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IPLab:Lab 7:Metastatic Adenocarcinoma

939 bytes added, 01:52, 9 July 2020
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== Clinical Summary ==
This 58-year-old male was admitted five weeks earlier with a weight loss of 80 pounds over a six-month period, abdominal cramps, and rebound tenderness in the right lower quadrant. Abdominal and chest x-rays imaging showed multiple nodular radiopacities masses in the lungs and liver. Fine needle biopsy of the liver revealed adenocarcinoma with the primary source thought to be colon. He was discharged on chemotherapy, but returned two days later with small bowel obstruction and sepsis, and he died a few days later.
== Autopsy Findings == Autopsy revealed an obstructive firm mass in the cecum with similar masses in the lungs, lymph nodes, liver and peritoneum. A large retrocecal abscess was found. Blood cultures grew Klebsiella pneumoniae and E. coli.
== Images ==
<gallery heights="250px" widths="250px">
File:IPLab7Metastatic1a.jpg|Abdominal CT showing multiple nodular masses in the liver.
File:IPLab7Metastatic1.jpg|This gross photograph of the liver from this case demonstrates multiple, variably-sized pale/white-tan nodules scattered throughout the liver.
File:IPLab7Metastatic2.jpg|This gross photograph of the lung from this case also demonstrates multiple, variably sized pale/white-tan nodules scattered throughout the lung.
File:IPLab7Metastatic9.jpg|This is a high-power photomicrograph of the edge of the tumor nodule in the lung. The tumor cells area growing in a glandular pattern. The area of necrosis is evident at the right side of the image.
</gallery>
 
== Virtual Microscopy ==
=== Lung ===
<peir-vm>IPLab7Metastatic_Lung</peir-vm>
 
=== Liver ===
<peir-vm>IPLab7Metastatic_Liver</peir-vm>
== Study Questions ==
=== Images ===
* [{{SERVER}}/library/index.php?/tags/219-adenocarcinoma PEIR Digital Library: Adenocarcinoma Images]* [{{SERVER}}/library/index.php?/tags/415-metastatic_adenocarcinoma PEIR Digital Library: Metastatic Adenocarcinoma Images]* [http://library.med.utah.edu/WebPath/LIVEHTML/LIVERIDX.html#4 WebPath: Hepatic Neoplasms]* [http://library.med.utah.edu/WebPath/LUNGHTML/LUNGIDX.html#8 WebPath: Lung Neoplasms]
== Related IPLab Cases ==
* [[IPLab:Lab 7:Adenocarcinoma|Lab 7: Colon: Adenocarcinoma]]* [[IPLab:Lab 7:Lip SCC|Lab 7: Lip: Squamous Cell Carcinoma]]* [[IPLab:Lab 7:Esophagus SCC|Lab 7: Esophagus: Squamous Cell Carcinoma]]* [[IPLab:Lab 7:IDC|Lab 7: Breast: Infiltrating Ductal Carcinoma]]* [[IPLab:Lab 7:Bronchogenic Carcinoma|Lab 7: Lung: Bronchogenic Carcinoma]]
{{IPLab 7}}
[[Category: IPLab:Lab 7]]

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