IPLab:Lab 7:Osteosarcoma

From Pathology Education Instructional Resource
Revision as of 20:49, 9 July 2020 by Peter Anderson (talk | contribs) (Autopsy Findings)
Jump to: navigation, search

Clinical Summary[edit]

This 14-year-old male first experienced mild pain in the left knee after playing baseball, approximately two months ago. The pain persisted in an intermittent fashion until approximately two weeks prior to admission, when the pain increased significantly and was accompanied by marked swelling and loss of motion. He also had decreased appetite, lethargy, and a 10-pound weight loss. On physical examination, the left knee was enlarged diffusely, firm, and non-tender. Radiographic and biopsy results confirmed a diagnosis of osteosarcoma. The patient underwent surgical removal of the distal femur and knee with placement of a prosthetic knee joint and bone grafts.

The distal diaphysis of the femur and adjacent soft tissues were involved in a 15 x 10 x 10-cm mass. The cut surface of the mass was fleshy white, with focal areas of hemorrhage.


Virtual Microscopy[edit]

Study Question[edit]

Additional Resources[edit]


Journal Articles[edit]


The normal fibrinogen level is 184 to 412 mg/dL.