IPLab:Lab 6:Objectives

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  • Review in general terms the organization and effector cells of the immune system.
  • Describe the Arthus reaction and serum sickness and relate them to hypersensitivity reactions.
  • Define and describe the clinical, pathologic, and clinical laboratory features of rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis/polymyositis, Sjögren's syndrome, polyarteritis nodosa, and mixed connective tissue disease.
  • Classify the histocompatibility antigens and how they relate to the major histocompatibility complex and to transplantation.
  • Know prototypic organ rejection processes, giving the chronologic, immunologic, and morphologic features of each.
  • Know the physical characteristics of amyloid which make it unique.
  • Understand the different disease processes that can lead to amyloidosis and be able to characterize the different clinical sequelae of amyloidosis.