.)
• 17:00, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli2.jpg (This is a closer view of the luminal surface of the aorta from the previous image. The rough, ulcerated surface and the thrombotic material can be easily seen in this image.)
• 17:00, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange10.jpg (This is a low-power photomicrograph of liver stained with a trichrome stain. In this section, connective tissue stains green (arrows) and hepatic parenchymal cells are red. Note that many of the parenchymal cells have clear spaces indicating fatty dege...)
• 17:00, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4AtheromatousEmboli1.jpg (This is a gross photograph of the aorta from this patient opened lengthwise with the luminal surface visible. Note the rough surface with ulcerations and adherent thrombotic material. There is a mild dilation (aneurysm) at the distal aorta just at the ...)
• 16:59, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange9.jpg (This photomicrograph of the liver is from another patient with a history of alcohol use. There are some clear vacuoles indicating fat droplets (1) and there are numerous red-staining granular deposits within the cytoplasm of hepatocytes (2)--this is al...)
• 16:58, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange8.jpg (An oil red O stain for fat was performed on a frozen section of this liver tissue. The red droplets represent fat in the tissue which is typical of fatty degeneration in the liver. By using frozen sections the tissues do not have to be dehydrated throu...)
• 16:58, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange7.jpg (A high-power photomicrograph of the liver parenchyma shows that each individual liver cell is filled with a large, clear droplet which represents the space remaining after lipid was dissolved by the dehydration procedure used to embed the tissue. '''No...)
• 16:57, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange6.jpg (Another view at the same power illustrates the proliferation of bile ducts in the interlobular and perichordal regions (arrows).)
• 16:56, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli8.jpg (This is a high-powered photomicrograph of a myocardial abscess stained with a special tissue Gram stain (Brown & Brenn) to illustrate the colonies of bacteria in this myocardial tissue (arrows).)
• 16:56, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange5.jpg (This higher-power photomicrograph of the centrilobular area gives the appearance of fatty tissue, as indicated by many empty spaces. Very few normal liver cells can be seen in this slide. A few more normal-appearing hepatocytes are present at the left ...)
• 16:56, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli7.jpg (This is a higher-power photomicrograph of the abscess within the myocardium illustrating colonies of bacteria as the dark blue-staining material (arrow).)
• 16:56, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli6.jpg (This is a low-power photomicrograph of myocardium with septic abscesses (arrows).)
• 16:56, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange4.jpg (A higher-power photomicrograph illustrates more clearly the inflammatory cells (arrows) around the portal areas.)
• 16:55, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli5.jpg (This is a higher-power photomicrograph of one of these septic abscesses illustrating the colonies of bacteria within necrotic cellular debris (arrows). This is typical of an abscess.)
• 16:55, 19 August 2013 Peter Anderson (talk | contribs) uploaded File:IPLab2FattyChange3.jpg (Another low-power photomicrograph illustrates again the pale, washed-out appearance of this tissue. Notice the numerous holes throughout the tissue. There are accumulations of inflammatory cells (arrows) around portal tracts.)
• 16:55, 19 August 2013 Seung Park (talk | contribs) uploaded File:IPLab4SepticEmboli4.jpg (This is a higher-power photomicrograph of the focal lesions in the lung produced by the septic emboli. Note these are clearly demarcated from the relatively normal surrounding lung tissue.)

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