Open main menu

Pathology Education Instructional Resource β

Changes

IPLab:Lab 4:Mural Thrombus

558 bytes added, 01:57, 24 June 2020
Autopsy Findings
== Clinical Summary ==
This 67-year-old female was transferred to the hospital from a nursing home in a comatose state. Physical findings on examination were compatible with brain stem infarction. On the fourth hospital day, an electrocardiogram revealed changes compatible with anterior myocardial infarction. The patient remained comatose with quadriplegia and expired on the 16th hospital day.
This 67-year-old female was transferred to the hospital from a nursing home in a comatose state. Physical findings on examination were compatible with brain stem infarction. On the fourth hospital day, an electrocardiogram revealed changes compatible with anterior myocardial infarction. The patient remained comatose with quadriplegia and expired on the 16th hospital day.  == Autopsy Findings == Examination of the brain revealed extensive infarction involving the midbrain and cerebellum with complete occlusion of the upper one-half of the basilar artery; there was also extensive coronary artery atherosclerosis. A large aneurysm of the left ventricle was present; this was filled with mural thrombus. Extensive infarction of the lateral and posterior portions of the left ventricular wall toward the base of the heart was also found.
== Images ==
File:IPLab4MuralThrombus7.jpg|This high-power photomicrograph of thrombus demonstrates more clearly the components of the layers--the pale regions which contain primarily platelets (degranulated platelets) with some fibrin (1), and the red areas which contain RBCs, some leukocytes, and fibrin (2).
</gallery>
 
== Virtual Microscopy ==
=== Heart:Mural Thrombus ===
<peir-vm>IPLab4MuralThrombus</peir-vm>
 
=== Normal Heart ===
<peir-vm>IPLab2Hypertrophy_normal_Heart</peir-vm>
== Study Questions ==
=== Images ===
* [http://peir.path.uab.edu{{SERVER}}/library/index.php?/tags/424-mural_thrombus PEIR Digital Library: Mural Thrombus Images]
* [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html#3 WebPath: Myocardial Infarction]
* [http://library.med.utah.edu/WebPath/CVHTML/CVIDX.html#2 WebPath: Atherosclerotic Cardiovascular Disease]
== Related IPLab Cases ==
* [[IPLab:Lab 1:Myocardial Infarction|Lab 1: Heart: Myocardial Infarction (Coagulative Necrosis)]]* [[IPLab:Lab 3:Acute Myocardial Infarction|Lab 3: Heart: Acute Myocardial Infarction]]* [[IPLab:Lab 3:Healed Myocardial Infarction|Lab 3: Heart: Healed Myocardial Infarction]]* [[IPLab:Lab 4:Thrombosis|Lab 4: Coronary Artery: Thrombosis]]* [[IPLab:Lab 4:Pulmonary Congestion and Edema|Lab 4: Lung: Pulmonary Congestion and Edema]]
{{IPLab 4}}
[[Category: IPLab:Lab 4]]