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IPLab:Lab 1:Tuberculosis

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Contents

Clinical SummaryEdit

This 70-year-old man was admitted to the hospital with a three week history of upper abdominal pain, anorexia, nausea, and general malaise. His hospital stay was characterized by fever and severe respiratory distress. There were multiple densities in the patient's chest x-ray consistent with pneumonia and examination of a stained sputum specimen showed acid fast bacilli. Despite appropriate therapy, the patient died 14 days after admission.

Autopsy findings demonstrated pulmonary tuberculosis with widespread dissemination throughout the body. Multiple gray-white nodules ranging from pinpoint size up to 1 cm were diffusely distributed throughout the lung parenchyma.

ImagesEdit

Virtual MicroscopyEdit

Lung: TuberculosisEdit

Normal LungEdit

Study QuestionsEdit


Additional ResourcesEdit

Related IPLab CasesEdit

In alcoholics, aspiration pneumonia is common--bacteria enter the lung via aspiration of gastric contents.

Acid fast bacilli are not easily decolorized by acid during staining. This is characteristic of mycobacteria.

Disseminated tuberculosis refers to the hematogenous spread of tuberculous lesions throughout the body. It is also known as miliary tuberculosis (which is so-called because the lesions resemble millet).

A tuberculosis granuloma is a focus of granulomatous inflammation caused by CHRONIC tuberculosis infection. The granuloma consists of epithelioid cells (activated macrophages) surrounded by lymphocytes, plasma cells, and fibroblasts.

Anthracotic pigment is coal dust deposited in the lungs--it is seen in coal miners, city-dwellers, and smokers.

Disseminated tuberculosis refers to the hematogenous spread of tuberculous lesions throughout the body. It is also known as miliary tuberculosis (which is so-called because the lesions resemble millet).

Caseous means cheesy.